| Literature DB >> 35587874 |
Hardeep Singh1,2,3,4, Terence Tang5,6, Carolyn Steele Gray7,8, Kristina Kokorelias9, Rachel Thombs7, Donna Plett5,8, Matthew Heffernan3, Carlotta M Jarach10, Alana Armas2,7, Susan Law5,8, Heather V Cunningham11, Jason Xin Nie5, Moriah E Ellen8,12, Kednapa Thavorn13,14, Michelle LA Nelson2,7,8.
Abstract
BACKGROUND: Older adults experience a high risk of adverse events during hospital-to-home transitions. Implementation barriers have prevented widespread clinical uptake of the various digital health technologies that aim to support hospital-to-home transitions.Entities:
Keywords: aged; health; medical informatics; mobile phone; transitions
Year: 2022 PMID: 35587874 PMCID: PMC9164100 DOI: 10.2196/35929
Source DB: PubMed Journal: JMIR Aging ISSN: 2561-7605
Figure 1PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flow diagram. Adapted from Moher et al [111].
Study characteristics.
| Study | Country | Medical condition and intervention details |
| Amir et al, 2017 [ | Israel | Cardiac (heart failure) |
| Ammenwerth et al, 2015 [ | Austria | Cardiac (coronary heart disease) |
| Amroze et al, 2019 [ | United States | Non–condition-specific criteria |
| Andikyan et al, 2012 [ | United States | Cancer (gynecologic cancer) |
| Arcilla et al, 2019 [ | United States | Multiple chronic conditions (eg, congestive heart failure, chronic obstructive pulmonary disease, and diabetes mellitus) |
| Austin et al, 2012 [ | United States | Cardiac (congestive heart failure) |
| Avery et al, 2019 [ | United Kingdom | Cancer (major abdominal surgery, including surgery for esophageal, gastric, or hepato-pancreato-biliary cancer) |
| Aziz et al, 2011 [ | United Kingdom | Surgery (abdominal surgery) |
| Backman et al, 2020 [ | Canada | Orthopedic (after hip fracture) |
| Barken et al, 2018 [ | Norway | Respiratory (chronic obstructive pulmonary disease) |
| Barnason et al, 2019 [ | United States | Cardiac (coronary artery bypass surgery or percutaneous coronary intervention) |
| Bednarski et al, 2019 [ | United States | Cancer (colorectal cancer surgery) |
| Belarmino et al, 2019 [ | United States | Cancer (radical prostatectomy) |
| Bernocchi et al, 2016 [ | Italy | Neurological (stroke) |
| Bernocchi et al, 2012 [ | Italy | Multiple conditions (chronic obstructive pulmonary disease, cardiac, dermatologic, diabetes, pulmonological, traumatic brain injury, and stroke) |
| Boeni et al, 2015 [ | Switzerland | Diabetes |
| Book et al, 2013 [ | Germany | Cancer (prostate, bladder, kidney, breast, or other types of cancer) |
| Bouwsma et al, 2018 [ | Netherlands | Surgery (gynecological surgery) |
| Bouwsma et al, 2018 [ | Netherlands | Surgery (gynecological surgery) |
| Campbell et al, 2019 [ | United States | Orthopedic (total knee or hip arthroplasty) |
| Carrier et al, 2016 [ | France | Cancer (colorectal surgery) |
| Chang et al, 2020 [ | China | Cancer (esophagectomy) |
| Chen et al, 2010 [ | Australia | Patients admitted to the aged care hospital ward |
| Chen et al, 2019 [ | China | Cardiac (chronic heart failure) |
| Chiang et al, 2012 [ | China | Cardiac (chronic heart failure) |
| Cox et al, 2018 [ | United States | Medical and surgical intensive care unit patients (receipt of mechanical ventilation for >48 consecutive hours and successful extubation before discharge) |
| Cox et al, 2019 [ | United States | Cardiac (cardiorespiratory failure) |
| Davis et al, 2015 [ | United States | Multiple conditions (acute chronic disease) |
| Day et al, 2018 [ | United States | Orthopedic (total joint arthroplasty) |
| Dendale et al, 2012 [ | United States | Cardiac (severe heart failure) |
| DeVito Dabbs et al, 2016 [ | United States | Surgery (lung transplantation) |
| DeVon et al, 2010 [ | United States | Cardiac (coronary heart disease) |
| Dexter et al, 2013 [ | United States | Orthopedic (total hip replacement) |
| Dorothy et al, 2016 [ | United States | Cardiac (cardiovascular surgery) |
| Duncan et al, 2018 [ | United States | Neurological (stroke and transient ischemic attack) |
| Dunn et al, 2015 [ | United States | Patients on medical or surgical units on warfarin |
| El-Kareh et al, 2012 [ | United States | Patients with positive and untreated or undertreated blood, urine, sputum, or cerebral spinal fluid cultures |
| Evangelista et al, 2015 [ | United States | Cardiac (chronic heart failure) |
| Finn et al, 2011 [ | United States | Patients on medical service |
| Fitzsimmons et al, 2016 [ | United Kingdom | Respiratory (chronic obstructive pulmonary disease) |
| Frail et al, 2016 [ | United States | Patients taking ≥1 long-term medication |
| Gesell et al, 2019 [ | United States | Neurological (stroke) |
| Gunter et al, 2018 [ | United States | Surgery (vascular surgery) |
| Gurwitz et al, 2014 [ | United States | Patients being discharged from an inpatient unit |
| Gustavell et al, 2019 [ | Sweden | Cancer (pancreaticoduodenectomy) |
| Gustavell et al, 2019 [ | Sweden | Cancer (pancreaticoduodenectomy) |
| Haynes et al, 2020 [ | United States | Cardiac (decompensated heart failure) |
| Heaton et al, 2019 [ | United States | Multiple conditions (acute myocardial infarction, pneumonia, congestive heart failure, chronic obstructive pulmonary disease, or diabetes) |
| Heiney et al, 2020 [ | United States | Cardiac (heart failure) |
| Hewner et al, 2014 [ | United States | Multiple conditions |
| Ho et al, 2016 [ | China | Respiratory (chronic obstructive pulmonary disease) |
| Holleck et al, 2017 [ | United States | Patients admitted to medical service |
| Holt et al, 2011 [ | United States | Surgery (plastic surgery) |
| Hu et al, 2014 [ | China | Cardiac (percutaneous coronary intervention) |
| Jayaram et al, 2017 [ | United States | Cardiac (heart failure) |
| Jeungok et al, 2017 [ | United States | Orthopedic |
| Jonker et al, 2020 [ | Netherlands | Cancer (elective oncologic resection of a solid tumor) |
| Kamoen et al, 2020 [ | Belgium | Neurological (ischemic stroke) |
| Kang et al, 2019 [ | China | Neurological (stroke) |
| Karapinar-Çarkit et al, 2014 [ | Netherlands | Patients discharged from the cardiology and respiratory wards |
| Katz et al, 2016 [ | United States | Cancer (pancreatectomy) |
| Keeping-Burke et al, 2013 [ | Canada | Cardiac (coronary artery bypass graft surgery) |
| Khan et al, 2018 [ | Denmark | Cardiac (on- or off-pump coronary |
| Klement et al, 2019 [ | United States | Orthopedic (total joint arthroplasty) |
| Kogut et al, 2014 [ | United States | Chronic medical conditions |
| Lacson et al, 2018 [ | United States | Respiratory (pulmonary nodules) |
| Lafaro et al, 2020 [ | United States | Cancer (colorectal, gastric, pancreatic, and liver cancer surgery) |
| Lavu et al, 2019 [ | United States | Surgery (pancreaticoduodenectomy) |
| Layton et al, 2014 [ | United States | Cardiac (coronary artery disease or congestive heart failure) |
| Lehnbom et al, 2014 [ | Australia | Patients discharged from a hospital unit |
| Lin et al, 2020 [ | China | Cardiac (coronary artery disease) |
| Lindhardt et al, 2017 [ | Denmark | Patients admitted to internal medicine units and at nutritional risk |
| Lowres et al, 2016 [ | Australia | Cardiac (cardiac surgery) |
| Luo et al, 2019 [ | China | Orthopedic (total hip arthroplasty) |
| Lyu et al, 2016 [ | China | Cancer (head and neck tumor) |
| Madigan et al, 2013 [ | United States | Cardiac (heart failure) |
| Markle-Reid et al, 2020 [ | Canada | Neurological (stroke and multimorbidity) |
| Martirosov et al, 2020 [ | United States | Patients admitted to hospital |
| Mathar et al, 2015 [ | Denmark | Respiratory (chronic obstructive pulmonary disease) |
| McCloskey et al, 2015 [ | Canada | Patients discharged from geriatric rehabilitation |
| McGillion et al, 2020 [ | Canada and United Kingdom | Cardiac and major vascular surgery |
| Melholt et al, 2018 [ | Denmark | Cardiac (ischemic heart disease or heart failure, including patients who had undergone coronary artery bypass or valve surgery) |
| Meng-Yao et al, 2020 [ | China | Neurological (stroke) |
| Metcalf et al, 2019 [ | United States | Cancer (radical cystectomy) |
| Moffet et al, 2015 [ | Canada | Orthopedic (total knee arthroplasty) |
| Moro Agud et al, 2016 [ | Spain | Patients admitted to a hospital unit |
| Mousa et al, 2019 [ | United States | Surgery (arterial revascularization with groin incision) |
| Moy et al, 2014 [ | United States | Patients admitted to medical service |
| Nazar et al, 2016 [ | United Kingdom | Patients on ≥4 medicines or had changes in medicines during the hospital stay |
| Newnham et al, 2015 [ | Australia | Patients discharged from the acute general medical ward |
| Nielsen et al, 2020 [ | Denmark | Surgery (kidney transplantation) |
| Nilsson et al, 2020 [ | Sweden | Cancer (prostate cancer surgery) |
| Nundy et al, 2013 [ | United States | Cardiac (heart failure) |
| Ong et al, 2016 [ | United States | Cardiac (heart failure) |
| Ostrovsky et al, 2016 [ | United States | Non–condition-specific criteria (medical fee-for-service patients) |
| Park et al, 2017 [ | South Korea | Orthopedic (total knee replacement) |
| Pastora-Bernal et al, 2018 [ | Spain | Orthopedic (arthroscopic subacromial decompression) |
| Pavic et al, 2020 [ | Switzerland | Cancer (palliative cancer care) |
| Pavic et al, 2020 [ | Switzerland | Cancer (palliative cancer care) |
| Pedone et al, 2015 [ | Italy | Cardiac (heart failure) |
| Piau et al, 2019 [ | United States | Cancer |
| Piette et al, 2020 [ | United States | Patients admitted with an illness that is associated with increased rehospitalization risk |
| Ponce et al, 2016 [ | United States | Surgery (neurosurgical or orthopedic) |
| Prince et al, 2019 [ | United States | Cancer (hematologic malignancies) |
| Ramkumar et al, 2019 [ | United States | Orthopedic (total knee arthroplasty) |
| Reed et al, 2020 [ | United States | Diabetes |
| Reider-Demer et al, 2018 [ | United States | Neurological (elective neurosurgery) |
| Requena et al, 2019 [ | Spain | Neurological (stroke) |
| Ritchie et al, 2016 [ | United States | Multiple conditions (heart failure and chronic obstructive pulmonary disease) |
| Sabir et al, 2019 [ | United Kingdom | Non–condition-specific criteria |
| Saleh et al, 2014 [ | Norway | Respiratory (chronic obstructive pulmonary disease) |
| Santana et al, 2017 [ | Canada | Patients admitted to medical teaching units with multiple comorbidities and complicated medication profiles |
| Scheper et al, 2019 [ | Netherlands | Orthopedic (joint arthroplasty) |
| Schneider et al, 2017 [ | United States | Neurological (stroke) |
| Sinha et al, 2019 [ | United States | Patients admitted to general medicine service |
| Smith et al, 2016 [ | United States | Patients admitted to general medicine, geriatrics, or cardiology inpatient services; medically complex (≥2 comorbid conditions) |
| Sorknaes et al, 2011 [ | Denmark | Respiratory (chronic obstructive pulmonary disease) |
| Sorknaes et al, 2013 [ | Denmark | Respiratory (chronic obstructive pulmonary disease) |
| Sui et al, 2020 [ | China | Cancer (surgical resection for non–small cell lung cancer) |
| Sun et al, 2017 [ | United States | Cancer (major abdominal cancer surgery) |
| Sun et al, 2017 [ | United States | Cancer (lung cancer surgery) |
| Tamblyn et al, 2019 [ | Canada | Patients admitted to medical and surgical hospital units |
| Tamblyn et al, 2018 [ | Canada | Patients admitted to medical and surgical hospital units |
| Timmers et al, 2019 [ | Netherlands | Orthopedic (total knee replacement) |
| Treskes et al, 2020 [ | Netherlands | Cardiac (myocardial infarction) |
| van den Berg et al, 2016 [ | Australia | Neurological (stroke) |
| Van der Meij et al, 2018 [ | Netherlands | Surgery (intermediate-grade abdominal surgery) |
| Vest et al, 2015 [ | United States | Non–condition-specific criteria |
| Vesterby et al, 2017 [ | Denmark | Orthopedic (fast-track hip replacement) |
| Vianello et al, 2016 [ | Italy | Respiratory (chronic obstructive pulmonary disease) |
| Villani et al, 2014 [ | Italy | Cardiac (heart failure) |
| Wade et al, 2012 [ | Australia | Frail older adults with multiple chronic conditions |
| Wang et al, 2017 [ | China | Respiratory (chronic obstructive pulmonary disease) |
| Wang et al, 2018 [ | China | Cancer (colorectal cancer or other digestive and |
| Wang et al, 2018 [ | China | Orthopedic (hip replacement surgery) |
| Wan et al, 2018 [ | China | Neurological (hypertensive ischemic stroke) |
| Whitehouse et al, 2020 [ | United States | Diabetes |
| Wilcock et al, 2019 [ | United Kingdom | Patients admitted to a hospital |
| Wolf et al, 2016 [ | Sweden | Cardiac (acute coronary syndrome) |
| Zheng et al, 2019 [ | China | Orthopedic (total joint arthroplasty) |
| Zhou et al, 2019 [ | China | Cancer (breast cancer surgery) |
| Zhou et al, 2020 [ | China | Cancer (breast cancer surgery) |
Figure 2Year of article publication.
Provider roles and examples of involvement in technology intervention used to facilitate hospital-to-home transitions (N=202).
| Provider role; providers, n (%) | Specific examples | Examples of provider role–technology interactions |
| Physician; 61 (30.2) | Community physician (eg, primary care physician, ambulatory physician, and community physician), hospital physician (eg, hospitalist, resident, and most responsible physician), and specialist (eg, cardiologist, surgeon, occupational physician, geriatrician, and pulmonologist) | Family physicians were alerted when patient data (eg, biometric or symptoms) fell outside predefined parameters and asked to visit or contact the patient [ |
| Nurse; 64 (31.7) | Specially trained nurse (trained in device use), research nurse, cancer nurse specialist, telemedicine nurse, rehabilitation nurse, nurse tutor, nurse practitioner, registered nurse, chronic obstructive pulmonary disease nurse, clinical nurse specialist, and community nurse | They reviewed all transmitted biometric and symptom data, flagged patients whose data fell outside the predefined parameters, and communicated with or assessed patients using communication technology [ |
| Clinician; 19 (9.4) | Discipline not specified | Clinicians were alerted when patient responses were outside predefined parameters, and they reviewed flagged responses [ |
| Allied health; 19 (9.4) | Occupational therapist, physiotherapist, social worker, and psychologist | Conducted telehealth consultations or sessions [ |
| Pharmacist; 18 (8.9) | Hospital or community pharmacist | Access information from other providers in the same facility or across facilities, settings or receive information from them and send information to them [ |
| Navigation-specific roles; 18 (8.9) | Advanced practice nurse or provider, care manager, care or program coordinator, care transition nurse, case manager, discharge planner or facilitator or discharge planning nurse, nurse navigator, post–acute care coordinator, system navigator, and transition coach | Provided 24-hour consultation, which was accessible to patients through technology [ |
| Other; 3 (1.5) | Physician’s assistant, unit supervisor, surgical team’s physician’s assistant | Used to communicate with other providers and send and receive information [ |
Summary of the lessons learned from implementation of digital health interventions.
| Challenge and description | Examples | |||
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| Participants’ physical, functional, and sensory function |
Low vision Hand tremor | |
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| Patients’ and providers’ lack of technical skills and experience |
Forgetting log-in information or not remembering to charge the device Accidentally disabling device features Low technology comfort | |
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| Device-related technical issues |
Internet connectivity issues Software updates affecting function Immaturity of the prototype | |
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| Fit and compatibility issues |
Poor fit with patients’ or providers’ routine Device incompatible with older devices Not integrated into organization’s electronic documentation system Identifying provider functions rather than their roles may enable the technology to accommodate differences among jurisdictions and changing scopes of practice | |
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| Patient-facing content |
Hypertext links were distracting and confusing Language too technical Offensive tone and complexity of the wording Symptom-reporting questions too specific or broad caused misunderstanding | |
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| Expectations of patient-initiated provider contact |
Not all participants were confident about the appropriate circumstances in which to contact the provider | |
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| Device notifications |
Excessive alerts caused “alert fatigue” and resulted in less attention being paid to the alert or ignoring it altogether | |
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| Enhancing functionality |
Address and improve multiple components of the transition process | |
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| Accessibility, adaptations, and customization |
Low-vision adaptations Adapt for participants with low technological literacy and no social support Self-directed apps Use of personal devices when possible and compatibility across multiple data and operating systems Provision of the device when participants do not have access to a personal device | |
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| Training |
Technical setup Training on technology use Engage caregivers in the intervention when possible | |
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| Fit with workflows, workloads, and buy-in |
Participants, family, caregivers, and providers should inform the technology design and how technology could be integrated into the day-to-day practices of all stakeholders Accounting for providers’ ethical, legal, and professional responsibilities | |
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| Recruitment and retention challenges |
Lack of interest High attrition | |
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| Small sample size |
Unable to explore the relationship between participants’ profiles, participants’ adherence and compliance to intervention or conduct subgroup analyses | |
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| Sampling bias |
Homogenous samples Inclusion limited to those with technology comfort or access | |
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| Missing data |
Impacting reliability of intervention results | |
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| Outcome measures |
Outcome measures such as rehospitalization and survival may not be sufficiently sensitive to determine intervention impact Single-blinded evaluator could introduce measurement error | |
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| Interventions across settings or institutions |
Cross-setting coordination challenges | |
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| Recruitment considerations |
Video of 10-to-15–minute duration describing the intervention (potential benefits and utility) during recruitment to reduce apprehension Consideration of low compliance rates within sample size calculations Comparing the characteristics of participants with those of individuals who declined can indicate selection bias and affect the intervention’s generalizability and acceptability | |
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| Outcomes |
Careful consideration of outcome measures (eg, objective or subjective) and end points | |
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| Missing data |
Begin intervention during hospitalization Schedule follow-ups during routine patient visits to minimize data lost during follow-up | |
Recommendations to guide the design and implementation of digital health interventions to facilitate hospital-to-home transitions.
| Recommendation | Description |
| Recommendation 1: align the design and delivery of digital health interventions to provider functions |
As roles and functions can differ based on several factors (eg, the organizations, jurisdiction, and care settings), technology functions should consider the roles and functions relevant to their target setting; alternatively, to increase generalizability, technology may need to support specific provider functions (ie, provider responsibilities) rather than outlining specific roles (ie, provider titles) Address multiple functions within transitional care, including functions supporting informational, management, and relational continuity of care Integration of technology with multiple organizations and across care settings Added provider functions with technology use should be minimal (eg, automated and self-directed functions could be integrated into interventions to reduce provider functions) Share functions related to technology use with patients and caregivers when possible Begin before or immediately after hospital admission and extend care into the community |
| Recommendation 2: design for, and test with, older adults |
To ensure that technology functions effectively meet the transitional care needs of older adults, digital health interventions should be designed for, and tested with, older adults Consider strategies to recruit and retain older adults with poor health Consider how technology functions may affect inequities Include caregivers, when possible, in digital health interventions because they play valuable roles in hospital-to-home transitions |
| Recommendation 3: examine multilevel outcomes |
Examine reasons for declining and dropping out of interventions Examine multilevel outcomes Provider-level outcomes may give insight into whether technology functions are perceived to support provider functions effectively Evaluate specific technology functions |