Zachary Pickell1, Albert J Sinusas2,3,4. 1. Department of Medicine (Section of Cardiovascular Medicine), Yale University School of Medicine, P.O. Box 208017, New Haven, CT, 06520, USA. 2. Department of Medicine (Section of Cardiovascular Medicine), Yale University School of Medicine, P.O. Box 208017, New Haven, CT, 06520, USA. Albert.Sinusas@yale.edu. 3. Department of Radiology & Biomedical Imaging, Yale University School of Medicine, New Haven, CT, USA. Albert.Sinusas@yale.edu. 4. Department of Biomedical Engineering, Yale University, New Haven, CT, USA. Albert.Sinusas@yale.edu.
Abstract
PURPOSE OF REVIEW: This review presents the current state of imaging approaches that enable real-time molecular imaging in the interventional suite and discusses the potential future use of integrated nuclear imaging and fluoroscopy for intraprocedural guidance in the evaluation and treatment of both cardiovascular and oncological diseases. RECENT FINDINGS: Although there are no commercially available real-time hybrid nuclear imaging devices that are approved for use in the interventional suite, prototype open gantry hybrid nuclear imaging and x-ray c-arm imaging systems and theranostic catheter for location radiotracer detection are currently undergoing development and testing by multiple groups. The integration of physiological and molecular targeted nuclear imaging for real-time delivery of targeted theranostics in the interventional laboratory may enable more personalized care for a wide variety of cardiovascular procedures and improve patient outcomes.
PURPOSE OF REVIEW: This review presents the current state of imaging approaches that enable real-time molecular imaging in the interventional suite and discusses the potential future use of integrated nuclear imaging and fluoroscopy for intraprocedural guidance in the evaluation and treatment of both cardiovascular and oncological diseases. RECENT FINDINGS: Although there are no commercially available real-time hybrid nuclear imaging devices that are approved for use in the interventional suite, prototype open gantry hybrid nuclear imaging and x-ray c-arm imaging systems and theranostic catheter for location radiotracer detection are currently undergoing development and testing by multiple groups. The integration of physiological and molecular targeted nuclear imaging for real-time delivery of targeted theranostics in the interventional laboratory may enable more personalized care for a wide variety of cardiovascular procedures and improve patient outcomes.
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