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Literature DB >> 3960133

DNA bending at adenine . thymine tracts.

Abstract

Intrinsic bending of DNA molecules results from local structural polymorphism in regions of homopolymeric dA . dT which are at least 4 base pairs long; the A . T tracts must be repeated in phase with the helix screw. Bending, in the direction of base-pair tilt rather than roll, occurs at the junctions between the A . T tract and adjacent B-DNA, with a larger angle at the 3' than at the 5' end of the A tract.

Entities: Chemical

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Year: 1986 PMID： 3960133 DOI： 10.1038/320501a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

358 in total

1. Functional interactions between a phage histone-like protein and a transcriptional factor in regulation of phi29 early-late transcriptional switch.

Authors: M Elías-Arnanz; M Salas
Journal: Genes Dev Date: 1999-10-01 Impact factor: 11.361

2. Bacterial promoter architecture: subsite structure of UP elements and interactions with the carboxy-terminal domain of the RNA polymerase alpha subunit.

Authors: S T Estrem; W Ross; T Gaal; Z W Chen; W Niu; R H Ebright; R L Gourse
Journal: Genes Dev Date: 1999-08-15 Impact factor: 11.361

10. AbrB, a regulator of gene expression in Bacillus, interacts with the transcription initiation regions of a sporulation gene and an antibiotic biosynthesis gene.

Authors: J B Robertson; M Gocht; M A Marahiel; P Zuber
Journal: Proc Natl Acad Sci U S A Date: 1989-11 Impact factor: 11.205

DNA bending at adenine . thymine tracts.

1. Functional interactions between a phage histone-like protein and a transcriptional factor in regulation of phi29 early-late transcriptional switch.

2. Bacterial promoter architecture: subsite structure of UP elements and interactions with the carboxy-terminal domain of the RNA polymerase alpha subunit.

3. Highly mutagenic replication by DNA polymerase V (UmuC) provides a mechanistic basis for SOS untargeted mutagenesis.

4. Fine structure of E. coli RNA polymerase-promoter interactions: alpha subunit binding to the UP element minor groove.

5. Poly(dA.dT) sequences exist as rigid DNA structures in nucleosome-free yeast promoters in vivo.

6. High-throughput approach for detection of DNA bending and flexibility based on cyclization.

7. Structural origins of adenine-tract bending.

8. Sequence-dependent DNA curvature and flexibility from scanning force microscopy images.

9. Mutational analysis of the histidine operon promoter of Salmonella typhimurium.

10. AbrB, a regulator of gene expression in Bacillus, interacts with the transcription initiation regions of a sporulation gene and an antibiotic biosynthesis gene.