Lorenzo Ismael Perez-Sanchez1, Julia Gutierrez-Vazquez2, Maria Satrustegui-Lapetra3, Francisco Ferreira-Manuel2, Juan Jose Arevalo-Manso4, Juan Jesus Gomez-Herrera2, Juan Jose Criado-Alvarez5,6. 1. Department of Radiology, Complejo Asistencial de Segovia, C/Luis Erik Clavería Neurólogo, s/n, 40002, Segovia, Spain. lorenzoips@gmail.com. 2. Department of Radiology, Complejo Asistencial de Segovia, C/Luis Erik Clavería Neurólogo, s/n, 40002, Segovia, Spain. 3. Department of Ophthalmology, Complejo Asistencial de Segovia, Segovia, Spain. 4. Healthcare Research Advisory, CSIF-Sanidad, Complejo Asistencial de Segovia, Segovia, Spain. 5. Talavera de La Reina Integrated Healthcare Area, Servicio de Salud de Castilla La Mancha, Talavera de La Reina, Toledo, Spain. 6. Department of Medical Sciences, School of Health Science, Universidad de Castilla La Mancha, Talavera de La Reina, Toledo, Spain.
Abstract
PURPOSE: To evaluate the reliability and agreement between Fully Refocused Steady-State magnetic resonance sequences (FRSS) and the IOLMaster® 500 optical biometer for measuring anterior chamber depth (ACD) and axial length (AL). METHODS: In a sample of 32 healthy volunteers, separate observers measured the ACD and AL of both eyes using both techniques (inter-method) and through repeated FRSS measurements (interobserver) and by the same observer (intraobserver). We employed the Bland-Altman method to determine the agreement between FRSS and partial coherence interferometry (using the IOLMaster®) and the interobserver and intraobserver variability, providing the limits of agreement (LoA, or mean difference ± 1.96 SD). Correlation coefficients and intraclass correlation coefficients were also provided. RESULTS: For ACD measurements with FRSS in pseudo-color scale, we obtained an LoA of 0.016 ± 0.266 mm compared with partial coherence interferometry. For AL with FRSS in greyscale, the LoA was 0.019 ± 0.383 mm. Maximum interobserver variability showed a - 0.036 ± 0.247 mm LoA for ACD with FRSS in pseudo-color scale. Maximum intraobserver variability was 0.000 ± 0.157 mm LoA for AL with FRSS in greyscale. CONCLUSIONS: ACD and AL measurements using FRSS sequencing present high LoA and reliability when compared with partial coherence interferometry using the IOLMaster® 500. The results were better for FRSS in pseudo-color scale in ACD determination and for FRSS in greyscale in AL determination. FRSS would not be recommended for IOL power calculation due to variability of AL measurement.
PURPOSE: To evaluate the reliability and agreement between Fully Refocused Steady-State magnetic resonance sequences (FRSS) and the IOLMaster® 500 optical biometer for measuring anterior chamber depth (ACD) and axial length (AL). METHODS: In a sample of 32 healthy volunteers, separate observers measured the ACD and AL of both eyes using both techniques (inter-method) and through repeated FRSS measurements (interobserver) and by the same observer (intraobserver). We employed the Bland-Altman method to determine the agreement between FRSS and partial coherence interferometry (using the IOLMaster®) and the interobserver and intraobserver variability, providing the limits of agreement (LoA, or mean difference ± 1.96 SD). Correlation coefficients and intraclass correlation coefficients were also provided. RESULTS: For ACD measurements with FRSS in pseudo-color scale, we obtained an LoA of 0.016 ± 0.266 mm compared with partial coherence interferometry. For AL with FRSS in greyscale, the LoA was 0.019 ± 0.383 mm. Maximum interobserver variability showed a - 0.036 ± 0.247 mm LoA for ACD with FRSS in pseudo-color scale. Maximum intraobserver variability was 0.000 ± 0.157 mm LoA for AL with FRSS in greyscale. CONCLUSIONS: ACD and AL measurements using FRSS sequencing present high LoA and reliability when compared with partial coherence interferometry using the IOLMaster® 500. The results were better for FRSS in pseudo-color scale in ACD determination and for FRSS in greyscale in AL determination. FRSS would not be recommended for IOL power calculation due to variability of AL measurement.
Entities:
Keywords:
Anterior chamber; Eye axial length; Interferometry; Magnetic resonance imaging
Authors: Govind B Chavhan; Paul S Babyn; Bhavin G Jankharia; Hai-Ling M Cheng; Manohar M Shroff Journal: Radiographics Date: 2008 Jul-Aug Impact factor: 5.333