Literature DB >> 33472904

A Novel Point Mutation in the N Gene of SARS-CoV-2 May Affect the Detection of the Virus by Reverse Transcription-Quantitative PCR.

Mohammad Rubayet Hasan1,2, Sathyavathi Sundararaju3, Chidambaram Manickam3, Faheem Mirza3, Hamad Al-Hail3, Stephan Lorenz3, Patrick Tang3,2.   

Abstract

Entities:  

Keywords:  COVID-19; N gene; RT-qPCR; SARS-CoV-2; point mutation

Year:  2021        PMID： 33472904     DOI： 10.1128/JCM.03278-20

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


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  30 in total

1.  Detection of SARS-CoV-2 VOC-Omicron using commercial sample-to-answer real-time RT-PCR platforms and melting curve-based SNP assays.

Authors:  Brian H M Sit; Kathy Hiu Laam Po; Yuk-Yam Cheung; Alan K L Tsang; Patricia K L Leung; J Zheng; Alison Y T Lam; Edman T K Lam; Ken H L Ng; Rickjason C W Chan
Journal:  J Clin Virol Plus       Date:  2022-06-17

2.  Nosocomial severe acute respiratory coronavirus virus 2 (SARS-CoV-2) transmission arising from a case of N-gene dropout on reverse-transcription polymerase chain reaction (RT-PCR) testing.

Authors:  Liang En Ian Wee; Karrie Kwan-Ki Ko; Edwin Philip Conceicao; May Kyawt Aung; Myat Oo Aung; Yong Yang; Shalvi Arora; Chayaporn Suphavilai; Indumathi Venkatachalam
Journal:  Infect Control Hosp Epidemiol       Date:  2022-07-01       Impact factor: 6.520

3.  Single base mutations in the nucleocapsid gene of SARS-CoV-2 affects amplification efficiency of sequence variants and may lead to assay failure.

Authors:  Nathaniel Storey; Julianne R Brown; Rui P A Pereira; Denise M O'Sullivan; Jim F Huggett; Rachel Williams; Judith Breuer; Kathryn A Harris
Journal:  J Clin Virol Plus       Date:  2021-08-15

4.  Endemic SARS-CoV-2 Polymorphisms Can Cause a Higher Diagnostic Target Failure Rate than Estimated by Aggregate Global Sequencing Data.

Authors:  Daniel D Rhoads; David Plunkett; Joy Nakitandwe; Andrew Dempsey; Zheng Jin Tu; Gary W Procop; David Bosler; Brian P Rubin; Michael J Loeffelholz; Jay E Brock
Journal:  J Clin Microbiol       Date:  2021-07-19       Impact factor: 5.948

Review 5.  Tools and Techniques for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)/COVID-19 Detection.

Authors:  Seyed Hamid Safiabadi Tali; Jason J LeBlanc; Zubi Sadiq; Oyejide Damilola Oyewunmi; Carolina Camargo; Bahareh Nikpour; Narges Armanfard; Selena M Sagan; Sana Jahanshahi-Anbuhi
Journal:  Clin Microbiol Rev       Date:  2021-05-12       Impact factor: 26.132

6.  Nucleocapsid (N) Gene Mutations of SARS-CoV-2 Can Affect Real-Time RT-PCR Diagnostic and Impact False-Negative Results.

Authors:  Jéssika Cristina Chagas Lesbon; Mirele Daiana Poleti; Elisângela Chicaroni de Mattos Oliveira; José Salvatore Leister Patané; Luan Gaspar Clemente; Vincent Louis Viala; Gabriela Ribeiro; Marta Giovanetti; Luiz Carlos Junior de Alcantara; Olivia Teixeira; Maria Cristina Nonato; Loyze Paola Oliveira de Lima; Antonio Jorge Martins; Claudia Renata Dos Santos Barros; Elaine Cristina Marqueze; Jardelina de Souza Todão Bernardino; Debora Botequio Moretti; Ricardo Augusto Brassaloti; Raquel de Lello Rocha Campos Cassano; Pilar Drummond Sampaio Correa Mariani; Svetoslav Nanev Slavov; Rafael Bezerra Dos Santos; Evandra Strazza Rodrigues; Elaine Vieira Santos; Josiane Serrano Borges; Debora Glenda Lima de La Roque; Joao Paulo Kitajima; Bibiana Santos; Patricia Akemi Assato; Felipe Allan da Silva da Costa; Cecilia Artico Banho; Livia Sacchetto; Marilia Mazzi Moraes; Melissa Palmieri; Fabiana Erica Vilanova da Silva; Rejane Maria Tommasini Grotto; Jayme A Souza-Neto; Mauricio Lacerda Nogueira; Luiz Lehman Coutinho; Rodrigo Tocantins Calado; Raul Machado Neto; Dimas Tadeu Covas; Simone Kashima; Maria Carolina Elias; Sandra Coccuzzo Sampaio; Heidge Fukumasu
Journal:  Viruses       Date:  2021-12-10       Impact factor: 5.818

7.  A short plus long-amplicon based sequencing approach improves genomic coverage and variant detection in the SARS-CoV-2 genome.

Authors:  Carlos Arana; Chaoying Liang; Matthew Brock; Bo Zhang; Jinchun Zhou; Li Chen; Brandi Cantarel; Jeffrey SoRelle; Lora V Hooper; Prithvi Raj
Journal:  PLoS One       Date:  2022-01-13       Impact factor: 3.240

Review 8.  The Emerging Concern and Interest SARS-CoV-2 Variants.

Authors:  Edyta Janik; Marcin Niemcewicz; Marcin Podogrocki; Ireneusz Majsterek; Michal Bijak
Journal:  Pathogens       Date:  2021-05-21

9.  Lack of N2-gene amplification on the Cepheid Xpert Xpress SARS-CoV-2 assay and potential novel causative mutations: A case series from Auckland, New Zealand.

Authors:  Shivani Fox-Lewis; Andrew Fox-Lewis; Jay Harrower; Richard Chen; Jing Wang; Joep de Ligt; Gary McAuliffe; Susan Taylor; Erasmus Smit
Journal:  IDCases       Date:  2021-07-24

10.  Identification of Hotspot Mutations in the N Gene of SARS-CoV-2 in Russian Clinical Samples That May Affect the Detection by Reverse Transcription-PCR.

Authors:  Sergei A Kiryanov; Tatiana A Levina; Maria V Konopleva; Anatoly P Suslov
Journal:  Diagnostics (Basel)       Date:  2022-01-08
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