Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Elasticizing tissues for reversible shape transformation and accelerated molecular labeling.

Literature DB >> 32424271

Elasticizing tissues for reversible shape transformation and accelerated molecular labeling.

Taeyun Ku^1,2,3, Webster Guan⁴, Nicholas B Evans^1,2, Chang Ho Sohn^1,2, Alexandre Albanese¹, Joon-Goon Kim⁵, Matthew P Frosch⁶, Kwanghun Chung^{7,8,9,10,11,12,13}.

Abstract

We developed entangled link-augmented stretchable tissue-hydrogel (ELAST), a technology that transforms tissues into elastic hydrogels to enhance macromolecular accessibility and mechanical stability simultaneously. ELASTicized tissues are highly stretchable and compressible, which enables reversible shape transformation and faster delivery of probes into intact tissue specimens via mechanical thinning. This universal platform may facilitate rapid and scalable molecular phenotyping of large-scale biological systems, such as human organs.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2020 PMID： 32424271 PMCID： PMC8056749 DOI： 10.1038/s41592-020-0823-y

Source DB: PubMed Journal: Nat Methods ISSN： 1548-7091 Impact factor: 28.547

21 in total

1. Scale: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain.

Authors: Hiroshi Hama; Hiroshi Kurokawa; Hiroyuki Kawano; Ryoko Ando; Tomomi Shimogori; Hisayori Noda; Kiyoko Fukami; Asako Sakaue-Sawano; Atsushi Miyawaki
Journal: Nat Neurosci Date: 2011-08-30 Impact factor: 24.884

Review 2. Advances in engineering hydrogels.

Authors: Yu Shrike Zhang; Ali Khademhosseini
Journal: Science Date: 2017-05-05 Impact factor: 47.728

3. Shrinkage-mediated imaging of entire organs and organisms using uDISCO.

Authors: Chenchen Pan; Ruiyao Cai; Francesca Paola Quacquarelli; Alireza Ghasemigharagoz; Athanasios Lourbopoulos; Paweł Matryba; Nikolaus Plesnila; Martin Dichgans; Farida Hellal; Ali Ertürk
Journal: Nat Methods Date: 2016-08-22 Impact factor: 28.547

4. Quantifying the impact of molecular defects on polymer network elasticity.

Authors: Mingjiang Zhong; Rui Wang; Ken Kawamoto; Bradley D Olsen; Jeremiah A Johnson
Journal: Science Date: 2016-09-16 Impact factor: 47.728

5. Optical imaging. Expansion microscopy.

Authors: Fei Chen; Paul W Tillberg; Edward S Boyden
Journal: Science Date: 2015-01-15 Impact factor: 47.728

6. Whole-Body Profiling of Cancer Metastasis with Single-Cell Resolution.

Authors: Shimpei I Kubota; Kei Takahashi; Jun Nishida; Yasuyuki Morishita; Shogo Ehata; Kazuki Tainaka; Kohei Miyazono; Hiroki R Ueda
Journal: Cell Rep Date: 2017-07-05 Impact factor: 9.423

Review 7. Tissue clearing and its applications in neuroscience.

Authors: Hiroki R Ueda; Ali Ertürk; Kwanghun Chung; Viviana Gradinaru; Alain Chédotal; Pavel Tomancak; Philipp J Keller
Journal: Nat Rev Neurosci Date: 2020-02 Impact factor: 34.870

8. MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling.

Authors: N Mellios; D A Feldman; S D Sheridan; J P K Ip; S Kwok; S K Amoah; B Rosen; B A Rodriguez; B Crawford; R Swaminathan; S Chou; Y Li; M Ziats; C Ernst; R Jaenisch; S J Haggarty; M Sur
Journal: Mol Psychiatry Date: 2017-04-25 Impact factor: 15.992

9. Scalable and Isotropic Expansion of Tissues with Simply Tunable Expansion Ratio.

Authors: Han-Eol Park; Dongkil Choi; Ji Su Park; Changgon Sim; Sohyun Park; Sunah Kang; Hyunsoo Yim; Myungsun Lee; Jaeyoun Kim; Jinyoung Pac; Kunsoo Rhee; Junho Lee; Yunjong Lee; Yan Lee; Sung-Yon Kim
Journal: Adv Sci (Weinh) Date: 2019-09-30 Impact factor: 16.806

10. Nanoscale imaging of RNA with expansion microscopy.

Authors: Fei Chen; Asmamaw T Wassie; Allison J Cote; Anubhav Sinha; Shahar Alon; Shoh Asano; Evan R Daugharthy; Jae-Byum Chang; Adam Marblestone; George M Church; Arjun Raj; Edward S Boyden
Journal: Nat Methods Date: 2016-07-04 Impact factor: 28.547

17 in total

1. TISSUE CLEARING.

Authors: Douglas S Richardson; Webster Guan; Katsuhiko Matsumoto; Chenchen Pan; Kwanghun Chung; Ali Ertürk; Hiroki R Ueda; Jeff W Lichtman
Journal: Nat Rev Methods Primers Date: 2021-12-16

Review 2. Scalable tissue labeling and clearing of intact human organs.

Authors: Hongcheng Mai; Zhouyi Rong; Shan Zhao; Ruiyao Cai; Hanno Steinke; Ingo Bechmann; Ali Ertürk
Journal: Nat Protoc Date: 2022-07-20 Impact factor: 17.021

Review 3. Multispectral confocal 3D imaging of intact healthy and tumor tissue using mLSR-3D.

Authors: Ravian L van Ineveld; Raphaël Collot; Mario Barrera Román; Anna Pagliaro; Nils Bessler; Hendrikus C R Ariese; Michiel Kleinnijenhuis; Marcel Kool; Maria Alieva; Susana M Chuva de Sousa Lopes; Ellen J Wehrens; Anne C Rios
Journal: Nat Protoc Date: 2022-09-30 Impact factor: 17.021

Review 4. Nanoscale fluorescence imaging of biological ultrastructure via molecular anchoring and physical expansion.

Authors: Wei Wang; Yat Ho Chan; SoYoung Kwon; Jamuna Tandukar; Ruixuan Gao
Journal: Nano Converg Date: 2022-07-09

5. A simple optical tissue clearing pipeline for 3D vasculature imaging of the mediastinal organs in mice.

Authors: Quanchao Sun; Picascia Tiziana; Arif Ul Maula Khan; Vincent Heuveline; Norbert Gretz
Journal: Int J Exp Pathol Date: 2021-10-06 Impact factor: 2.793

Review 6. 3D imaging for driving cancer discovery.

Authors: Ravian L van Ineveld; Esmée J van Vliet; Ellen J Wehrens; Maria Alieva; Anne C Rios
Journal: EMBO J Date: 2022-04-11 Impact factor: 14.012

7. Large-scale, cell-resolution volumetric mapping allows layer-specific investigation of human brain cytoarchitecture.

Authors: Irene Costantini; Giacomo Mazzamuto; Matteo Roffilli; Annunziatina Laurino; Filippo Maria Castelli; Mattia Neri; Giovanni Lughi; Andrea Simonetto; Erica Lazzeri; Luca Pesce; Christophe Destrieux; Ludovico Silvestri; Valerio Conti; Renzo Guerrini; Francesco Saverio Pavone
Journal: Biomed Opt Express Date: 2021-05-27 Impact factor: 3.732