Literature DB >> 31452053

Translation of Patient-Reported Outcomes in Oncology Clinical Trials to Everyday Practice.

Srinivas Joga Ivatury1,2, Hannah W Hazard-Jenkins3, Gabriel A Brooks4,5, Nadine J McCleary6, Sandra L Wong4,5, Deborah Schrag6.   

Abstract

PURPOSE: Clinical trials in oncology evaluating the effects of patient-reported outcomes (PRO) collection have found that monitoring of symptoms with PROs is associated with improved clinical care through reduced acute care utilization and decreased patient symptom burden. This educational review will evaluate strategies for systematic PRO integration into everyday oncology clinical practice.
METHODS: We outline key considerations for using PROs in clinical practice, highlighting evidence from published studies. We also discuss the benefits and challenges of PRO implementation in oncology.
RESULTS: Implementing PRO collection in clinical practice can improve care delivery and facilitate patient-centered clinical research. Considerations for using PROs in clinical practice include choice of instrument, method of delivery, and frequency of query. Challenges with implementing systematic PRO collection include the costs and resources needed for implementation, impact on clinical workflow, and controlling/monitoring physician burnout.
CONCLUSIONS: While challenges exist in terms of financial resources and staff participation/burnout, patient-reported outcomes in clinical practice provide a number of benefits, including symptom monitoring, clinical research, and potential real-time personalized clinical-decision support.

Entities:  

Mesh:

Year:  2019        PMID: 31452053      PMCID: PMC6925618          DOI: 10.1245/s10434-019-07749-2

Source DB:  PubMed          Journal:  Ann Surg Oncol        ISSN: 1068-9265            Impact factor:   5.344


  21 in total

Review 1.  Impact of consumer health informatics applications.

Authors:  M Christopher Gibbons; Renee F Wilson; Lipika Samal; Christoph U Lehman; Kay Dickersin; Harold P Lehmann; Hanan Aboumatar; Joseph Finkelstein; Erica Shelton; Ritu Sharma; Eric B Bass
Journal:  Evid Rep Technol Assess (Full Rep)       Date:  2009-10

2.  Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT): a randomized trial.

Authors:  James N Weinstein; Tor D Tosteson; Jon D Lurie; Anna N A Tosteson; Brett Hanscom; Jonathan S Skinner; William A Abdu; Alan S Hilibrand; Scott D Boden; Richard A Deyo
Journal:  JAMA       Date:  2006-11-22       Impact factor: 56.272

3.  Supporting clinical practice decisions with real-time patient-reported outcomes.

Authors:  Ethan Basch; Amy P Abernethy
Journal:  J Clin Oncol       Date:  2011-01-31       Impact factor: 44.544

4.  Comparison of interactive voice response, patient mailing, and mailed registry to encourage screening for osteoporosis: a randomized controlled trial.

Authors:  L Heyworth; K Kleinman; S Oddleifson; L Bernstein; J Frampton; M Lehrer; K Salvato; T W Weiss; S R Simon; M Connelly
Journal:  Osteoporos Int       Date:  2014-02-25       Impact factor: 4.507

5.  Patients report improvements in continuity of care when quality of life assessments are used routinely in oncology practice: secondary outcomes of a randomised controlled trial.

Authors:  Galina Velikova; Ada Keding; Clare Harley; Kim Cocks; Laura Booth; Adam B Smith; Penny Wright; Peter J Selby; Julia M Brown
Journal:  Eur J Cancer       Date:  2010-06-01       Impact factor: 9.162

6.  The European Organization for Research and Treatment of Cancer. Approach to quality of life assessment: guidelines for developing questionnaire modules. EORTC Study Group on Quality of Life.

Authors:  M A Sprangers; A Cull; K Bjordal; M Groenvold; N K Aaronson
Journal:  Qual Life Res       Date:  1993-08       Impact factor: 4.147

7.  Symptom Monitoring With Patient-Reported Outcomes During Routine Cancer Treatment: A Randomized Controlled Trial.

Authors:  Ethan Basch; Allison M Deal; Mark G Kris; Howard I Scher; Clifford A Hudis; Paul Sabbatini; Lauren Rogak; Antonia V Bennett; Amylou C Dueck; Thomas M Atkinson; Joanne F Chou; Dorothy Dulko; Laura Sit; Allison Barz; Paul Novotny; Michael Fruscione; Jeff A Sloan; Deborah Schrag
Journal:  J Clin Oncol       Date:  2015-12-07       Impact factor: 44.544

8.  Measuring quality of life in routine oncology practice improves communication and patient well-being: a randomized controlled trial.

Authors:  Galina Velikova; Laura Booth; Adam B Smith; Paul M Brown; Pamela Lynch; Julia M Brown; Peter J Selby
Journal:  J Clin Oncol       Date:  2004-02-15       Impact factor: 44.544

9.  Allocation of Physician Time in Ambulatory Practice: A Time and Motion Study in 4 Specialties.

Authors:  Christine Sinsky; Lacey Colligan; Ling Li; Mirela Prgomet; Sam Reynolds; Lindsey Goeders; Johanna Westbrook; Michael Tutty; George Blike
Journal:  Ann Intern Med       Date:  2016-09-06       Impact factor: 25.391

10.  Health App Use Among US Mobile Phone Owners: A National Survey.

Authors:  Paul Krebs; Dustin T Duncan
Journal:  JMIR Mhealth Uhealth       Date:  2015-11-04       Impact factor: 4.773

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  5 in total

1.  ASO Author Reflections: Patient-Reported Outcomes-Bench to Bedside.

Authors:  Srinivas Joga Ivatury; Sandra L Wong; Deborah Schrag
Journal:  Ann Surg Oncol       Date:  2019-11-18       Impact factor: 5.344

2.  Prioritizing the Patient Perspective in Oncologic Surgery.

Authors:  Nikhil Panda; Alex B Haynes
Journal:  Ann Surg Oncol       Date:  2019-08-26       Impact factor: 5.344

3.  Creation and Psychometric Validation of the Sexual Minorities and Prostate Cancer Scale (SMACS) in Sexual Minority Patients-The Restore-2 Study.

Authors:  Elizabeth J Polter; Nidhi Kohli; B R Simon Rosser; Kristine M C Talley; Christopher W Wheldon; Chris J Hoefer; Morgan Wright; Ryan Haggart; Darry Mitteldorf; Gudrun Kilian; Badrinath R Konety; Michael W Ross; William West
Journal:  J Sex Med       Date:  2022-02-04       Impact factor: 3.802

4.  Developing and Sustaining an Effective and Resilient Oncology Careforce: Opportunities for Action.

Authors:  Samuel U Takvorian; Erin Balogh; Sharyl Nass; Virginia L Valentin; Lori Hoffman-Hogg; Randall A Oyer; Robert W Carlson; Neal J Meropol; Lisa Kennedy Sheldon; Lawrence N Shulman
Journal:  J Natl Cancer Inst       Date:  2020-07-01       Impact factor: 13.506

Review 5.  A review of patient-reported outcomes used for regulatory approval of oncology medicinal products in the European Union between 2017 and 2020.

Authors:  Maria Manuel Teixeira; Fábio Cardoso Borges; Paula Sousa Ferreira; João Rocha; Bruno Sepodes; Carla Torre
Journal:  Front Med (Lausanne)       Date:  2022-08-12
  5 in total

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