Literature DB >> 31278582

MRI identifies biochemical alterations of intervertebral discs in patients with low back pain and radiculopathy.

Tina Pulickal1, Johannes Boos2, Markus Konieczny3, Lino Morris Sawicki1, Anja Müller-Lutz1, Bernd Bittersohl3, Joachim Gerß4, Markus Eichner1, Hans-Jörg Wittsack1, Gerald Antoch1, Christoph Schleich1.   

Abstract

KEY POINTS: • Molecular intervertebral disc damage was associated with LBP and radiculopathy.• Patients with radiculopathy and LBP demonstrated a depletion of gagCEST values compared with healthy controls.• GagCEST imaging may be a non-invasive tool for investigation of degeneration processes of lumbar intervertebral discs (IVDs). GagCEST imaging may be an imaging biomarker for biochemical IVD alterations.

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Year:  2019        PMID： 31278582     DOI： 10.1007/s00330-019-06305-6

Source DB:  PubMed          Journal:  Eur Radiol        ISSN： 0938-7994            Impact factor:   5.315


  10 in total

1.  Introduction: disc degeneration: summary.

Authors:  Howard S An; Paul A Anderson; Victor M Haughton; James C Iatridis; James D Kang; Jeffrey C Lotz; Raghu N Natarajan; Theodore R Oegema; Peter Roughley; Lori A Setton; Jill P Urban; Tapio Videman; Gunnar B J Andersson; James N Weinstein
Journal:  Spine (Phila Pa 1976)       Date:  2004-12-01       Impact factor: 3.468

Review 2.  Pathophysiology of the intervertebral disc and the challenges for MRI.

Authors:  Jill P G Urban; C Peter Winlove
Journal:  J Magn Reson Imaging       Date:  2007-02       Impact factor: 4.813

3.  Delayed onset of persistent discogenic axial and radiating pain after a single-level lumbar intervertebral disc injury in mice.

Authors:  Magali Millecamps; Laura S Stone
Journal:  Pain       Date:  2018-09       Impact factor: 6.961

4.  Endplate Defect Is Heritable, Associated With Low Back Pain and Triggers Intervertebral Disc Degeneration: A Longitudinal Study From TwinsUK.

Authors:  Sabrina Munir; Maxim B Freidin; Marinko Rade; Juhani Määttä; Gregory Livshits; Frances M K Williams
Journal:  Spine (Phila Pa 1976)       Date:  2018-11-01       Impact factor: 3.468

5.  Comparison of B0 versus B0 and B1 field inhomogeneity correction for glycosaminoglycan chemical exchange saturation transfer imaging.

Authors:  Anja Müller-Lutz; Alexandra Ljimani; Julia Stabinska; Moritz Zaiss; Johannes Boos; Hans-Jörg Wittsack; Christoph Schleich
Journal:  MAGMA       Date:  2018-05-14       Impact factor: 2.310

6.  Gadolinium Deposition in Human Brain Tissues after Contrast-enhanced MR Imaging in Adult Patients without Intracranial Abnormalities.

Authors:  Robert J McDonald; Jennifer S McDonald; David F Kallmes; Mark E Jentoft; Michael A Paolini; David L Murray; Eric E Williamson; Laurence J Eckel
Journal:  Radiology       Date:  2017-06-27       Impact factor: 11.105

7.  Associations between back pain history and lumbar MRI findings.

Authors:  Tapio Videman; Michele C Battié; Laura E Gibbons; Kenneth Maravilla; Hannu Manninen; Jaakko Kaprio
Journal:  Spine (Phila Pa 1976)       Date:  2003-03-15       Impact factor: 3.468

8.  Burned-out discs stop hurting: fact or fiction?

Authors:  Tom Bendix; Per Kjaer; Lars Korsholm
Journal:  Spine (Phila Pa 1976)       Date:  2008-12-01       Impact factor: 3.468

9.  The global burden of low back pain: estimates from the Global Burden of Disease 2010 study.

Authors:  Damian Hoy; Lyn March; Peter Brooks; Fiona Blyth; Anthony Woolf; Christopher Bain; Gail Williams; Emma Smith; Theo Vos; Jan Barendregt; Chris Murray; Roy Burstein; Rachelle Buchbinder
Journal:  Ann Rheum Dis       Date:  2014-03-24       Impact factor: 19.103

10.  Glycosaminoglycan Chemical Exchange Saturation Transfer of Lumbar Intervertebral Discs in Healthy Volunteers.

Authors:  Christoph Schleich; Anja Müller-Lutz; Markus Eichner; Benjamin Schmitt; Felix Matuschke; Bernd Bittersohl; Christoph Zilkens; Hans-Jörg Wittsack; Gerald Antoch; Falk Miese
Journal:  Spine (Phila Pa 1976)       Date:  2016-01       Impact factor: 3.468
  10 in total
  9 in total

Review 1.  Proper animal experimental designs for preclinical research of biomaterials for intervertebral disc regeneration.

Authors:  Yizhong Peng; Xiangcheng Qing; Hongyang Shu; Shuo Tian; Wenbo Yang; Songfeng Chen; Hui Lin; Xiao Lv; Lei Zhao; Xi Chen; Feifei Pu; Donghua Huang; Xu Cao; Zengwu Shao
Journal:  Biomater Transl       Date:  2021-06-28

2.  Danshen Attenuates Intervertebral Disc Degeneration via Antioxidation in SD Rats.

Authors:  Rongqing Qin; Shouqian Dai; Xing Zhang; Hongpeng Liu; Bing Zhou; Pin Zhou; Chuanliang Hu
Journal:  Oxid Med Cell Longev       Date:  2020-12-22       Impact factor: 6.543

3.  Salvianolic Acid B Protects Intervertebral Discs from Oxidative Stress-Induced Degeneration via Activation of the JAK2/STAT3 Signaling Pathway.

Authors:  Shouqian Dai; Ting Liang; Xiu Shi; Zongping Luo; Huilin Yang
Journal:  Oxid Med Cell Longev       Date:  2021-02-12       Impact factor: 6.543

4.  Non-Specific Low Back Pain and Lumbar Radiculopathy: Comparison of Morphologic and Compositional MRI as Assessed by gagCEST Imaging at 3T.

Authors:  Miriam Frenken; Sven Nebelung; Christoph Schleich; Anja Müller-Lutz; Karl Ludger Radke; Benedikt Kamp; Matthias Boschheidgen; Lena Wollschläger; Bernd Bittersohl; Gerald Antoch; Markus R Konieczny; Daniel B Abrar
Journal:  Diagnostics (Basel)       Date:  2021-02-26

5.  Detection of early cartilage degeneration in the tibiotalar joint using 3 T gagCEST imaging: a feasibility study.

Authors:  Daniel B Abrar; Christoph Schleich; Sven Nebelung; Anja Müller-Lutz; Karl Ludger Radke; Miriam Frenken; Julia Stabinska; Alexandra Ljimani; Hans-Jörg Wittsack; Gerald Antoch; Bernd Bittersohl; Tobias Hesper
Journal:  MAGMA       Date:  2020-07-28       Impact factor: 2.310

6.  An end-to-end AI-based framework for automated discovery of rapid CEST/MT MRI acquisition protocols and molecular parameter quantification (AutoCEST).

Authors:  Or Perlman; Bo Zhu; Moritz Zaiss; Matthew S Rosen; Christian T Farrar
Journal:  Magn Reson Med       Date:  2022-01-28       Impact factor: 3.737

7.  Scientific literature landscape analysis of researches on oxidative stress in intervertebral disc degeneration in web of science.

Authors:  Yunzhong Cheng; Honghao Yang; Yong Hai; Lijin Zhou
Journal:  Front Mol Biosci       Date:  2022-08-11

Review 8.  Imaging Evaluation of Intervertebral Disc Degeneration and Painful Discs-Advances and Challenges in Quantitative MRI.

Authors:  Shota Tamagawa; Daisuke Sakai; Hidetoshi Nojiri; Masato Sato; Muneaki Ishijima; Masahiko Watanabe
Journal:  Diagnostics (Basel)       Date:  2022-03-14

9.  Visualizing patterns of intervertebral disc damage with dual-energy computed tomography: assessment of diagnostic accuracy in an ex vivo spine biophantom.

Authors:  Julian Pohlan; Carsten Stelbrink; Niklas Tuttle; Felix Kubicka; Ho Jung Kwon; Paul Jahnke; Friedemann Goehler; Olivia Kershaw; Achim D Gruber; Matthias Pumberger; Torsten Diekhoff
Journal:  Acta Radiol       Date:  2021-07-04       Impact factor: 1.701
  9 in total

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