| Literature DB >> 31120968 |
Imali T Hettiarachchi1, Samer Hanoun1, Darius Nahavandi1, Saeid Nahavandi1.
Abstract
BACKGROUND: Optical measurement techniques and recent advances in wearable technology have made heart rate (HR) sensing simpler and more affordable.Entities:
Mesh:
Year: 2019 PMID: 31120968 PMCID: PMC6532910 DOI: 10.1371/journal.pone.0217288
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Participants’ characteristics.
BMI: body mass index.
| Demographics | Males | Females | ||
|---|---|---|---|---|
| Mean (SD) | Range | Mean (SD) | Range | |
| Age (years) | 26 (4.8) | 21–33 | 30 (5.48) | 21–38 |
| Height (cm) | 176.8(5.77) | 168–187 | 164.09(9.47) | 150–175 |
| Weight (kg) | 76.33(10.29) | 60–97 | 55.91(10.77) | 44–76 |
| BMI | 24.43(3.26) | 20.02–30.68 | 20.86(4.57) | 16.33–33.33 |
Fig 1Experimental protocol.
Total duration is 44–60 minutes due to variable recovery times.
Fig 2Participant preparation.
(a) ECG leads and Polar OH1 arm sensor placement on the participant. (b) The ECG leads connected to the g.Nautilus device. RA and LL are connected to two detachable electrodes, while LA is connected to the reference (REF) channel of the g.Nautilus. (c) The Polar OH1 sensor on the temple is secured by a sweatband. RA: Right arm electrode, LA: Left arm electrode, LL: Lower left chest electrode.
Fig 3Pipeline of deriving the criterion HR from ECG.
ECG denotes the HR derived at the i iteration.
Descriptive statistics of criterion measure and the three Polar sensor measurements.
| Minimum HR (bpm) | Maximum HR (bmp) | Mean ± SD (bpm) | |
|---|---|---|---|
| 54 | 178 | 112.15 ± 24.52 | |
| 52 | 180 | 112.42 ± 24.52 | |
| 53 | 180 | 112.47 ± 24.47 | |
| 52 | 181 | 112.43 ± 24.50 |
Fig 4Aggregate data analysis results.
Bland-Altman plots indicating mean bias scores and 95% limits of agreement (LoA) for the three sensor locations; (a) forearm (b) upper arm and (c) temple.
Results for the aggregated data at different Polar sensor locations (n = 25858), p < 0.0001*.
| Mean bias | 95% upper LoA | 95% lower LoA | ||
|---|---|---|---|---|
| 0.9946* | 0.27 ± 2.52 | 5.22 | -4.68 | |
| 0.9949* | 0.33 ± 2.46 | 5.15 | -4.49 | |
| 0.9947* | 0.28 ± 2.52 | 5.22 | -4.66 |
CI: confidence interval
Data for different HR ranges with respect to the mean HR derived from ECG.
| Data for | Data for | |||||
|---|---|---|---|---|---|---|
| Mean(SD) (bpm) | 94.01 | 94.10 | 94.02 | 133.08 | 133.09 | 133.08 |
| ICC | 0.9767 | 0.9776 | 0.9770 | 0.9924 | 0.9928 | 0.9921 |
| Mean bias (bpm) | 0.38 ± 2.94 | 0.47 ± 2.86 | 0.39 ± 2.91 | 0.15 ± 1.96 | 0.16 ± 1.91 | 0.15 ± 1.99 |
| 95% upper LoA (bpm) | 6.14 | 6.07 | 6.09 | 3.99 | 3.90 | 4.06 |
| 95% lower LoA (bpm) | -5.38 | -5.13 | -5.31 | -3.69 | -3.58 | -3.76 |
Descriptive statistics and the validation metrics for the entire protocol.
All data other than ICC given in bpm.
| Rest | Treadmill no inclination | Treadmill inclination | Cycle | Recovery | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 4 km/h | 5 km/h | 5.5 km/h | 4 km/h | 5 km/h | 5.5 km/h | 60 rpm | 80 rpm | ||||
| 2712 | 1439 | 1405 | 1311 | 1846 | 1944 | 2136 | 3192 | 3231 | 6642 | ||
| Forearm | Mean(SD) | 75.44 | 94.72 | 100.02 | 109.53 | 113.67 | 130.47 | 146.40 | 111.17 | 125.50 | 112.23 |
| Range (min–max) | 52–102 | 73–116 | 84–119 | 91–139 | 81–135 | 103–152 | 120–172 | 81–160 | 89–179 | 57–180 | |
| ICC | 0.9480 | 0.9687 | 0.9652 | 0.9853 | 0.9620 | 0.9816 | 0.9933 | 0.9898 | 0.9949 | 0.9920 | |
| ICC 95% CI upper bound | 0.9516 | 0.9718 | 0.9686 | 0.9874 | 0.9652 | 0.9838 | 0.9947 | 0.9905 | 0.9955 | 0.9927 | |
| ICC 95% CI lower bound | 0.9440 | 0.9654 | 0.9614 | 0.9828 | 0.9584 | 0.9789 | 0.9912 | 0.9890 | 0.9942 | 0.9913 | |
| Mean bias (SD) | -0.02 | -0.08 | -0.15 | 0.37 | -0.01 | 0.34 | 0.43 | 0.20 | 0.34 | 0.55 | |
| 95% upper LoA | 6.31 | 5.69 | 4.65 | 4.32 | 5.21 | 3.81 | 3.22 | 4.13 | 3.82 | 7.03 | |
| 95% lower LoA | -6.36 | -5.84 | -4.95 | -3.58 | -5.23 | -3.13 | -2.35 | -3.72 | -3.14 | -5.93 | |
| Upper arm | Mean(SD) | 75.71 | 94.85 | 100.18 | 109.58 | 113.81 | 130.44 | 146.39 | 111.14 | 125.55 | 112.21 |
| Range (min–max) | 53–108 | 72–115 | 84–119 | 91–139 | 80–136 | 104–152 | 120–172 | 81–160 | 95–179 | 57–180 | |
| ICC | 0.9493 | 0.9656 | 0.9682 | 0.9842 | 0.9637 | 0.9828 | 0.9932 | 0.9912 | 0.9951 | 0.9925 | |
| 95% CI upper bound | 0.9453 | 0.9619 | 0.9648 | 0.9812 | 0.9603 | 0.9805 | 0.9911 | 0.9905 | 0.9943 | 0.9918 | |
| 95% CI lower bound | 0.9529 | 0.9689 | 0.9713 | 0.9866 | 0.9668 | 0.9848 | 0.9946 | 0.9918 | 0.9957 | 0.9931 | |
| Mean bias (SD) | 0.25 | 0.05 | 0.01 | 0.42 | 0.13 | 0.31 | 0.43 | 0.18 | 0.39 | 0.53 | |
| 95% upper LoA | 6.43 | 6.57 | 4.57 | 4.52 | 5.22 | 3.65 | 3.25 | 3.82 | 3.77 | 6.82 | |
| 95% lower LoA | -5.93 | -6.46 | -4.54 | -3.68 | -4.97 | -3.04 | -2.38 | -3.46 | -2.30 | -5.76 | |
| Temple | Mean(SD) | 75.55 | 94.43 | 100.10 | 109.39 | 114.12 | 130.41 | 146.35 | 111.21 | 125.53 | 112.15 |
| Range (min–max) | 52–101 | 72–113 | 84–119 | 91–139 | 81–136 | 105–152 | 120–172 | 81–161 | 95–179 | 57–181 | |
| ICC | 0.9459 | 0.9611 | 0.9663 | 0.9860 | 0.9654 | 0.9821 | 0.9934 | 0.9906 | 0.9954 | 0.9919 | |
| 95% CI upper bound | 0.9418 | 0.9564 | 0.9627 | 0.9843 | 0.9609 | 0.9800 | 0.9917 | 0.9898 | 0.9946 | 0.9912 | |
| 95% CI lower bound | 0.9497 | 0.9653 | 0.9696 | 0.9875 | 0.9693 | 0.9840 | 0.9946 | 0.9914 | 0.9960 | 0.9924 | |
| Mean bias (SD) | 0.08 | -0.37 | -0.08 | 0.23 | 0.43 | 0.28 | 0.38 | 0.24 | 0.37 | 0.48 | |
| 95% upper LoA | 6.40 | 6.68 | 4.65 | 4.18 | 5.28 | 3.70 | 3.18 | 4.00 | 3.64 | 7.04 | |
| 95% lower LoA | -6.23 | -7.42 | -4.80 | -3.72 | -4.41 | -3.14 | -2.41 | -3.51 | -2.89 | -6.09 | |