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Literature DB >> 31017595

Chemical composition of DNA-encoded libraries, past present and future.

Abstract

DNA-encoded libraries represent an exciting and powerful modality for high-throughput screening. In this article, we highlight recent important advances in this field and also suggest some important directions that would make the technology even more powerful.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2019 PMID： 31017595 PMCID： PMC6520149 DOI： 10.1039/c9ob00581a

Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876

76 in total

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9. Versatile protein recognition by the encoded display of multiple chemical elements on a constant macrocyclic scaffold.

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Journal: Nat Chem Date: 2018-03-19 Impact factor: 24.427

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16 in total

1. A Solution Phase Platform to Characterize Chemical Reaction Compatibility with DNA-Encoded Chemical Library Synthesis.

Authors: Anokha S Ratnayake; Mark E Flanagan; Timothy L Foley; Justin D Smith; Jillian G Johnson; Justin Bellenger; Justin I Montgomery; Brian M Paegel
Journal: ACS Comb Sci Date: 2019-09-06 Impact factor: 3.784

Review 2. On-resin multicomponent protocols for biopolymer assembly and derivatization.

Authors: Daniel G Rivera; Manuel G Ricardo; Aldrin V Vasco; Ludger A Wessjohann; Erik V Van der Eycken
Journal: Nat Protoc Date: 2021-01-20 Impact factor: 13.491

Review 3. DNA-Encoded Chemical Libraries: A Comprehensive Review with Succesful Stories and Future Challenges.

Authors: Adrián Gironda-Martínez; Etienne J Donckele; Florent Samain; Dario Neri
Journal: ACS Pharmacol Transl Sci Date: 2021-06-14

Review 4. Strategies for developing DNA-encoded libraries beyond binding assays.

Authors: Yiran Huang; Yizhou Li; Xiaoyu Li
Journal: Nat Chem Date: 2022-02-04 Impact factor: 24.274

5. Multifunctional Building Blocks Compatible with Photoredox-Mediated Alkylation for DNA-Encoded Library Synthesis.

Authors: Shorouk O Badir; Jaehoon Sim; Katelyn Billings; Adam Csakai; Xuange Zhang; Weizhe Dong; Gary A Molander
Journal: Org Lett Date: 2020-01-15 Impact factor: 6.005

6. Solid-phase synthesis of DNA-encoded libraries via an "aldehyde explosion" strategy.

Authors: Nicholas G Paciaroni; John M Ndungu; Thomas Kodadek
Journal: Chem Commun (Camb) Date: 2020-03-26 Impact factor: 6.222

7. High-Throughput Quality Control Assay for the Solid-Phase Synthesis of DNA-Encoded Libraries of Macrocycles*.

Authors: Animesh Roy; Eric Koesema; Thomas Kodadek
Journal: Angew Chem Int Ed Engl Date: 2021-04-13 Impact factor: 15.336

8. Selection of DNA-encoded chemical libraries against endogenous membrane proteins on live cells.

Authors: Yiran Huang; Ling Meng; Qigui Nie; Yu Zhou; Langdong Chen; Shilian Yang; Yi Man Eva Fung; Xiaomeng Li; Cen Huang; Yan Cao; Yizhou Li; Xiaoyu Li
Journal: Nat Chem Date: 2020-12-21 Impact factor: 24.427

9. Homogeneous and Functional Group Tolerant Ring-Closing Metathesis for DNA-Encoded Chemical Libraries.

Authors: Olivier B C Monty; Pranavanand Nyshadham; Kurt M Bohren; Murugesan Palaniappan; Martin M Matzuk; Damian W Young; Nicholas Simmons
Journal: ACS Comb Sci Date: 2020-01-21 Impact factor: 3.784

10. Solution-Phase DNA-Compatible Pictet-Spengler Reaction Aided by Machine Learning Building Block Filtering.

Authors: Ke Li; Xiaohong Liu; Sixiu Liu; Yulong An; Yanfang Shen; Qingxia Sun; Xiaodong Shi; Wenji Su; Weiren Cui; Zhiqiang Duan; Letian Kuai; Hongfang Yang; Alexander L Satz; Kaixian Chen; Hualiang Jiang; Mingyue Zheng; Xuanjia Peng; Xiaojie Lu
Journal: iScience Date: 2020-05-07