Literature DB >> 30877608

Does Treatment of the Hiatus Influence the Outcomes of Magnetic Sphincter Augmentation for Chronic GERD?

Matías Mihura Irribarra1, Sandra Blitz2, Candice L Wilshire3, Anee Sophia Jackson3, Alexander S Farivar3, Ralph W Aye3, Christy M Dunst4, Brian E Louie5.   

Abstract

BACKGROUND: Hiatal dissection, restoration of esophageal intra-abdominal length, and crural closure are key components of successful antireflux surgery. The necessity of addressing these components prior to magnetic sphincter augmentation (MSA) has been questioned. We aimed to compare outcomes of MSA between groups with differing hiatal dissection and closure.
METHODS: We retrospectively reviewed 259 patients who underwent MSA from 2009 to 2017. Patients were categorized based on hiatal treatment: minimal dissection (MD), crural closure (CC), formal crural repair (FC), and extensive dissection without closure (ED). The primary outcome was normalization of postoperative DeMeester score (≤ 14.72). Univariable and multivariable logistic regression was used to assess which preoperative predictors achieved normalization.
RESULTS: Of the 197 patients, MD was used in 81 (41%); FC in 42 (22%); CC in 40 (20%); and ED in 34 (17%). Normalization occurred in 104 (53%) patients, with MD achieving normalization in 45/81 (56%); FC in 25/42 (60%); CC in 21/40 (53%); and ED 13/34 (38%). After regression, FC was most likely to normalize acid exposure. The presence of a hiatal hernia, defective LES, and higher preoperative DeMeester score were less likely to achieve normalization.
CONCLUSIONS: Hiatal dissection with restoration of esophageal length and crural closure during MSA increases the likelihood of normalizing acid exposure.

Entities:  

Keywords:  Antireflux surgery; Diaphragm; GERD; Hiatal hernia; Magnetic sphincter; Surgical outcomes

Year:  2019        PMID: 30877608     DOI: 10.1007/s11605-019-04180-6

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


  16 in total

1.  Multivariate analysis of factors predicting outcome after laparoscopic Nissen fundoplication.

Authors:  G M Campos; J H Peters; T R DeMeester; S Oberg; P F Crookes; S Tan; S R DeMeester; J A Hagen; C G Bremner
Journal:  J Gastrointest Surg       Date:  1999 May-Jun       Impact factor: 3.452

2.  Esophagogastric junction pressure topography after fundoplication.

Authors:  P J Kahrilas; S Lin; M Manka; G Shi; R J Joehl
Journal:  Surgery       Date:  2000-02       Impact factor: 3.982

3.  Hiatal hernia, lower esophageal sphincter incompetence, and effectiveness of Nissen fundoplication in the spectrum of gastroesophageal reflux disease.

Authors:  Reginald V N Lord; Steven R DeMeester; Jeffrey H Peters; Jeffrey A Hagen; Dino Elyssnia; Corinne T Sheth; Tom R DeMeester
Journal:  J Gastrointest Surg       Date:  2008-12-03       Impact factor: 3.452

4.  One hundred consecutive patients treated with magnetic sphincter augmentation for gastroesophageal reflux disease: 6 years of clinical experience from a single center.

Authors:  Luigi Bonavina; Greta Saino; Davide Bona; Andrea Sironi; Veronica Lazzari
Journal:  J Am Coll Surg       Date:  2013-07-12       Impact factor: 6.113

5.  The development of the GERD-HRQL symptom severity instrument.

Authors:  V Velanovich
Journal:  Dis Esophagus       Date:  2007       Impact factor: 3.429

6.  The value of high-resolution manometry in the assessment of the resting characteristics of the lower esophageal sphincter.

Authors:  Shahin Ayazi; Jeffrey A Hagen; Joerg Zehetner; Oliver Ross; Calvin Wu; Arzu Oezcelik; Emmanuele Abate; Helen J Sohn; Farzaneh Banki; John C Lipham; Steven R DeMeester; Tom R Demeester
Journal:  J Gastrointest Surg       Date:  2009-09-25       Impact factor: 3.452

7.  Esophageal sphincter device for gastroesophageal reflux disease.

Authors:  Robert A Ganz; Jeffrey H Peters; Santiago Horgan; Willem A Bemelman; Christy M Dunst; Steven A Edmundowicz; John C Lipham; James D Luketich; W Scott Melvin; Brant K Oelschlager; Steven C Schlack-Haerer; C Daniel Smith; Christopher C Smith; Dan Dunn; Paul A Taiganides
Journal:  N Engl J Med       Date:  2013-02-21       Impact factor: 91.245

8.  Manometric Changes to the Lower Esophageal Sphincter After Magnetic Sphincter Augmentation in Patients With Chronic Gastroesophageal Reflux Disease.

Authors:  Heather F Warren; Brian E Louie; Alexander S Farivar; Candice Wilshire; Ralph W Aye
Journal:  Ann Surg       Date:  2017-07       Impact factor: 12.969

9.  Magnetic augmentation of the lower esophageal sphincter: results of a feasibility clinical trial.

Authors:  Luigi Bonavina; Greta I Saino; Davide Bona; John Lipham; Robert A Ganz; Daniel Dunn; Tom DeMeester
Journal:  J Gastrointest Surg       Date:  2008-10-10       Impact factor: 3.452

10.  Length and pressure of the reconstructed lower esophageal sphincter is determined by both crural closure and Nissen fundoplication.

Authors:  Brian E Louie; Seema Kapur; Maurice Blitz; Alexander S Farivar; Eric Vallières; Ralph W Aye
Journal:  J Gastrointest Surg       Date:  2012-11-27       Impact factor: 3.452

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  2 in total

1.  Crural closure, not fundoplication, results in a significant decrease in lower esophageal sphincter distensibility.

Authors:  Mikhail Attaar; Bailey Su; Harry Wong; Zachary Callahan; Kristine Kuchta; Stephen Stearns; John G Linn; Woody Denham; Stephen P Haggerty; Michael B Ujiki
Journal:  Surg Endosc       Date:  2021-08-31       Impact factor: 3.453

2.  Six to 12-year outcomes of magnetic sphincter augmentation for gastroesophageal reflux disease.

Authors:  Davide Ferrari; Emanuele Asti; Veronica Lazzari; Stefano Siboni; Daniele Bernardi; Luigi Bonavina
Journal:  Sci Rep       Date:  2020-08-13       Impact factor: 4.379

  2 in total

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