Sachi Okuchi1, Yasutaka Fushimi2, Tomohisa Okada3, Akira Yamamoto1, Tsutomu Okada1, Takayuki Kikuchi4, Kazumichi Yoshida4, Susumu Miyamoto4, Kaori Togashi1. 1. Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. 2. Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. yfushimi@kuhp.kyoto-u.ac.jp. 3. Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan. 4. Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan.
Abstract
OBJECTIVES: To compare visualization of carotid plaques and vessel walls between 3D T1-fast spin echo imaging with conventional SPACE (T1-SPACE) and with a prototype compressed sensing T1-SPACE (CS-T1-SPACE) METHODS: This retrospective study was approved by the institutional review board. Participants comprised 43 patients (36 males, 7 females; mean age, 71 years) who underwent carotid MRI including T1-SPACE and CS-T1-SPACE. The quality of visualization for carotid plaques and vessel walls was evaluated using a 5-point scale, and signal intensity ratios (SRs) of the carotid plaques were measured and normalized to the adjacent sternomastoid muscle. Scores for the quality of visualization were compared between T1-SPACE and CS-T1-SPACE using the Wilcoxon signed-rank test. Statistical differences between SRs of plaques with T1-SPACE and CS-T1-SPACE were also evaluated using the Wilcoxon signed-rank test, and Spearman's correlation coefficient was calculated to investigate correlations. RESULTS: Visualization scores were significantly higher for CS-T1-SPACE than for T1-SPACE when evaluating carotid plaques (p = 0.0212) and vessel walls (p < 0.001). The SR of plaques did not differ significantly between T1-SPACE and CS-T1-SPACE (p = 0.5971). Spearman's correlation coefficient was significant (0.884; p < 0.0001). CONCLUSIONS: CS-T1-SPACE allowed better visualization scores and sharpness compared with T1-SPACE in evaluating carotid plaques and vessel walls, with a 2.5-fold accelerated scan time with comparable image quality. CS-T1-SPACE appears promising as a method for investigating carotid vessel walls, offering better image quality with a shorter acquisition time. KEY POINTS: • CS-T1-SPACE allowed better visualization compared with T1-SPACE in evaluating carotid plaques and vessel walls, with a 2.5-fold accelerated scan time with comparable image quality. • CS-T1-SPACE offers a promising method for investigating carotid vessel walls due to the better image quality with shorter acquisition time. • Physiological movements such as swallowing, arterial pulsations, and breathing induce motion artifacts in vessel wall imaging, and a shorter acquisition time can reduce artifacts from physiological movements.
OBJECTIVES: To compare visualization of carotid plaques and vessel walls between 3D T1-fast spin echo imaging with conventional SPACE (T1-SPACE) and with a prototype compressed sensing T1-SPACE (CS-T1-SPACE) METHODS: This retrospective study was approved by the institutional review board. Participants comprised 43 patients (36 males, 7 females; mean age, 71 years) who underwent carotid MRI including T1-SPACE and CS-T1-SPACE. The quality of visualization for carotid plaques and vessel walls was evaluated using a 5-point scale, and signal intensity ratios (SRs) of the carotid plaques were measured and normalized to the adjacent sternomastoid muscle. Scores for the quality of visualization were compared between T1-SPACE and CS-T1-SPACE using the Wilcoxon signed-rank test. Statistical differences between SRs of plaques with T1-SPACE and CS-T1-SPACE were also evaluated using the Wilcoxon signed-rank test, and Spearman's correlation coefficient was calculated to investigate correlations. RESULTS: Visualization scores were significantly higher for CS-T1-SPACE than for T1-SPACE when evaluating carotid plaques (p = 0.0212) and vessel walls (p < 0.001). The SR of plaques did not differ significantly between T1-SPACE and CS-T1-SPACE (p = 0.5971). Spearman's correlation coefficient was significant (0.884; p < 0.0001). CONCLUSIONS:CS-T1-SPACE allowed better visualization scores and sharpness compared with T1-SPACE in evaluating carotid plaques and vessel walls, with a 2.5-fold accelerated scan time with comparable image quality. CS-T1-SPACE appears promising as a method for investigating carotid vessel walls, offering better image quality with a shorter acquisition time. KEY POINTS: • CS-T1-SPACE allowed better visualization compared with T1-SPACE in evaluating carotid plaques and vessel walls, with a 2.5-fold accelerated scan time with comparable image quality. • CS-T1-SPACE offers a promising method for investigating carotid vessel walls due to the better image quality with shorter acquisition time. • Physiological movements such as swallowing, arterial pulsations, and breathing induce motion artifacts in vessel wall imaging, and a shorter acquisition time can reduce artifacts from physiological movements.
Entities:
Keywords:
Artifacts; Atherosclerosis; Carotid stenosis; Image reconstruction; Magnetic resonance imaging
Authors: Mark A Griswold; Peter M Jakob; Robin M Heidemann; Mathias Nittka; Vladimir Jellus; Jianmin Wang; Berthold Kiefer; Axel Haase Journal: Magn Reson Med Date: 2002-06 Impact factor: 4.668
Authors: R Boubertakh; C Prieto; P G Batchelor; S Uribe; D Atkinson; H Eggers; T S Sørensen; M S Hansen; R S Razavi; T Schaeffter Journal: Magn Reson Med Date: 2009-11 Impact factor: 4.668
Authors: Sarah E Vermeer; Tom Den Heijer; Peter J Koudstaal; Matthijs Oudkerk; Albert Hofman; Monique M B Breteler Journal: Stroke Date: 2003-02 Impact factor: 7.914
Authors: Jens Harald Kramer; Elisabeth Arnoldi; Christopher J François; Andrew L Wentland; Konstantin Nikolaou; Bernd J Wintersperger; Thomas M Grist Journal: Invest Radiol Date: 2013-03 Impact factor: 6.016
Authors: Loic Boussel; Gwenael Herigault; Alejandro de la Vega; Michel Nonent; Philippe Charles Douek; Jean Michel Serfaty Journal: J Magn Reson Imaging Date: 2006-03 Impact factor: 4.813