Literature DB >> 30488442

Technical Note: Time-gating to medical linear accelerator pulses: Stray radiation detector.

Muhammad Ramish Ashraf1, Petr Bruza1, Venkat Krishnaswamy1,2, David J Gladstone1,3,4, Brian W Pogue1,2.   

Abstract

PURPOSE: CCD cameras are employed to image scintillation and Cherenkov radiation in external beam radiotherapy. This is achieved by gating the camera to the linear accelerator (Linac) output. A direct output signal line from the linac is not always accessible and even in cases where such a signal is accessible, a physical wire connected to the output port can potentially alter Linac performance through electrical feedback. A scintillating detector for stray radiation inside the Linac room was developed to remotely time-gate to linac pulses for camera-based dosimetry.
METHODS: A scintillator coupled silicon photomultiplier detector was optimized and systematically tested for location sensitivity and for use with both x rays and electron beams, at different energies and field sizes. Cherenkov radiation emitted due to static photon beams was captured using the remote trigger and compared to the images captured using a wired trigger. The issue of false-positive event detection, due to additional neutron activated products with high energy beams, was addressed.
RESULTS: The designed circuit provided voltage >2.5 V even for distances up to 3 m from the isocenter with a 6 MV, 5 × 5 cm beam, using a Ø3 × 20 mm3 Bi4 Ge3 O12 (BGO) crystal. With a larger scintillator size, the detector could be placed even beyond 3 m distance. False-positive triggering was reduced by a coincidence detection scheme. Negligible fluctuations were observed in time-gated imaging of Cherenkov intensity emitted from a water phantom, when comparing directly connected vs this remote triggering approach.
CONCLUSION: The remote detector provides untethered synchronization to linac pulses. It is especially useful for remote Cherenkov imaging or remote scintillator dosimetry imaging during radiotherapeutic procedures when a direct line signal is not accessible.
© 2018 American Association of Physicists in Medicine.

Entities:  

Keywords:  cherenkov; linac; scintillation; time-gated acquistion

Mesh:

Year:  2018        PMID: 30488442      PMCID: PMC7122787          DOI: 10.1002/mp.13311

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  5 in total

1.  Cherenkov radiation fluence estimates in tissue for molecular imaging and therapy applications.

Authors:  Adam K Glaser; Rongxiao Zhang; Jacqueline M Andreozzi; David J Gladstone; Brian W Pogue
Journal:  Phys Med Biol       Date:  2015-08-13       Impact factor: 3.609

2.  Activation processes in a medical linear accelerator and spatial distribution of activation products.

Authors:  Helmut W Fischer; Ben E Tabot; Björn Poppe
Journal:  Phys Med Biol       Date:  2006-11-30       Impact factor: 3.609

3.  Secondary neutron spectra from modern Varian, Siemens, and Elekta linacs with multileaf collimators.

Authors:  Rebecca M Howell; Stephen F Kry; Eric Burgett; Nolan E Hertel; David S Followill
Journal:  Med Phys       Date:  2009-09       Impact factor: 4.071

4.  Time-gated Cherenkov emission spectroscopy from linear accelerator irradiation of tissue phantoms.

Authors:  Adam K Glaser; Rongxiao Zhang; Scott C Davis; David J Gladstone; Brian W Pogue
Journal:  Opt Lett       Date:  2012-04-01       Impact factor: 3.776

5.  Water-equivalent dosimeter array for small-field external beam radiotherapy.

Authors:  Louis Archambault; A Sam Beddar; Luc Gingras; Fréderic Lacroix; René Roy; Luc Beaulieu
Journal:  Med Phys       Date:  2007-05       Impact factor: 4.071

  5 in total
  5 in total

1.  Optical imaging provides rapid verification of static small beams, radiosurgery, and VMAT plans with millimeter resolution.

Authors:  Muhammad Ramish Ashraf; Petr Bruza; Brian W Pogue; Nathan Nelson; Benjamin B Williams; Lesley A Jarvis; David J Gladstone
Journal:  Med Phys       Date:  2019-10-04       Impact factor: 4.071

2.  Optical imaging method to quantify spatial dose variation due to the electron return effect in an MR-linac.

Authors:  Jacqueline M Andreozzi; Petr Brůža; Jochen Cammin; Brian W Pogue; David J Gladstone; Olga Green
Journal:  Med Phys       Date:  2019-12-25       Impact factor: 4.071

3.  Assessment of imaging Cherenkov and scintillation signals in head and neck radiotherapy.

Authors:  Daniel A Alexander; Irwin I Tendler; Petr Bruza; Xu Cao; Philip E Schaner; Bethany S Marshall; Lesley A Jarvis; David J Gladstone; Brian W Pogue
Journal:  Phys Med Biol       Date:  2019-07-18       Impact factor: 3.609

4.  Verification of field match lines in whole breast radiation therapy using Cherenkov imaging.

Authors:  Rachael Hachadorian; J Cedar Farwell; Petr Bruza; Michael Jermyn; David J Gladstone; Brian W Pogue; Lesley A Jarvis
Journal:  Radiother Oncol       Date:  2021-05-01       Impact factor: 6.901

5.  Technical Note: A novel dosimeter improves total skin electron therapy surface dosimetry workflow.

Authors:  Irwin I Tendler; Petr Bruza; Michael Jermyn; Jennifer Soter; Gregory Sharp; Benjamin Williams; Lesley A Jarvis; Brian Pogue; David J Gladstone
Journal:  J Appl Clin Med Phys       Date:  2020-04-19       Impact factor: 2.102

  5 in total

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