Literature DB >> 31472093

Optical imaging provides rapid verification of static small beams, radiosurgery, and VMAT plans with millimeter resolution.

Muhammad Ramish Ashraf1, Petr Bruza1, Brian W Pogue1,2, Nathan Nelson2, Benjamin B Williams1,2,3, Lesley A Jarvis2,3, David J Gladstone1,2,3.   

Abstract

PURPOSE: We demonstrate the feasibility of optical imaging as a quality assurance tool for static small beamlets, and pretreatment verification tool for radiosurgery and volumetric-modulated arc therapy (VMAT) plans.
METHODS: Small static beams and clinical VMAT plans were simulated in a treatment planning system (TPS) and delivered to a cylindrical tank filled with water-based liquid scintillator. Emission was imaged using a blue-sensitive, intensified CMOS camera time-gated to the linac pulses. For static beams, percentage depth and cross beam profiles of projected intensity distribution were compared to TPS data. Two-dimensional (2D) gamma analysis was performed on all clinical plans, and the technique was tested for sensitivity against common errors (multileaf collimator position, gantry angle) by inducing deliberate errors in the VMAT plans control points. The technique's detection limits for spatial resolution and the smallest number of control points that could be imaged reliably were also tested. The sensitivity to common delivery errors was also compared against a commercial 2.5D diode array dosimeter.
RESULTS: A spatial resolution of 1 mm was achieved with our imaging setup. The optical projected percentage depth intensity profiles agreed to within 2% relative to the TPS data for small static square beams (5, 10, and 50 mm2 ). For projected cross beam profiles, a gamma pass rate >99% was achieved for a 3%/1 mm criteria. All clinical plans passed the 3%/3 mm criteria with >95% passing rate. A static 5 mm beam with 20 Monitor Units could be measured with an average percent difference of 5.5 ± 3% relative to the TPS. The technique was sensitive to multileaf collimator errors down to 1 mm and gantry angle errors of 1°.
CONCLUSIONS: Optical imaging provides ample spatial resolution for imaging small beams. The ability to faithfully image down to 20 MU of 5 mm, 6 MV beamlets prove the ability to perform quality assurance for each control point within dynamic plans. The technique is sensitive to small offset errors in gantry angles and multileaf collimator (MLC) leaf positions, and at certain scenario, it exhibits higher sensitivity than a commercial 2.5D diode array.
© 2019 American Association of Physicists in Medicine.

Entities:  

Keywords:  SBRT; SRS; optical imaging; scintillation; small fields

Mesh:

Year:  2019        PMID: 31472093      PMCID: PMC7082501          DOI: 10.1002/mp.13797

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  25 in total

Review 1.  Volumetric modulated arc therapy: a review of current literature and clinical use in practice.

Authors:  M Teoh; C H Clark; K Wood; S Whitaker; A Nisbet
Journal:  Br J Radiol       Date:  2011-11       Impact factor: 3.039

2.  Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial.

Authors:  Hidefumi Aoyama; Hiroki Shirato; Masao Tago; Keiichi Nakagawa; Tatsuya Toyoda; Kazuo Hatano; Masahiro Kenjyo; Natsuo Oya; Saeko Hirota; Hiroki Shioura; Etsuo Kunieda; Taisuke Inomata; Kazushige Hayakawa; Norio Katoh; Gen Kobashi
Journal:  JAMA       Date:  2006-06-07       Impact factor: 56.272

3.  Measurement of output factors for small photon beams.

Authors:  Otto A Sauer; Jürgen Wilbert
Journal:  Med Phys       Date:  2007-06       Impact factor: 4.071

4.  Volumetric modulated arc therapy: IMRT in a single gantry arc.

Authors:  Karl Otto
Journal:  Med Phys       Date:  2008-01       Impact factor: 4.071

Review 5.  A literature review of electronic portal imaging for radiotherapy dosimetry.

Authors:  Wouter van Elmpt; Leah McDermott; Sebastiaan Nijsten; Markus Wendling; Philippe Lambin; Ben Mijnheer
Journal:  Radiother Oncol       Date:  2008-08-14       Impact factor: 6.280

6.  A technique for the quantitative evaluation of dose distributions.

Authors:  D A Low; W B Harms; S Mutic; J A Purdy
Journal:  Med Phys       Date:  1998-05       Impact factor: 4.071

7.  Gamma index comparison of three VMAT QA systems and evaluation of their sensitivity to delivery errors.

Authors:  Laure Vieillevigne; Jeremy Molinier; Thomas Brun; Regis Ferrand
Journal:  Phys Med       Date:  2015-06-19       Impact factor: 2.685

8.  Absorbed dose perturbation caused by diodes for small field photon dosimetry.

Authors:  A S Beddar; D J Mason; P F O'Brien
Journal:  Med Phys       Date:  1994-07       Impact factor: 4.071

9.  Ionization chamber volume averaging effects in dynamic intensity modulated radiation therapy beams.

Authors:  Daniel A Low; Parag Parikh; James F Dempsey; Sasha Wahab; Saiful Huq
Journal:  Med Phys       Date:  2003-07       Impact factor: 4.071

10.  Stereotactic body radiotherapy for centrally located early-stage non-small cell lung cancer or lung metastases from the RSSearch(®) patient registry.

Authors:  Joanne N Davis; Clinton Medbery; Sanjeev Sharma; John Pablo; Frank Kimsey; David Perry; Alexander Muacevic; Anand Mahadevan
Journal:  Radiat Oncol       Date:  2015-05-15       Impact factor: 3.481

View more
  2 in total

Review 1.  Ultra-high dose rate electron beams and the FLASH effect: From preclinical evidence to a new radiotherapy paradigm.

Authors:  Emil Schüler; Munjal Acharya; Pierre Montay-Gruel; Billy W Loo; Marie-Catherine Vozenin; Peter G Maxim
Journal:  Med Phys       Date:  2022-01-19       Impact factor: 4.506

2.  Visual Isocenter Position Enhanced Review (VIPER): a Cherenkov imaging-based solution for MR-linac daily QA.

Authors:  Daniel A Alexander; Petr Bruza; Aris G Rassias; Jacqueline M Andreozzi; Brian W Pogue; Rongxiao Zhang; David J Gladstone
Journal:  Med Phys       Date:  2021-05-09       Impact factor: 4.506

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.