Literature DB >> 3027417

env-encoded residues are not required for transformation by p48v-myb.

J S Lipsick, C E Ibanez.   

Abstract

The v-myb oncogene of avian myeloblastosis virus induces acute myeloblastic leukemia in chickens and transforms avian myeloid cells in vitro. The protein product of this oncogene, p48v-myb, is partially encoded by the retroviral gag and env genes. We demonstrated that the env-encoded carboxyl terminus of p48v-myb is not required for transformation. Our results showed, in addition, that a coding region of c-myb which is not essential for transformation was transduced by avian myeloblastosis virus.

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Year:  1987        PMID： 3027417      PMCID： PMC254042          DOI： 10.1128/JVI.61.3.933-936.1987

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  25 in total

1.  Morphological conversion of cell cultures by avian myeloblastosis virus.

Authors:  M A BALUDA; I E GOETZ
Journal:  Virology       Date:  1961-10       Impact factor: 3.616

2.  Chicken hematopoietic cells transformed by seven strains of defective avian leukemia viruses display three distinct phenotypes of differentiation.

Authors:  H Beug; A von Kirchbach; G Döderlein; J F Conscience; T Graf
Journal:  Cell       Date:  1979-10       Impact factor: 41.582

3.  Three new types of viral oncogene of cellular origin specific for haematopoietic cell transformation.

Authors:  M Roussel; S Saule; C Lagrou; C Rommens; H Beug; T Graf; D Stehelin
Journal:  Nature       Date:  1979-10-11       Impact factor: 49.962

4.  Focus assay and defectiveness of avian myeloblastosis virus.

Authors:  C Moscovici; L Gazzolo; M G Moscovici
Journal:  Virology       Date:  1975-11       Impact factor: 3.616

5.  Replicating, differentiated macrophages can serve as in vitro targets for transformation by avian myeloblastosis virus.

Authors:  E M Durban; D Boettiger
Journal:  J Virol       Date:  1981-01       Impact factor: 5.103

6.  Cellular sequences are present in the presumptive avian myeloblastosis virus genome.

Authors:  L M Souza; J N Strommer; R L Hillyard; M C Komaromy; M A Baluda
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

7.  Size and genetic content of virus-specific RNA in myeloblasts transformed by avian myeloblastosis virus (AMV).

Authors:  J H Chen; W S Hayward; C Moscovici
Journal:  Virology       Date:  1981-04-15       Impact factor: 3.616

8.  Nucleotide sequence of the transforming gene of avian myeloblastosis virus.

Authors:  K E Rushlow; J A Lautenberger; T S Papas; M A Baluda; B Perbal; J G Chirikjian; E P Reddy
Journal:  Science       Date:  1982-06-25       Impact factor: 47.728

9.  Genetic structure of avian myeloblastosis virus, released from transformed myeloblasts as a defective virus particle.

Authors:  P H Duesberg; K Bister; C Moscovici
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

10.  The genome and the intracellular RNAs of avian myeloblastosis virus.

Authors:  T J Gonda; D K Sheiness; L Fanshier; J M Bishop; C Moscovici; M G Moscovici
Journal:  Cell       Date:  1981-01       Impact factor: 41.582
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  12 in total

1.  Protein truncation is required for the activation of the c-myb proto-oncogene.

Authors:  F A Grässer; T Graf; J S Lipsick
Journal:  Mol Cell Biol       Date:  1991-08       Impact factor: 4.272

2.  Transformation by v-myb correlates with trans-activation of gene expression.

Authors:  T Lane; C Ibanez; A Garcia; T Graf; J Lipsick
Journal:  Mol Cell Biol       Date:  1990-06       Impact factor: 4.272

3.  v-myb does not prevent the expression of c-myb in avian erythroblasts.

Authors:  J S Lipsick
Journal:  J Virol       Date:  1987-10       Impact factor: 5.103

4.  DNA-binding activity associated with the v-myb oncogene product is not sufficient for transformation.

Authors:  C E Ibanez; A Garcia; U Stober-Grässer; J S Lipsick
Journal:  J Virol       Date:  1988-11       Impact factor: 5.103

5.  Specific amino acid substitutions are not required for transformation by v-myb of avian myeloblastosis virus.

Authors:  U Stober-Grässer; J S Lipsick
Journal:  J Virol       Date:  1988-03       Impact factor: 5.103

6.  Structural and functional domains of the myb oncogene: requirements for nuclear transport, myeloid transformation, and colony formation.

Authors:  C E Ibanez; J S Lipsick
Journal:  J Virol       Date:  1988-06       Impact factor: 5.103

7.  Mutations in the DNA-binding and transcriptional activation domains of v-Myb cooperate in transformation.

Authors:  P W Dini; J T Eltman; J S Lipsick
Journal:  J Virol       Date:  1995-04       Impact factor: 5.103

8.  Functional analysis of carboxy-terminal deletion mutants of c-Myb.

Authors:  D M Wang; J W Dubendorff; C H Woo; J S Lipsick
Journal:  J Virol       Date:  1999-07       Impact factor: 5.103

9.  Individual repeats of Drosophila Myb can function in transformation by v-Myb.

Authors:  X Bin; J S Lipsick
Journal:  J Virol       Date:  1993-12       Impact factor: 5.103

10.  The carboxyterminus of human c-myb protein stimulates activated transcription in trans.

Authors:  G Vorbrueggen; F Kalkbrenner; S Guehmann; K Moelling
Journal:  Nucleic Acids Res       Date:  1994-07-11       Impact factor: 16.971
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