| Literature DB >> 226888 |
M Roussel, S Saule, C Lagrou, C Rommens, H Beug, T Graf, D Stehelin.
Abstract
The RNAs of seven replication-defective leukaemia virus (DLV) strains contain three types of unique sequences, which correlate with the capacity of a given virus strain to transform erythroblasts, macrophage-like cells and myeloblasts, respectively. These sequences, termed erb, mac and myb, have their counterparts in the normal DNA of avian and mammalian species. Our results indicate that DLVs represent recombinants between a common 'vector' related to a chicken endogenous virus and one of three types of cellular gene possibly involved in haematopoietic differentiation.Entities:
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Year: 1979 PMID： 226888 DOI： 10.1038/281452a0
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962