Literature DB >> 6283631

Nucleotide sequence of the transforming gene of avian myeloblastosis virus.

K E Rushlow, J A Lautenberger, T S Papas, M A Baluda, B Perbal, J G Chirikjian, E P Reddy.   

Abstract

Avian myeloblastosis virus is defective in reproductive capacity, requiring a helper virus to provide the viral proteins essential for synthesis of new infectious virus. This virus arose by recombination of the nondefective helper virus and host cellular sequences present within the normal avian genome. These latter sequences are essential for leukemogenic activity. The complete nucleotide sequence of this region is reported. Within the acquired cellular sequences there is an open reading frame of 795 nucleotides starting with the initiation codon ATG (adenine, thymine, guanine) and terminating with the triplet TAG. This open reading frame could code for the putative transforming protein of 265 amino acids with a molecular weight of approximately 30,000.

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Year:  1982        PMID： 6283631     DOI： 10.1126/science.6283631

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  54 in total

1.  Definition of functional domains in P135gag-myb-ets and p48v-myb proteins required to maintain the response of neuroretina cells to basic fibroblast growth factor.

Authors:  C Garrido; D Leprince; J S Lipsick; D Stehelin; D Gospodarowicz; S Saule
Journal:  J Virol       Date:  1992-01       Impact factor: 5.103

2.  Myb and Ets proteins cooperate in transcriptional activation of the mim-1 promoter.

Authors:  H Dudek; R V Tantravahi; V N Rao; E S Reddy; E P Reddy
Journal:  Proc Natl Acad Sci U S A       Date:  1992-02-15       Impact factor: 11.205

3.  Transformation by v-myb correlates with trans-activation of gene expression.

Authors:  T Lane; C Ibanez; A Garcia; T Graf; J Lipsick
Journal:  Mol Cell Biol       Date:  1990-06       Impact factor: 4.272

4.  Transcriptional trans-repression by the c-myb proto-oncogene product.

Authors:  H Nakagoshi; T Nagase; Y Ueno; S Ishii
Journal:  Nucleic Acids Res       Date:  1989-09-25       Impact factor: 16.971

5.  Aberrant splicing events that are induced by proviral integration: implications for myb oncogene activation.

Authors:  D Rosson; D Dugan; E P Reddy
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

6.  v-myb does not prevent the expression of c-myb in avian erythroblasts.

Authors:  J S Lipsick
Journal:  J Virol       Date:  1987-10       Impact factor: 5.103

7.  v-myb blocks granulocyte colony-stimulating factor-induced myeloid cell differentiation but not proliferation.

Authors:  G Patel; B Kreider; G Rovera; E P Reddy
Journal:  Mol Cell Biol       Date:  1993-04       Impact factor: 4.272

8.  Structural organization and expression of human DNA sequences related to the transforming gene of avian myeloblastosis virus.

Authors:  G Franchini; F Wong-Staal; M A Baluda; C Lengel; S R Tronick
Journal:  Proc Natl Acad Sci U S A       Date:  1983-12       Impact factor: 11.205

9.  Cellular myc (c-myc) in fish (rainbow trout): its relationship to other vertebrate myc genes and to the transforming genes of the MC29 family of viruses.

Authors:  R J Van Beneden; D K Watson; T T Chen; J A Lautenberger; T S Papas
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

10.  Avian myeloblastosis virus and E26 virus oncogene products are nuclear proteins.

Authors:  W J Boyle; M A Lampert; J S Lipsick; M A Baluda
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205
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