Literature DB >> 3023956

Human c-ros-1 gene homologous to the v-ros sequence of UR2 sarcoma virus encodes for a transmembrane receptorlike molecule.

H Matsushime, L H Wang, M Shibuya.   

Abstract

We isolated a human gene (designated c-ros-1) homologous to the v-ros sequence of UR2 sarcoma virus. Ten exons, 1,414 base pairs spanning 26 kilobases, contained a tyrosine kinase domain, a transmembrane domain, and a part of an extracellular domain carrying an N glycosylation site which was not acquired by UR2 sarcoma virus. The predicted structure of c-ros-1 is unique among the src family and clearly distinct from the human insulin receptor.

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Year:  1986        PMID： 3023956      PMCID： PMC367872          DOI： 10.1128/mcb.6.8.3000-3004.1986

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  18 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Avian sarcoma virus UR2 encodes a transforming protein which is associated with a unique protein kinase activity.

Authors:  R A Feldman; L H Wang; H Hanafusa; P C Balduzzi
Journal:  J Virol       Date:  1982-04       Impact factor: 5.103

3.  Proto-oncogene c-ros codes for a molecule with structural features common to those of growth factor receptors and displays tissue specific and developmentally regulated expression.

Authors:  W S Neckameyer; M Shibuya; M T Hsu; L H Wang
Journal:  Mol Cell Biol       Date:  1986-05       Impact factor: 4.272

4.  Isolation and structural mapping of a human c-src gene homologous to the transforming gene (v-src) of Rous sarcoma virus.

Authors:  C P Gibbs; A Tanaka; S K Anderson; J Radul; J Baar; A Ridgway; H J Kung; D J Fujita
Journal:  J Virol       Date:  1985-01       Impact factor: 5.103

5.  Nucleotide sequence of avian sarcoma virus UR2 and comparison of its transforming gene with other members of the tyrosine protein kinase oncogene family.

Authors:  W S Neckameyer; L H Wang
Journal:  J Virol       Date:  1985-03       Impact factor: 5.103

6.  Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences.

Authors:  J Downward; Y Yarden; E Mayes; G Scrace; N Totty; P Stockwell; A Ullrich; J Schlessinger; M D Waterfield
Journal:  Nature       Date:  1984 Feb 9-15       Impact factor: 49.962

7.  Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells.

Authors:  A Ullrich; L Coussens; J S Hayflick; T J Dull; A Gray; A W Tam; J Lee; Y Yarden; T A Libermann; J Schlessinger
Journal:  Nature       Date:  1984 May 31-Jun 6       Impact factor: 49.962

8.  Cellular sequences related to three new onc genes of avian sarcoma virus (fps, yes, and ros) and their expression in normal and transformed cells.

Authors:  M Shibuya; H Hanafusa; P C Balduzzi
Journal:  J Virol       Date:  1982-04       Impact factor: 5.103

9.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

10.  Some biological properties of two new avian sarcoma viruses.

Authors:  P C Balduzzi; M F Notter; H R Morgan; M Shibuya
Journal:  J Virol       Date:  1981-10       Impact factor: 5.103
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  42 in total

1.  Oncogenic targeting of an activated tyrosine kinase to the Golgi apparatus in a glioblastoma.

Authors:  Alan Charest; Vicky Kheifets; Julie Park; Keara Lane; Kevin McMahon; Cathy L Nutt; David Housman
Journal:  Proc Natl Acad Sci U S A       Date:  2003-01-21       Impact factor: 11.205

2.  Expression and rearrangement of the ROS1 gene in human glioblastoma cells.

Authors:  C Birchmeier; S Sharma; M Wigler
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

3.  Amino acids bracketing the predicted transmembrane domains of membrane proteins.

Authors:  C Pidgeon; R L Williard; S C Schroeder
Journal:  Pharm Res       Date:  1989-09       Impact factor: 4.200

4.  Two point mutations in the transmembrane domain of P68gag-ros inactive its transforming activity and cause a delay in membrane association.

Authors:  S M Jong; L H Wang
Journal:  J Virol       Date:  1991-01       Impact factor: 5.103

5.  Crizotinib in ROS1-rearranged non-small-cell lung cancer.

Authors:  Alice T Shaw; Sai-Hong I Ou; Yung-Jue Bang; D Ross Camidge; Benjamin J Solomon; Ravi Salgia; Gregory J Riely; Marileila Varella-Garcia; Geoffrey I Shapiro; Daniel B Costa; Robert C Doebele; Long Phi Le; Zongli Zheng; Weiwei Tan; Patricia Stephenson; S Martin Shreeve; Lesley M Tye; James G Christensen; Keith D Wilner; Jeffrey W Clark; A John Iafrate
Journal:  N Engl J Med       Date:  2014-09-27       Impact factor: 91.245

Review 6.  The insulin receptor: signalling mechanism and contribution to the pathogenesis of insulin resistance.

Authors:  H U Häring
Journal:  Diabetologia       Date:  1991-12       Impact factor: 10.122

7.  Characterization of ROS1 cDNA from a human glioblastoma cell line.

Authors:  C Birchmeier; K O'Neill; M Riggs; M Wigler
Journal:  Proc Natl Acad Sci U S A       Date:  1990-06       Impact factor: 11.205

8.  Structure of the human insulin receptor gene and characterization of its promoter.

Authors:  S Seino; M Seino; S Nishi; G I Bell
Journal:  Proc Natl Acad Sci U S A       Date:  1989-01       Impact factor: 11.205

9.  Activation of Neu (ErbB-2) mediated by disulfide bond-induced dimerization reveals a receptor tyrosine kinase dimer interface.

Authors:  C L Burke; D F Stern
Journal:  Mol Cell Biol       Date:  1998-09       Impact factor: 4.272

Review 10.  Molecular pathways: ROS1 fusion proteins in cancer.

Authors:  Kurtis D Davies; Robert C Doebele
Journal:  Clin Cancer Res       Date:  2013-05-29       Impact factor: 12.531
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