Literature DB >> 2352949

Characterization of ROS1 cDNA from a human glioblastoma cell line.

C Birchmeier1, K O'Neill, M Riggs, M Wigler.   

Abstract

We have isolated and characterized a human ROS1 cDNA from the glioblastoma cell line SW-1088. The cDNA, 8.3 kilobases long, has the potential to encode a transmembrane tyrosine-specific protein kinase with a predicted molecular mass of 259 kDa. The putative extracellular domain of ROS1 is homologous to the extracellular domain of the sevenless gene product from Drosophila. No comparable similarities in the extracellular domains were found between ROS1 and other receptor-type tyrosine kinases. Together, ROS1 and sevenless gene products define a distinct subclass of transmembrane tyrosine kinases.

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Year:  1990        PMID： 2352949      PMCID： PMC54205          DOI： 10.1073/pnas.87.12.4799

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  27 in total

1.  Characterization of the ros1-gene products expressed in human glioblastoma cell lines.

Authors:  S Sharma; C Birchmeier; J Nikawa; K O'Neill; L Rodgers; M Wigler
Journal:  Oncogene Res       Date:  1989

2.  The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1.

Authors:  C J Sherr; C W Rettenmier; R Sacca; M F Roussel; A T Look; E R Stanley
Journal:  Cell       Date:  1985-07       Impact factor: 41.582

3.  New human transforming genes detected by a tumorigenicity assay.

Authors:  O Fasano; D Birnbaum; L Edlund; J Fogh; M Wigler
Journal:  Mol Cell Biol       Date:  1984-09       Impact factor: 4.272

Review 4.  Compilation of published signal sequences.

Authors:  M E Watson
Journal:  Nucleic Acids Res       Date:  1984-07-11       Impact factor: 16.971

5.  A comprehensive set of sequence analysis programs for the VAX.

Authors:  J Devereux; P Haeberli; O Smithies
Journal:  Nucleic Acids Res       Date:  1984-01-11       Impact factor: 16.971

6.  The erbB gene of avian erythroblastosis virus is a member of the src gene family.

Authors:  T Yamamoto; T Nishida; N Miyajima; S Kawai; T Ooi; K Toyoshima
Journal:  Cell       Date:  1983-11       Impact factor: 41.582

7.  Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs.

Authors:  M Kozak
Journal:  Nucleic Acids Res       Date:  1984-01-25       Impact factor: 16.971

8.  Nucleotide sequence of the feline retroviral oncogene v-fms shows unexpected homology with oncogenes encoding tyrosine-specific protein kinases.

Authors:  A Hampe; M Gobet; C J Sherr; F Galibert
Journal:  Proc Natl Acad Sci U S A       Date:  1984-01       Impact factor: 11.205

9.  Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells.

Authors:  A Ullrich; L Coussens; J S Hayflick; T J Dull; A Gray; A W Tam; J Lee; Y Yarden; T A Libermann; J Schlessinger
Journal:  Nature       Date:  1984 May 31-Jun 6       Impact factor: 49.962

10.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205
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  35 in total

1.  Comparison of the sevenless genes of Drosophila virilis and Drosophila melanogaster.

Authors:  W M Michael; D D Bowtell; G M Rubin
Journal:  Proc Natl Acad Sci U S A       Date:  1990-07       Impact factor: 11.205

Review 2.  An analysis of vertebrate mRNA sequences: intimations of translational control.

Authors:  M Kozak
Journal:  J Cell Biol       Date:  1991-11       Impact factor: 10.539

3.  Two chimeric receptors of epidermal growth factor receptor and c-Ros that differ in their transmembrane domains have opposite effects on cell growth.

Authors:  Q Xiong; J L Chan; C S Zong; L H Wang
Journal:  Mol Cell Biol       Date:  1996-04       Impact factor: 4.272

Review 4.  Lung cancer as a paradigm for precision oncology in solid tumours.

Authors:  Simon Schallenberg; Sabine Merkelbach-Bruse; Reinhard Buettner
Journal:  Virchows Arch       Date:  2017-07-20       Impact factor: 4.064

5.  Cancer genes in lung cancer: racial disparities: are there any?

Authors:  Ahmed El-Telbany; Patrick C Ma
Journal:  Genes Cancer       Date:  2012-07

6.  ROS1 rearrangements define a unique molecular class of lung cancers.

Authors:  Kristin Bergethon; Alice T Shaw; Sai-Hong Ignatius Ou; Ryohei Katayama; Christine M Lovly; Nerina T McDonald; Pierre P Massion; Christina Siwak-Tapp; Adriana Gonzalez; Rong Fang; Eugene J Mark; Julie M Batten; Haiquan Chen; Keith D Wilner; Eunice L Kwak; Jeffrey W Clark; David P Carbone; Hongbin Ji; Jeffrey A Engelman; Mari Mino-Kenudson; William Pao; A John Iafrate
Journal:  J Clin Oncol       Date:  2012-01-03       Impact factor: 44.544

Review 7.  Personalizing therapy in advanced non-small cell lung cancer.

Authors:  Liza C Villaruz; Timothy F Burns; Vasilis S Ramfidis; Mark A Socinski
Journal:  Semin Respir Crit Care Med       Date:  2013-11-20       Impact factor: 3.119

8.  PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutations.

Authors:  Helen Y Zou; Qiuhua Li; Lars D Engstrom; Melissa West; Vicky Appleman; Katy A Wong; Michele McTigue; Ya-Li Deng; Wei Liu; Alexei Brooun; Sergei Timofeevski; Scott R P McDonnell; Ping Jiang; Matthew D Falk; Patrick B Lappin; Timothy Affolter; Tim Nichols; Wenyue Hu; Justine Lam; Ted W Johnson; Tod Smeal; Al Charest; Valeria R Fantin
Journal:  Proc Natl Acad Sci U S A       Date:  2015-03-02       Impact factor: 11.205

9.  axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.

Authors:  J P O'Bryan; R A Frye; P C Cogswell; A Neubauer; B Kitch; C Prokop; R Espinosa; M M Le Beau; H S Earp; E T Liu
Journal:  Mol Cell Biol       Date:  1991-10       Impact factor: 4.272

10.  Molecular and biochemical bases for activation of the transforming potential of the proto-oncogene c-ros.

Authors:  C S Zong; B Poon; J Chen; L H Wang
Journal:  J Virol       Date:  1993-11       Impact factor: 5.103
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