Literature DB >> 3018513

DNA-mediated transfer and expression of a human DNA repair gene that demethylates O6-methylguanine.

R Ding, K Ghosh, A Eastman, E Bresnick.   

Abstract

Human liver DNA was transfected into CHO cells (mex-) along with pSV2gpt and colonies were selected first for resistance to mycophenolic acid and then to chloroethylnitrosourea. Transformants were obtained that contained approximately 10,000 molecules of O6-alkylguanine alkyltransferase (mex+) per cell. Their genome contained at least three copies of the human Alu sequence.

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Year:  1985        PMID： 3018513      PMCID： PMC369147          DOI： 10.1128/mcb.5.11.3293-3296.1985

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  22 in total

1.  Transformation of mammalian cells with genes from procaryotes and eucaryotes.

Authors:  M Wigler; R Sweet; G K Sim; B Wold; A Pellicer; E Lacy; T Maniatis; S Silverstein; R Axel
Journal:  Cell       Date:  1979-04       Impact factor: 41.582

2.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

3.  DNA cross-linking and monoadduct repair in nitrosourea-treated human tumour cells.

Authors:  L C Erickson; G Laurent; N A Sharkey; K W Kohn
Journal:  Nature       Date:  1980-12-25       Impact factor: 49.962

4.  A system in mouse liver for the repair of O6-methylguanine lesions in methylated DNA.

Authors:  J M Bogden; A Eastman; E Bresnick
Journal:  Nucleic Acids Res       Date:  1981-07-10       Impact factor: 16.971

5.  DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

Authors:  M Wigler; A Pellicer; S Silverstein; R Axel; G Urlaub; L Chasin
Journal:  Proc Natl Acad Sci U S A       Date:  1979-03       Impact factor: 11.205

6.  Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue.

Authors:  M Olsson; T Lindahl
Journal:  J Biol Chem       Date:  1980-11-25       Impact factor: 5.157

7.  Evidence for an adaptive DNA repair pathway in CHO and human skin fibroblast cell lines.

Authors:  L Samson; J L Schwartz
Journal:  Nature       Date:  1980-10-30       Impact factor: 49.962

8.  Inability of Chinese hamster ovary cells to excise O6-alkylguanine.

Authors:  R Goth-Goldstein
Journal:  Cancer Res       Date:  1980-07       Impact factor: 12.701

9.  Repair of O6-ethylguanine in DNA by a chromatin fraction from rat liver: transfer of the ethyl group to an acceptor protein.

Authors:  J R Mehta; D B Ludlum; A Renard; W G Verly
Journal:  Proc Natl Acad Sci U S A       Date:  1981-11       Impact factor: 11.205

10.  Removal of O6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines.

Authors:  R Sklar; B Strauss
Journal:  Nature       Date:  1981-01-29       Impact factor: 49.962
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  10 in total

1.  Site-specific mutagenesis by O6-alkylguanines located in the chromosomes of mammalian cells: influence of the mammalian O6-alkylguanine-DNA alkyltransferase.

Authors:  K S Ellison; E Dogliotti; T D Connors; A K Basu; J M Essigmann
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

Review 2.  Self-destruction and tolerance in resistance of mammalian cells to alkylation damage.

Authors:  P Karran; M Bignami
Journal:  Nucleic Acids Res       Date:  1992-06-25       Impact factor: 16.971

3.  Transfer of human genes conferring resistance to methylating mutagens, but not to UV irradiation and cross-linking agents, into Chinese hamster ovary cells.

Authors:  B Kaina; A A Van Zeeland; C Backendorf; H W Thielmann; P Van de Putte
Journal:  Mol Cell Biol       Date:  1987-05       Impact factor: 4.272

4.  Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine.

Authors:  K Tano; S Shiota; J Collier; R S Foote; S Mitra
Journal:  Proc Natl Acad Sci U S A       Date:  1990-01       Impact factor: 11.205

Review 5.  Identification of human genes involved in repair and tolerance of DNA damage.

Authors:  B Kaina; G Fritz; T Coquerelle
Journal:  Radiat Environ Biophys       Date:  1991       Impact factor: 1.925

6.  Ataxia telangiectasia resists gene cloning: an account of parameters determining gene transfer into human recipient cells.

Authors:  H Lohrer; M Blum; P Herrlich
Journal:  Mol Gen Genet       Date:  1988-06

7.  Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents.

Authors:  M E Dolan; R C Moschel; A E Pegg
Journal:  Proc Natl Acad Sci U S A       Date:  1990-07       Impact factor: 11.205

8.  Repair-deficient xeroderma pigmentosum cells made UV light resistant by fusion with X-ray-inactivated Chinese hamster cells.

Authors:  D Karentz; J E Cleaver
Journal:  Mol Cell Biol       Date:  1986-10       Impact factor: 4.272

9.  Suppression of human DNA alkylation-repair defects by Escherichia coli DNA-repair genes.

Authors:  L Samson; B Derfler; E A Waldstein
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

10.  In vivo depletion of O6-alkylguanine-DNA-alkyltransferase in lymphocytes and melanoma of patients treated with CB 10-277, a new DTIC analogue.

Authors:  S M Lee; N Thatcher; D Crowther; G P Margison
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333
  10 in total

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