Literature DB >> 2000442

Identification of human genes involved in repair and tolerance of DNA damage.

B Kaina1, G Fritz, T Coquerelle.   

Abstract

An overview is presented on strategies of cloning mammalian DNA repair genes. Complementation of human and rodent repair defects and mutagen hypersensitivities by chromosome and DNA mediated gene transfer and mRNA microinjection is described, and the features of the cloned human DNA repair genes are summarized. It is shown that transfection of repair deficient cell lines with cloned bacterial and human genes may give rise to protection from the genotoxic effects of mutagens.

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Year:  1991        PMID： 2000442     DOI： 10.1007/bf01595570

Source DB:  PubMed          Journal:  Radiat Environ Biophys        ISSN： 0301-634X            Impact factor:   1.925


  79 in total

1.  Human tumor cell strains defective in the repair of alkylation damage.

Authors:  R S Day; C H Ziolkowski; D A Scudiero; S A Meyer; M R Mattern
Journal:  Carcinogenesis       Date:  1980-01       Impact factor: 4.944

2.  Expression and cloning of complementary DNA for a human enzyme that repairs O6-methylguanine in DNA.

Authors:  H Hayakawa; G Koike; M Sekiguchi
Journal:  J Mol Biol       Date:  1990-06-20       Impact factor: 5.469

3.  Cyclobutane-pyrimidine dimer excision in UV-sensitive CHO mutants and the effect of the human ERCC2 repair gene.

Authors:  J D Regan; L H Thompson; W L Carrier; C A Weber; A A Francis; M Z Zdzienicka
Journal:  Mutat Res       Date:  1990-05       Impact factor: 2.433

4.  A promising genomic transfectant into Xeroderma pigmentosum group A with highly amplified mouse DNA and intermediate UV resistance turns revertant.

Authors:  M Blum; I Baumann; H Lohrer; H J Rahmsdorf; P Herrlich
Journal:  Biochem Biophys Res Commun       Date:  1989-04-28       Impact factor: 3.575

5.  An eighth complementation group of rodent cells hypersensitive to ultraviolet radiation.

Authors:  L H Thompson; T Shiomi; E P Salazar; S A Stewart
Journal:  Somat Cell Mol Genet       Date:  1988-11

6.  DNA cross-linking and monoadduct repair in nitrosourea-treated human tumour cells.

Authors:  L C Erickson; G Laurent; N A Sharkey; K W Kohn
Journal:  Nature       Date:  1980-12-25       Impact factor: 49.962

7.  Genetic diversity of UV-sensitive DNA repair mutants of Chinese hamster ovary cells.

Authors:  L H Thompson; D B Busch; K Brookman; C L Mooney; D A Glaser
Journal:  Proc Natl Acad Sci U S A       Date:  1981-06       Impact factor: 11.205

8.  Ataxia telangiectasia resists gene cloning: an account of parameters determining gene transfer into human recipient cells.

Authors:  H Lohrer; M Blum; P Herrlich
Journal:  Mol Gen Genet       Date:  1988-06

9.  Reduction of the toxicity and mutagenicity of alkylating agents in mammalian cells harboring the Escherichia coli alkyltransferase gene.

Authors:  J Brennand; G P Margison
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

10.  Quantitative comparison of carcinogenicity, mutagenicity and electrophilicity of 10 direct-acting alkylating agents and of the initial O6:7-alkylguanine ratio in DNA with carcinogenic potency in rodents.

Authors:  H Bartsch; B Terracini; C Malaveille; L Tomatis; J Wahrendorf; G Brun; B Dodet
Journal:  Mutat Res       Date:  1983-08       Impact factor: 2.433
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  2 in total

Review 1.  Programming of Cell Resistance to Genotoxic and Oxidative Stress.

Authors:  Ilya O Velegzhaninov; Vitaly A Ievlev; Yana I Pylina; Dmitry M Shadrin; Olesya M Vakhrusheva
Journal:  Biomedicines       Date:  2018-01-02

2.  Microcolony Size Distribution Assay Enables High-Throughput Cell Survival Quantitation.

Authors:  Le P Ngo; Tze Khee Chan; Jing Ge; Leona D Samson; Bevin P Engelward
Journal:  Cell Rep       Date:  2019-02-05       Impact factor: 9.423
  2 in total

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