Literature DB >> 30138095

Evaluation of an enhanced recovery protocol on patients having radical cystectomy for bladder cancer.

Bonnie Liu1, Trustin Domes2, Kunal Jana2.   

Abstract

INTRODUCTION: Enhanced recovery after surgery (ERAS) protocols are multimodal perioperative care protocols that are designed to shorten recovery time and reduce complication rates.1,2 An ERAS protocol was implemented in the Saskatoon Health region for radical cystectomy patients in 2013. This study evaluates the safety and efficacy of the protocol for patients having radical cystectomy for bladder cancer.
METHODS: Length of stay, early in-hospital complication rates, 30-day readmission rates, age, and gender were collected for patients seen for bladder cancer requiring radical cystectomy in Saskatoon between January 2007 and December 2016. Of these patients, 176 were pre-ERAS implementation (control group) and 84 were post-ERAS implementation (experimental group). The data from each variable was compared between the groups using a Z-test.
RESULTS: There was no significant difference in age or gender of patients between the groups. Average length of stay pre-ERAS was 14.25±14.57 days, which is significantly longer than the post-ERAS average of 10.91±8.56 days (p=0.043). There was no significant difference in 30-day readmission rate (19.87% pre-ERAS vs. 19.05% post-ERAS; p=0.873) or complication rate (51.7% pre-ERAS vs. 46.4% post-ERAS; p=0.425).
CONCLUSIONS: The implementation of an ERAS protocol for radical cystectomy reduces length of stay, with no effect on early complication rates or 30-day readmission rates. This indicates that the protocol is safe for patients when compared to previous practices and is an effective means of reducing length of stay.

Entities:  

Year:  2018        PMID: 30138095      PMCID: PMC6261727          DOI: 10.5489/cuaj.5273

Source DB:  PubMed          Journal:  Can Urol Assoc J        ISSN: 1911-6470            Impact factor:   1.862


  24 in total

1.  Challenging boundaries: an enhanced recovery programme for radical cystectomy.

Authors:  S Mukhtar; B E Ayres; R Issa; M J Swinn; M J A Perry
Journal:  Ann R Coll Surg Engl       Date:  2013-04       Impact factor: 1.891

2.  90-Day complication rate in patients undergoing radical cystectomy with enhanced recovery protocol: a prospective cohort study.

Authors:  Hooman Djaladat; Behrod Katebian; Soroush T Bazargani; Gus Miranda; Jie Cai; Anne K Schuckman; Siamak Daneshmand
Journal:  World J Urol       Date:  2016-10-12       Impact factor: 4.226

Review 3.  The Future of Enhanced Recovery for Radical Cystectomy: Current Evidence, Barriers to Adoption, and the Next Steps.

Authors:  Bernard J Danna; Erika L Wood; Janet E Baack Kukreja; Jay B Shah
Journal:  Urology       Date:  2016-05-06       Impact factor: 2.649

4.  Enhanced recovery after surgery (ERAS) protocols: Time to change practice?

Authors:  Megan Melnyk; Rowan G Casey; Peter Black; Anthony J Koupparis
Journal:  Can Urol Assoc J       Date:  2011-10       Impact factor: 1.862

5.  Evolution of the Southampton Enhanced Recovery Programme for radical cystectomy and the aggregation of marginal gains.

Authors:  Julian Smith; Zhao Wu Meng; Richard Lockyer; Tim Dudderidge; John McGrath; Matthew Hayes; Brian Birch
Journal:  BJU Int       Date:  2014-07-27       Impact factor: 5.588

6.  Enhanced recovery protocol after radical cystectomy for bladder cancer.

Authors:  Siamak Daneshmand; Hamed Ahmadi; Anne K Schuckman; Anirban P Mitra; Jie Cai; Gus Miranda; Hooman Djaladat
Journal:  J Urol       Date:  2014-02-08       Impact factor: 7.450

7.  Introduction of an enhanced recovery protocol for radical cystectomy.

Authors:  Nimalan Arumainayagam; John McGrath; Kieran P Jefferson; David A Gillatt
Journal:  BJU Int       Date:  2008-01-08       Impact factor: 5.588

8.  Updated 2016 EAU Guidelines on Muscle-invasive and Metastatic Bladder Cancer.

Authors:  J Alfred Witjes; Thierry Lebret; Eva M Compérat; Nigel C Cowan; Maria De Santis; Harman Maxim Bruins; Virginia Hernández; Estefania Linares Espinós; James Dunn; Mathieu Rouanne; Yann Neuzillet; Erik Veskimäe; Antoine G van der Heijden; Georgios Gakis; Maria J Ribal
Journal:  Eur Urol       Date:  2016-06-30       Impact factor: 20.096

9.  Enhanced recovery after surgery: are we ready, and can we afford not to implement these pathways for patients undergoing radical cystectomy?

Authors:  Hitendra R H Patel; Yannick Cerantola; Massimo Valerio; Beata Persson; Patrice Jichlinski; Olle Ljungqvist; Martin Hubner; Wassim Kassouf; Stig Müller; Gabriele Baldini; Francesco Carli; Torvind Naesheim; Lars Ytrebo; Arthur Revhaug; Kristoffer Lassen; Tore Knutsen; Erling Aarsaether; Peter Wiklund; James W F Catto
Journal:  Eur Urol       Date:  2013-10-22       Impact factor: 20.096

Review 10.  Systematic review and meta-analysis of enhanced recovery programmes in surgical patients.

Authors:  A Nicholson; M C Lowe; J Parker; S R Lewis; P Alderson; A F Smith
Journal:  Br J Surg       Date:  2014-02       Impact factor: 6.939

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  6 in total

1.  Mortality after radical cystectomy is strongly related to the institution's volume of surgeries.

Authors:  Fernando Korkes; Frederico Timóteo Silva Cunha; Matheus Prado Nascimento; Antonio Flávio Silva Rodrigues; Willy Baccaglini; Sidney Glina
Journal:  Einstein (Sao Paulo)       Date:  2020-12-07

Review 2.  Enhanced recovery after surgery of patients undergoing radical cystectomy for bladder cancer.

Authors:  Luck Hee Sung; Hyeong Dong Yuk
Journal:  Transl Androl Urol       Date:  2020-12

3.  Early recovery after surgery for radical cystectomy: comprehensive assessment and meta-analysis of existing protocols.

Authors:  F Wessels; M Lenhart; K F Kowalewski; V Braun; T Terboven; F Roghmann; M S Michel; P Honeck; M C Kriegmair
Journal:  World J Urol       Date:  2020-03-02       Impact factor: 4.226

4.  Short-term morbidity and mortality following radical cystectomy: a systematic review.

Authors:  Sophia Liff Maibom; Ulla Nordström Joensen; Alicia Martin Poulsen; Henrik Kehlet; Klaus Brasso; Martin Andreas Røder
Journal:  BMJ Open       Date:  2021-04-14       Impact factor: 2.692

5.  ERAS vs. Traditional Protocol in Patients Who Had Radical Cystectomy with Ileal Conduit: A Retrospective Comparative Analysis of 182 Cases.

Authors:  Ahmet Semih Guleser; Yasar Basaga
Journal:  Adv Urol       Date:  2022-02-28

6.  Population-Based Assessment of Determining Predictors for Discharge Disposition in Patients with Bladder Cancer Undergoing Radical Cystectomy.

Authors:  Raj A Kumar; Kian Asanad; Gus Miranda; Jie Cai; Hooman Djaladat; Saum Ghodoussipour; Mihir M Desai; Inderbir S Gill; Giovanni E Cacciamani
Journal:  Cancers (Basel)       Date:  2022-09-23       Impact factor: 6.575

  6 in total

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