Literature DB >> 18190646

Introduction of an enhanced recovery protocol for radical cystectomy.

Nimalan Arumainayagam1, John McGrath, Kieran P Jefferson, David A Gillatt.   

Abstract

OBJECTIVE: To describe and assess an enhanced recovery protocol (ERP) for the peri-operative management of patients undergoing radical cystectomy (RC), which was started at our institution on 1 October 2005, as RC is associated with increased morbidity and longer inpatient stays than other major urological procedures. PATIENTS AND METHODS: An ERP was introduced in our institution that focused on reduced bowel preparation, and standardized feeding and analgesic regimens. In all, 112 consecutive patients were compared, i.e. 56 before implementing the ERP and 56 since introducing the ERP. The primary outcome measures were duration of total inpatient stay and interval from surgery to discharge, and the morbidity and mortality. Data were analysed retrospectively from cancer network and hospital records.
RESULTS: The demographics of the two groups showed no significant difference in age, gender distribution, American Society of Anesthesiologists grade, or type of urinary diversion. Re-admission, mortality and morbidity rates showed no statistically significant difference between the groups. The median (interquartile range) duration of hospital stay was 17 (15-23) days in the no-ERP group, and 13 (11-17) days in the ERP group (significantly different, P < 0.001, Wilcoxon rank-sum test). The median duration of recovery after RC was 15 (13-21) days in the no-ERP group and 12 (10-15) days in the ERP group (significantly different, P = 0.001, Wilcoxon rank-sum test).
CONCLUSION: The introduction of an ERP was associated with significantly reduced hospital stay, with no deleterious effect on morbidity or mortality.

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Mesh:

Year:  2008        PMID: 18190646     DOI: 10.1111/j.1464-410X.2007.07319.x

Source DB:  PubMed          Journal:  BJU Int        ISSN: 1464-4096            Impact factor:   5.588


  40 in total

Review 1.  [Advanced bladder cancer in elderly patients. Prognostic outcomes and therapeutic strategies].

Authors:  M Rink; F K Chun; T F Chromecki; H Fajkovic; R Dahlem; M Fisch; S F Shariat
Journal:  Urologe A       Date:  2012-06       Impact factor: 0.639

Review 2.  [Fast-track concepts in the perioperative management of patients undergoing radical cystectomy and urinary diversion: review of the literature and research results].

Authors:  P J Olbert; L Baumann; A Hegele; A J Schrader; R Hofmann
Journal:  Urologe A       Date:  2009-02       Impact factor: 0.639

3.  Challenging boundaries: an enhanced recovery programme for radical cystectomy.

Authors:  S Mukhtar; B E Ayres; R Issa; M J Swinn; M J A Perry
Journal:  Ann R Coll Surg Engl       Date:  2013-04       Impact factor: 1.891

Review 4.  Fast-track surgery: procedure-specific aspects and future direction.

Authors:  Daniel Ansari; Luca Gianotti; Jörg Schröder; Roland Andersson
Journal:  Langenbecks Arch Surg       Date:  2012-09-27       Impact factor: 3.445

Review 5.  Enhanced recovery programmes for patients undergoing radical cystectomy.

Authors:  Julian Smith; Raj S Pruthi; John McGrath
Journal:  Nat Rev Urol       Date:  2014-07-15       Impact factor: 14.432

6.  Concurrent upper and lower urinary tract robotic surgery: A case series.

Authors:  Sailaja Pisipati; Christian Bach; Datesh Daneshwar; Edward W Rowe; Anthony J Koupparis
Journal:  Can Urol Assoc J       Date:  2014-11       Impact factor: 1.862

Review 7.  New perioperative fluid and pharmacologic management protocol results in reduced blood loss, faster return of bowel function, and overall recovery.

Authors:  Patrick Y Wuethrich; Fiona C Burkhard
Journal:  Curr Urol Rep       Date:  2015-04       Impact factor: 3.092

Review 8.  An Update in Enhanced Recovery Following Radical Cystectomy.

Authors:  Saum Ghodoussipour; Hooman Djaladat
Journal:  Curr Urol Rep       Date:  2018-10-18       Impact factor: 3.092

9.  Evaluation of an enhanced recovery protocol on patients having radical cystectomy for bladder cancer.

Authors:  Bonnie Liu; Trustin Domes; Kunal Jana
Journal:  Can Urol Assoc J       Date:  2018-07-31       Impact factor: 1.862

Review 10.  Enhanced Recovery after Urological Surgery: A Contemporary Systematic Review of Outcomes, Key Elements, and Research Needs.

Authors:  Raed A Azhar; Bernard Bochner; James Catto; Alvin C Goh; John Kelly; Hiten D Patel; Raj S Pruthi; George N Thalmann; Mihir Desai
Journal:  Eur Urol       Date:  2016-03-09       Impact factor: 20.096

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