Stefano Marcia1, Mario Muto2, Joshua A Hirsch3, Ronil V Chandra4, Nicole Carter4, Paola Crivelli5, Emanuele Piras1, Luca Saba6,7. 1. Radiology Department SS Trinità Hospital, ATS Sardegna, ASSL Cagliari, Cagliari, Italy. 2. Neuroradiology Department, Ospedale Cardarelli, Via Antonio Cardarelli 9, 80100, Naples, Italy. 3. Neuroendovascular Program, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. 4. Interventional Neuroradiology Unit, Monash Imaging, Monash Health, Melbourne, Australia and Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia. 5. Department of Radiology, University of Sassari, Sassari, Italy. 6. Department of Radiology, University of Cagliari, Cagliari, Italy. lucasaba@tiscali.it. 7. Department of Radiology, Azienda Ospedaliero Universitaria of Cagliari, SS 554 Monserrato, Cagliari, Italy. lucasaba@tiscali.it.
Abstract
PURPOSE: Vertebral augmentation procedures such as vertebroplasty and kyphoplasty are utilized in the treatment of vertebral compression fractures (VCFs). However, their capacity for providing analgesia, reducing disability, and improving quality of life in patients with osteoporotic VCFs remains a topic of debate. The objective of this narrative review is to summarize the latest evidence for the safety and efficacy of vertebral augmentation for osteoporotic vertebral compression fractures (VCFs). METHODS: A systematic literature search was conducted using the PubMed and Cochrane electronic databases for systematic reviews, review articles, meta-analyses, and randomized clinical trials prior to May 2017. The keywords were "vertebroplasty," "kyphoplasty," and "vertebral augmentation." RESULTS: Thirty-three papers (7 systematic reviews, 6 cohort studies, 15 randomized clinical trials, and 5 international guidelines) were included in this narrative review. CONCLUSION: Vertebral augmentation is a safe procedure, with low rates of serious complications and no increase in subsequent post-treatment fracture risk.
PURPOSE: Vertebral augmentation procedures such as vertebroplasty and kyphoplasty are utilized in the treatment of vertebral compression fractures (VCFs). However, their capacity for providing analgesia, reducing disability, and improving quality of life in patients with osteoporotic VCFs remains a topic of debate. The objective of this narrative review is to summarize the latest evidence for the safety and efficacy of vertebral augmentation for osteoporotic vertebral compression fractures (VCFs). METHODS: A systematic literature search was conducted using the PubMed and Cochrane electronic databases for systematic reviews, review articles, meta-analyses, and randomized clinical trials prior to May 2017. The keywords were "vertebroplasty," "kyphoplasty," and "vertebral augmentation." RESULTS: Thirty-three papers (7 systematic reviews, 6 cohort studies, 15 randomized clinical trials, and 5 international guidelines) were included in this narrative review. CONCLUSION: Vertebral augmentation is a safe procedure, with low rates of serious complications and no increase in subsequent post-treatment fracture risk.
Authors: Steven Boonen; Jan Van Meirhaeghe; Leonard Bastian; Steven R Cummings; Jonas Ranstam; John B Tillman; Richard Eastell; Karen Talmadge; Douglas Wardlaw Journal: J Bone Miner Res Date: 2011-07 Impact factor: 6.741
Authors: Jordi Blasco; Angeles Martinez-Ferrer; Juan Macho; Luis San Roman; Jaume Pomés; Josep Carrasco; Ana Monegal; Nuria Guañabens; Pilar Peris Journal: J Bone Miner Res Date: 2012-05 Impact factor: 6.741
Authors: William Clark; Paul Bird; Peter Gonski; Terrence H Diamond; Peter Smerdely; H Patrick McNeil; Glen Schlaphoff; Carl Bryant; Elizabeth Barnes; Val Gebski Journal: Lancet Date: 2016-08-17 Impact factor: 79.321
Authors: Bryan A Comstock; Colleen M Sitlani; Jeffrey G Jarvik; Patrick J Heagerty; Judith A Turner; David F Kallmes Journal: Radiology Date: 2013-05-21 Impact factor: 11.105
Authors: Laxmaiah Manchikanti; Nebojsa Nick Knezevic; Mark V Boswell; Alan D Kaye; Joshua A Hirsch Journal: Pain Physician Date: 2016-03 Impact factor: 4.965