Literature DB >> 29926148

Osteoarthritis is associated with increased failure of proximal femoral fracture fixation.

Charles A Gallagher1, Christopher W Jones2, Lara Kimmel3,4, Christopher Wylde2, Anthony Osbrough2, Max Bulsara5, Kathryn Hird6, Piers Yates2.   

Abstract

PURPOSE: The purpose of this study was to evaluate whether the presence of hip osteoarthritis at the time of hip fracture increases treatment failure rates when using either a sliding hip screw (SHS) or proximal femoral nail (PFN) for fracture fixation.
METHODS: A retrospective study of a consecutive series of 455 women and 148 men (median age, 83.8 years) treated with SHS or PFN was performed. Osteoarthritis was evaluated based on pre-operative radiographs using the Kellgren and Lawrence grading system. Treatment failure, which was defined as non-union, avascular necrosis, backing out of the implant, cut out of the proximal screws, peri-prosthetic fracture, implant breakage, or conversion to hemi- or total hip arthroplasty, was evaluated for a follow-up period of four to seven years. Optimal placement of the implant (tip-apex distance (TAD) and 3-point fixation) and the effects of age, sex, the quality of reduction, implant type, fracture stability, fracture type, and time to failure were considered confounders of the relationship between failure and osteoarthritis (OA).
RESULTS: Among the 32 cases (5.3%) of treatment failure, 12 (2%) showed evidence of osteoarthritis. After controlling for age, sex, the quality of reduction, implant type, fracture stability, fracture type, and TAD, osteoarthritis was associated a greater than threefold increase in treatment failure compared with that of patients without pre-operative evidence of osteoarthritis (OR, 3.26; 95% CI, 1.4-7.65; P = 0.006).
CONCLUSIONS: After adjusting for potential confounding factors, radiographic evidence of hip osteoarthritis at the time of hip fracture increases the incidence of treatment failure.

Entities:  

Keywords:  Failure; Fracture; Hip; Neck of femur; Osteoarthritis; Treatment

Mesh:

Year:  2018        PMID: 29926148     DOI: 10.1007/s00264-018-4014-8

Source DB:  PubMed          Journal:  Int Orthop        ISSN: 0341-2695            Impact factor:   3.075


  26 in total

1.  Fracture and Dislocation Classification Compendium-2018

Authors:  Eric G Meinberg; Julie Agel; Craig S Roberts; Matthew D Karam; James F Kellam
Journal:  J Orthop Trauma       Date:  2018-01       Impact factor: 2.512

2.  Costs and Complications of Short Versus Long Cephalomedullary Nailing of OTA 31-A2 Proximal Femur Fractures in U.S. Veterans.

Authors:  Henry Krigbaum; Steven Takemoto; Hubert T Kim; Alfred C Kuo
Journal:  J Orthop Trauma       Date:  2016-03       Impact factor: 2.512

3.  Which factor is most important for occurrence of cutout complications in patients treated with proximal femoral nail antirotation? Retrospective analysis of 298 patients.

Authors:  Ali Turgut; Önder Kalenderer; Levent Karapınar; Mert Kumbaracı; Hasan Ali Akkan; Haluk Ağuş
Journal:  Arch Orthop Trauma Surg       Date:  2016-02-06       Impact factor: 3.067

4.  Intertrochanteric femoral fractures. Mechanical failure after internal fixation.

Authors:  T R Davis; J L Sher; A Horsman; M Simpson; B B Porter; R G Checketts
Journal:  J Bone Joint Surg Br       Date:  1990-01

5.  Risk factors in cutout of sliding hip screw in intertrochanteric fractures: an evaluation of 937 patients.

Authors:  Kuang-Kai Hsueh; Chi-Kuang Fang; Chuan-Mu Chen; Yu-Ping Su; Heng-Fei Wu; Fang-Yao Chiu
Journal:  Int Orthop       Date:  2009-09-26       Impact factor: 3.075

Review 6.  Advances in the treatment of intracapsular hip fractures in the elderly.

Authors:  Ross K Leighton; Andrew H Schmidt; Pamela Collier; Kelly Trask
Journal:  Injury       Date:  2007-09       Impact factor: 2.586

7.  Inadequate 'three-point' proximal fixation predicts failure of the Gamma nail.

Authors:  S G F Abram; T C B Pollard; A J M D Andrade
Journal:  Bone Joint J       Date:  2013-06       Impact factor: 5.082

8.  Osteoarthritis protects against femoral neck fracture: the MEDOS study experience.

Authors:  J Dequeker; O Johnell
Journal:  Bone       Date:  1993       Impact factor: 4.398

9.  The association between hip fracture and hip osteoarthritis: a case-control study.

Authors:  Jonas Franklin; Martin Englund; Torvaldur Ingvarsson; Stefan Lohmander
Journal:  BMC Musculoskelet Disord       Date:  2010-11-26       Impact factor: 2.362

10.  Impact of hip fracture on hospital care costs: a population-based study.

Authors:  J Leal; A M Gray; D Prieto-Alhambra; N K Arden; C Cooper; M K Javaid; A Judge
Journal:  Osteoporos Int       Date:  2015-08-19       Impact factor: 4.507

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  4 in total

1.  A decade of Australian and New Zealand orthopaedic publications: a bibliometric trend analysis from 2008 to 2018.

Authors:  Agesilaus W Churchill; Eva Malacova; Simon F Journeaux; Martin Richardson; Ross Crawford; Mark L Vickers
Journal:  Int Orthop       Date:  2019-06-26       Impact factor: 3.075

2.  Proximal femoral nailing is superior to hemiarthroplasty in AO/OTA A2 and A3 intertrochanteric femur fractures in the elderly: a systematic literature review and meta-analysis.

Authors:  Prasoon Kumar; Rajesh Kumar Rajnish; Siddhartha Sharma; Mandeep Singh Dhillon
Journal:  Int Orthop       Date:  2019-06-14       Impact factor: 3.075

Review 3.  Management of subtrochanteric fractures by nail osteosynthesis: a review of tips and tricks.

Authors:  Srinivas Kasha; Ranjith Kumar Yalamanchili
Journal:  Int Orthop       Date:  2019-09-16       Impact factor: 3.075

4.  miR-7/EGFR/MEGF9 axis regulates cartilage degradation in osteoarthritis via PI3K/AKT/mTOR signaling pathway.

Authors:  Lifeng Jiang; Xindie Zhou; Kai Xu; Pengfei Hu; Jiapeng Bao; Jin Li; Junfeng Zhu; Lidong Wu
Journal:  Bioengineered       Date:  2021-12       Impact factor: 3.269

  4 in total

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