Literature DB >> 29755163

Design verification of a compact system for detecting tissue perfusion using bimodal diffuse optical technologies.

Julia M Pakela1, Taylor L Hedrick1, Seung Yup Lee1, Karthik Vishwanath2, Sara Zanfardino2, Yooree G Chung1, Michael C Helton1, Noah J Kolodziejski3, Christopher J Stapels3, Daniel R McAdams3, Daniel E Fernandez3, James F Christian3, Stephen E Feinberg1, Mary-Ann Mycek1.   

Abstract

It is essential to monitor tissue perfusion during and after reconstructive surgery, as restricted blood flow can result in graft failures. Current clinical procedures are insufficient to monitor tissue perfusion, as they are intermittent and often subjective. To address this unmet clinical need, a compact, low-cost, multimodal diffuse correlation spectroscopy and diffuse reflectance spectroscopy system was developed. We verified system performance via tissue phantoms and experimental protocols for rigorous bench testing. Quantitative data analysis methods were employed and tested to enable the extraction of tissue perfusion parameters. This design verification study assures data integrity in future in vivo studies.

Entities:  

Keywords:  Diffuse Correlation Spectroscopy; Diffuse Reflectance Spectroscopy; tissue perfusion; tissue phantoms

Year:  2017        PMID： 29755163      PMCID： PMC5946689          DOI： 10.1117/12.2252811

Source DB:  PubMed          Journal:  Proc SPIE Int Soc Opt Eng        ISSN： 0277-786X


  9 in total

1.  Scattering and Imaging with Diffusing Temporal Field Correlations.

Authors: 
Journal:  Phys Rev Lett       Date:  1995-08-28       Impact factor: 9.161

2.  Monte Carlo lookup table-based inverse model for extracting optical properties from tissue-simulating phantoms using diffuse reflectance spectroscopy.

Authors:  Ricky Hennessy; Sam L Lim; Mia K Markey; James W Tunnell
Journal:  J Biomed Opt       Date:  2013-03       Impact factor: 3.170

3.  A scalable correlator for multichannel diffuse correlation spectroscopy.

Authors:  Christopher J Stapels; Noah J Kolodziejski; Daniel McAdams; Matthew J Podolsky; Daniel E Fernandez; Dana Farkas; James F Christian
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2016-03-07

4.  A disposable, flexible skin patch for clinical optical perfusion monitoring at multiple depths.

Authors:  Dana L Farkas; Noah J Kolodziejski; Christopher J Stapels; Daniel R McAdams; Daniel E Fernandez; Matthew J Podolsky; James F Christian; Brent B Ward; Mark Vartarian; Stephen E Feinberg; Seung Yup Lee; Urmi Parikh; Mary-Ann Mycek; Michael J Joyner; Christopher P Johnson; Norman A Paradis
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2016-03-04

5.  A compact instrument to measure perfusion of vasculature in transplanted maxillofacial free flaps.

Authors:  Noah J Kolodziejski; Christopher J Stapels; Daniel R McAdams; Daniel E Fernandez; Matthew J Podolsky; Dana Farkas; Brent B Ward; Mark Vartarian; Stephen E Feinberg; Seung Yup Lee; Urmi Parikh; Mary-Ann Mycek; James F Christian
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2016-03-04

6.  Diffuse correlation spectroscopy for measurement of cerebral blood flow: future prospects.

Authors:  Erin M Buckley; Ashwin B Parthasarathy; P Ellen Grant; Arjun G Yodh; Maria Angela Franceschini
Journal:  Neurophotonics       Date:  2014-06-20       Impact factor: 3.593

Review 7.  Diffuse correlation spectroscopy for non-invasive, micro-vascular cerebral blood flow measurement.

Authors:  Turgut Durduran; Arjun G Yodh
Journal:  Neuroimage       Date:  2013-06-14       Impact factor: 6.556

8.  Instrument to detect syncope and the onset of shock.

Authors:  Daniel R McAdams; Noah J Kolodziejski; Christopher J Stapels; Daniel E Fernandez; Matthew J Podolsky; Dana Farkas; James F Christian; Michael J Joyner; Christopher P Johnson; Norman A Paradis
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2016-03-17

9.  Assessment of the best flow model to characterize diffuse correlation spectroscopy data acquired directly on the brain.

Authors:  Kyle Verdecchia; Mamadou Diop; Laura B Morrison; Ting-Yim Lee; Keith St Lawrence
Journal:  Biomed Opt Express       Date:  2015-10-07       Impact factor: 3.732
  9 in total

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