| Literature DB >> 23770408 |
Turgut Durduran1, Arjun G Yodh.
Abstract
Diffuse correlation spectroscopy (DCS) uses the temporal fluctuations of near-infrared (NIR) light to measure cerebral blood flow (CBF) non-invasively. Here, we provide a brief history of DCS applications in the brain with an emphasis on the underlying physical ideas, common instrumentation and validation. Then we describe recent clinical research that employs DCS-measured CBF as a biomarker of patient well-being, and as an indicator of hemodynamic and metabolic responses to functional stimuli.Entities:
Keywords: Cerebral blood flow; Cerebral metabolic rate of oxygen extraction; Diffuse correlation spectroscopy; Diffuse optics; Functional neuroimaging; Ischemic stroke; Near-infrared spectroscopy; Neonatalogy; Neurocritical care
Mesh:
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Year: 2013 PMID: 23770408 PMCID: PMC3991554 DOI: 10.1016/j.neuroimage.2013.06.017
Source DB: PubMed Journal: Neuroimage ISSN: 1053-8119 Impact factor: 6.556