| Literature DB >> 29056813 |
Dana L Farkas1,2, Noah J Kolodziejski2, Christopher J Stapels2, Daniel R McAdams2, Daniel E Fernandez2, Matthew J Podolsky2, James F Christian2, Brent B Ward3, Mark Vartarian3, Stephen E Feinberg3, Seung Yup Lee3, Urmi Parikh3, Mary-Ann Mycek3, Michael J Joyner4, Christopher P Johnson4, Norman A Paradis5.
Abstract
Stable, relative localization of source and detection fibers is necessary for clinical implementation of quantitative optical perfusion monitoring methods such as diffuse correlation spectroscopy (DCS) and diffuse reflectance spectroscopy (DRS). A flexible and compact device design is presented as a platform for simultaneous monitoring of perfusion at a range of depths, enabled by precise location of optical fibers in a robust and secure adhesive patch. We will discuss preliminary data collected on human subjects in a lower body negative pressure model for hypovolemic shock. These data indicate that this method facilitates simple and stable simultaneous monitoring of perfusion at multiple depths and within multiple physiological compartments.Entities:
Keywords: DCS; DRS; Optical perfusion monitoring; diffuse correlation spectroscopy; diffuse reflectance spectroscopy; hemorrhagic shock; noninvasive
Year: 2016 PMID： 29056813 PMCID： PMC5647776 DOI： 10.1117/12.2230988
Source DB: PubMed Journal: Proc SPIE Int Soc Opt Eng ISSN： 0277-786X