| Literature DB >> 29736000 |
Oliver Skocek1, Tobias Nöbauer1, Lukas Weilguny2, Francisca Martínez Traub1, Chuying Naomi Xia1, Maxim I Molodtsov2, Abhinav Grama3,4, Masahito Yamagata3,4, Daniel Aharoni5, David D Cox3,4, Peyman Golshani5,6,7, Alipasha Vaziri8,9,10.
Abstract
Thus far, optical recording of neuronal activity in freely behaving animals has been limited to a thin axial range. We present a head-mounted miniaturized light-field microscope (MiniLFM) capable of capturing neuronal network activity within a volume of 700 × 600 × 360 µm3 at 16 Hz in the hippocampus of freely moving mice. We demonstrate that neurons separated by as little as ~15 µm and at depths up to 360 µm can be discriminated.Entities:
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Year: 2018 PMID： 29736000 PMCID： PMC7990085 DOI： 10.1038/s41592-018-0008-0
Source DB: PubMed Journal: Nat Methods ISSN： 1548-7091 Impact factor: 28.547