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Literature DB >> 29453649

Reinereins A and B, new onocerane triterpenoids from Reinwardtiodendron cinereum.

Alfarius Eko Nugroho¹, Daisuke Inoue¹, Chin Piow Wong¹, Yusuke Hirasawa¹, Toshio Kaneda¹, Osamu Shirota², A Hamid A Hadi³, Hiroshi Morita⁴.

Abstract

Bioactivity guided separation of Reinwardtiodendron cinereum barks methanol extract led to the isolation of two new onocerane triterpenoids, reinereins A and B (1 and 2), together with three known onocerane triterpenoids. Their structures were elucidated on the basis of NMR spectroscopic data. In vitro cytotoxic activities of the isolated compounds against several type of cancer cells were evaluated.

Entities: Chemical Disease Species

Keywords: Cytotoxicity; Meliaceae; Onocerane; Reinwardtiodendron cinereum; Triterpenoid

Mesh：

Substances：
Triterpenes

Year: 2018 PMID： 29453649 DOI： 10.1007/s11418-018-1188-8

Source DB: PubMed Journal: J Nat Med ISSN： 1340-3443 Impact factor: 2.343

14 in total

1. Chrotacumines G-J, chromone alkaloids from Dysoxylum acutangulum with osteoclast differentiation inhibitory activity.

Authors: Hiroshi Morita; Alfarius Eko Nugroho; Yuta Nagakura; Yusuke Hirasawa; Haruka Yoshida; Toshio Kaneda; Osamu Shirota; Intan Safinar Ismail
Journal: Bioorg Med Chem Lett Date: 2014-04-13 Impact factor: 2.823

2. Aglaia (Meliaceae): an evaluation of taxonomic concepts based on DNA data and secondary metabolites.

Authors: Alexandra N Muellner; Rosabelle Samuel; Mark W Chase; Caroline M Pannell; Harald Greger
Journal: Am J Bot Date: 2005-03 Impact factor: 3.844

3. Dysosesquiflorins A and B, sesquiterpenoids from Dysoxylum densiflorum.

Authors: Alfarius E Nugroho; Rio Sugiura; Takanori Momota; Yusuke Hirasawa; Chin Piow Wong; Toshio Kaneda; A Hamid A Hadi; Hiroshi Morita
Journal: J Nat Med Date: 2015-02-07 Impact factor: 2.343

4. Bisnicalaterines B and C, atropisomeric bisindole alkaloids from Hunteria zeylanica, showing vasorelaxant activity.

Authors: Yusuke Hirasawa; Mayumi Hara; Alfarius E Nugroho; Masatomo Sugai; Kazumasa Zaima; Nobuo Kawahara; Yukihiro Goda; Khalijah Awang; A Hamid A Hadi; Marc Litaudon; Hiroshi Morita
Journal: J Org Chem Date: 2010-06-18 Impact factor: 4.354

5. Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii.

Authors: Yusuke Hirasawa; Tomokazu Shoji; Takashi Arai; Alfarius E Nugroho; Jun Deguchi; Takahiro Hosoya; Nahoko Uchiyama; Yukihiro Goda; Khalijah Awang; A Hamid A Hadi; Motoo Shiro; Hiroshi Morita
Journal: Bioorg Med Chem Lett Date: 2010-01-20 Impact factor: 2.823

6. Onoceranoid-type triterpenoids from Lansium domesticum.

Authors: Shi-Hui Dong; Chuan-Rui Zhang; Lei Dong; Yan Wu; Jian-Min Yue
Journal: J Nat Prod Date: 2011-03-14 Impact factor: 4.050

7. Opaciniols A-C, new terpenoids from Garcinia opaca.

Authors: Reika Mori; Alfarius Eko Nugroho; Yusuke Hirasawa; Chin Piow Wong; Toshio Kaneda; Osamu Shirota; A Hamid A Hadi; Hiroshi Morita
Journal: J Nat Med Date: 2013-03-28 Impact factor: 2.343

8. New onoceranoid triterpene constituents from Lansium domesticum.

Authors: Tadamitsu Tanaka; Masami Ishibashi; Haruhiro Fujimoto; Emi Okuyama; Takashi Koyano; Thaworn Kowithayakorn; Masahiko Hayashi; Kanki Komiyama
Journal: J Nat Prod Date: 2002-11 Impact factor: 4.050

9. Ceramicines from Chisocheton ceramicus as lipid-droplets accumulation inhibitors.

Authors: Chin Piow Wong; Jun Deguchi; Alfarius Eko Nugroho; Toshio Kaneda; A Hamid A Hadi; Hiroshi Morita
Journal: Bioorg Med Chem Lett Date: 2013-01-23 Impact factor: 2.823

10. Ceramicines M-P from Chisocheton ceramicus: isolation and structure-activity relationship study.

Authors: Alfarius Eko Nugroho; Akiyo Hashimoto; Chin-Piow Wong; Hiromasa Yokoe; Masayoshi Tsubuki; Toshio Kaneda; A Hamid A Hadi; Hiroshi Morita
Journal: J Nat Med Date: 2017-08-18 Impact factor: 2.343

5 in total

Review 1. Isolation and structure elucidation of constituents of Citrus limon, Isodon japonicus, and Lansium domesticum as the cancer prevention agents.

Authors: Takahiro Matsumoto; Tetsushi Watanabe
Journal: Genes Environ Date: 2020-04-16

Review 5. Isolation and structure elucidation of constituents of Citrus limon, Isodon japonicus, and Lansium domesticum as the cancer prevention agents.