Literature DB >> 24767841

Chrotacumines G-J, chromone alkaloids from Dysoxylum acutangulum with osteoclast differentiation inhibitory activity.

Hiroshi Morita1, Alfarius Eko Nugroho2, Yuta Nagakura2, Yusuke Hirasawa2, Haruka Yoshida2, Toshio Kaneda2, Osamu Shirota3, Intan Safinar Ismail4.   

Abstract

Four new chromone alkaloids, chrotacumines G-J (1-4), have been isolated from the barks of Dysoxylum acutangulum. Their structures and absolute configurations were elucidated on the basis of NMR and CD data. Chrotacumines G and J (1 and 4) showed osteoclast differentiation inhibitory activity in a dose dependent manner.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Activity; Alkaloids; Chrotacumines; Dysoxylum; Meliaceae

Mesh：

Substances：

Year:  2014        PMID： 24767841     DOI： 10.1016/j.bmcl.2014.04.020

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

1.  Dysosesquiflorins A and B, sesquiterpenoids from Dysoxylum densiflorum.

Authors:  Alfarius E Nugroho; Rio Sugiura; Takanori Momota; Yusuke Hirasawa; Chin Piow Wong; Toshio Kaneda; A Hamid A Hadi; Hiroshi Morita
Journal:  J Nat Med       Date:  2015-02-07       Impact factor: 2.343

2.  Leucophyllinines A and B, bisindole alkaloids from Leuconotis eugeniifolia.

Authors:  Yiming Tang; Alfarius Eko Nugroho; Yusuke Hirasawa; Takahiro Tougan; Toshihiro Horii; A Hamid A Hadi; Hiroshi Morita
Journal:  J Nat Med       Date:  2019-03-25       Impact factor: 2.343

3.  Reinereins A and B, new onocerane triterpenoids from Reinwardtiodendron cinereum.

Authors:  Alfarius Eko Nugroho; Daisuke Inoue; Chin Piow Wong; Yusuke Hirasawa; Toshio Kaneda; Osamu Shirota; A Hamid A Hadi; Hiroshi Morita
Journal:  J Nat Med       Date:  2018-02-16       Impact factor: 2.343
  3 in total

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