Literature DB >> 20469917

Bisnicalaterines B and C, atropisomeric bisindole alkaloids from Hunteria zeylanica, showing vasorelaxant activity.

Yusuke Hirasawa1, Mayumi Hara, Alfarius E Nugroho, Masatomo Sugai, Kazumasa Zaima, Nobuo Kawahara, Yukihiro Goda, Khalijah Awang, A Hamid A Hadi, Marc Litaudon, Hiroshi Morita.   

Abstract

Two new bisindole alkaloids, bisnicalaterines B and C (1 and 2) consisting of an eburnane and a corynanthe type of skeletons, were isolated from the bark of Hunteria zeylanica. Their absolute structures were determined by combination of NMR, CD, and computational methods, and each of them was shown to be in an atropisomeric relationship. Bisnicalaterines B and C (1 and 2) showed potent vasorelaxant activity on isolated rat aorta.

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Year:  2010        PMID： 20469917     DOI： 10.1021/jo1006762

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  14 in total

1.  Vasorelaxant effect of FR900359 from Ardisia crenata on rat aortic artery.

Authors:  Kazumasa Zaima; Jun Deguchi; Yosuke Matsuno; Toshio Kaneda; Yusuke Hirasawa; Hiroshi Morita
Journal:  J Nat Med       Date:  2012-03-03       Impact factor: 2.343

2.  Haworforbins A-C, new phenolics from Haworthia cymbiformis.

Authors:  Fumie Yamasaki; Shoko Machida; Asami Nakata; Alfarius Eko Nugroho; Yusuke Hirasawa; Toshio Kaneda; Osamu Shirota; Naoyuki Hagane; Tadayoshi Sugizaki; Hiroshi Morita
Journal:  J Nat Med       Date:  2012-03-16       Impact factor: 2.343

3.  Sanjecumins A and B: new limonoids from Sandoricum koetjape.

Authors:  Yuta Nagakura; Alfarius Eko Nugroho; Yusuke Hirasawa; Takahiro Hosoya; Abdul Rahman; Idha Kusumawati; Noor Cholies Zaini; Hiroshi Morita
Journal:  J Nat Med       Date:  2012-06-22       Impact factor: 2.343

4.  Antiplasmodial indole alkaloids from Leuconotis griffithii.

Authors:  Alfarius E Nugroho; Yusuke Hirasawa; Wong Chin Piow; Toshio Kaneda; A Hamid A Hadi; Osamu Shirota; Wiwied Ekasari; Aty Widyawaruyanti; Hiroshi Morita
Journal:  J Nat Med       Date:  2011-08-10       Impact factor: 2.343

5.  Vasorelaxant effect of isoquinoline derivatives from two species of Popowia perakensis and Phaeanthus crassipetalus on rat aortic artery.

Authors:  Kazumasa Zaima; Yuka Takeyama; Ikumi Koga; Aiko Saito; Haruka Tamamoto; Saripah Salbiah Syed Abd Azziz; Mat Ropi Mukhtar; Khalijah Awang; A Hamid A Hadi; Hiroshi Morita
Journal:  J Nat Med       Date:  2011-10-28       Impact factor: 2.343

6.  Two new sarpagine-type indole alkaloids and antimalarial activity of 16-demethoxycarbonylvoacamine from Tabernaemontana macrocarpa Jack.

Authors:  Puteri Amelia; Alfarius Eko Nugroho; Yusuke Hirasawa; Toshio Kaneda; Takahiro Tougan; Toshihiro Horii; Hiroshi Morita
Journal:  J Nat Med       Date:  2019-05-28       Impact factor: 2.343

7.  Nature-inspired stereospecific total synthesis of P-(+)-dispegatrine and four other monomeric sarpagine indole alkaloids.

Authors:  Chitra R Edwankar; Rahul V Edwankar; Jeffrey R Deschamps; James M Cook
Journal:  Angew Chem Int Ed Engl       Date:  2012-10-16       Impact factor: 15.336

8.  Reinereins A and B, new onocerane triterpenoids from Reinwardtiodendron cinereum.

Authors:  Alfarius Eko Nugroho; Daisuke Inoue; Chin Piow Wong; Yusuke Hirasawa; Toshio Kaneda; Osamu Shirota; A Hamid A Hadi; Hiroshi Morita
Journal:  J Nat Med       Date:  2018-02-16       Impact factor: 2.343

Review 9.  Circular dichroism calculation for natural products.

Authors:  Alfarius Eko Nugroho; Hiroshi Morita
Journal:  J Nat Med       Date:  2013-04-07       Impact factor: 2.343

10.  Stereospecific approach to the synthesis of ring-A oxygenated sarpagine indole alkaloids. Total synthesis of the dimeric indole alkaloid P-(+)-dispegatrine and six other monomeric indole alkaloids.

Authors:  Chitra R Edwankar; Rahul V Edwankar; Ojas A Namjoshi; Xuebin Liao; James M Cook
Journal:  J Org Chem       Date:  2013-06-18       Impact factor: 4.354
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