Literature DB >> 29333520

Application of epigenetic data in human health risk assessment.

Ila L Cote1, Shaun D McCullough2, Ronald N Hines2, John J Vandenberg3.   

Abstract

Despite the many recent advances in the field of epigenetics, application of this knowledge in environmental health risk assessment has been limited. In this paper, we identify opportunities for application of epigenetic data to support health risk assessment. We consider current applications and present a vision for the future.

Entities:  

Keywords:  Adverse outcome pathway; Environmental; Epigenetics; Epigenomic modifications; Mechanisms; Risk assessment

Year:  2017        PMID： 29333520      PMCID： PMC5759783          DOI： 10.1016/j.cotox.2017.09.002

Source DB:  PubMed          Journal:  Curr Opin Toxicol        ISSN： 2468-2020


  40 in total

1.  Identification of transcription complexes that contain the double bromodomain protein Brd2 and chromatin remodeling machines.

Authors:  Gerald V Denis; Mark E McComb; Douglas V Faller; Anupama Sinha; Paul B Romesser; Catherine E Costello
Journal:  J Proteome Res       Date:  2006-03       Impact factor: 4.466

2.  Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR).

Authors:  Evan M Kroh; Rachael K Parkin; Patrick S Mitchell; Muneesh Tewari
Journal:  Methods       Date:  2010-02-08       Impact factor: 3.608

3.  Epigenetic events determine tissue-specific toxicity of inhalational exposure to the genotoxic chemical 1,3-butadiene in male C57BL/6J mice.

Authors:  Grace Chappell; Tetyana Kobets; Bridget O'Brien; Natalia Tretyakova; Dewakar Sangaraju; Oksana Kosyk; Kenneth G Sexton; Wanda Bodnar; Igor P Pogribny; Ivan Rusyn
Journal:  Toxicol Sci       Date:  2014-09-18       Impact factor: 4.849

Review 4.  A Tox21 Approach to Altered Epigenetic Landscapes: Assessing Epigenetic Toxicity Pathways Leading to Altered Gene Expression and Oncogenic Transformation In Vitro.

Authors:  Craig L Parfett; Daniel Desaulniers
Journal:  Int J Mol Sci       Date:  2017-06-01       Impact factor: 5.923

Review 5.  Zebrafish as a model to study the role of DNA methylation in environmental toxicology.

Authors:  Jorke H Kamstra; Peter Aleström; Jan M Kooter; Juliette Legler
Journal:  Environ Sci Pollut Res Int       Date:  2014-08-31       Impact factor: 4.223

6.  Reprogramming of the Epigenome by MLL1 Links Early-Life Environmental Exposures to Prostate Cancer Risk.

Authors:  Quan Wang; Lindsey S Trevino; Rebecca Lee Yean Wong; Mario Medvedovic; Jing Chen; Shuk-Mei Ho; Jianjun Shen; Charles E Foulds; Cristian Coarfa; Bert W O'Malley; Ali Shilatifard; Cheryl L Walker
Journal:  Mol Endocrinol       Date:  2016-05-24

7.  High-throughput small molecule screen identifies inhibitors of aberrant chromatin accessibility.

Authors:  Samantha G Pattenden; Jeremy M Simon; Aminah Wali; Chatura N Jayakody; Jacob Troutman; Andrew W McFadden; Joshua Wooten; Cameron C Wood; Stephen V Frye; William P Janzen; Ian J Davis
Journal:  Proc Natl Acad Sci U S A       Date:  2016-02-29       Impact factor: 11.205

8.  Addressing human variability in next-generation human health risk assessments of environmental chemicals.

Authors:  Lauren Zeise; Frederic Y Bois; Weihsueh A Chiu; Dale Hattis; Ivan Rusyn; Kathryn Z Guyton
Journal:  Environ Health Perspect       Date:  2012-10-19       Impact factor: 9.031

9.  Microvesicle-associated microRNA expression is altered upon particulate matter exposure in healthy workers and in A549 cells.

Authors:  Valentina Bollati; Laura Angelici; Giovanna Rizzo; Laura Pergoli; Federica Rota; Mirjam Hoxha; Francesco Nordio; Matteo Bonzini; Letizia Tarantini; Laura Cantone; Angela C Pesatori; Pietro Apostoli; Andrea A Baccarelli; Pier Alberto Bertazzi
Journal:  J Appl Toxicol       Date:  2014-02-07       Impact factor: 3.446

10.  Long-term ambient particle exposures and blood DNA methylation age: findings from the VA normative aging study.

Authors:  Jamaji C Nwanaji-Enwerem; Elena Colicino; Letizia Trevisi; Itai Kloog; Allan C Just; Jincheng Shen; Kasey Brennan; Alexandra Dereix; Lifang Hou; Pantel Vokonas; Joel Schwartz; Andrea A Baccarelli
Journal:  Environ Epigenet       Date:  2016-06-12
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  2 in total

1.  Toxicoepigenetics for Risk Assessment: Bridging the Gap Between Basic and Regulatory Science.

Authors:  Anne Le Goff; Séverine Louvel; Henri Boullier; Patrick Allard
Journal:  Epigenet Insights       Date:  2022-07-15

2.  Leveraging human genetic and adverse outcome pathway (AOP) data to inform susceptibility in human health risk assessment.

Authors:  Holly M Mortensen; John Chamberlin; Bonnie Joubert; Michelle Angrish; Nisha Sipes; Janice S Lee; Susan Y Euling
Journal:  Mamm Genome       Date:  2018-02-23       Impact factor: 3.224
  2 in total

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