Literature DB >> 29080968

Sex selection for non-medical indications: a survey of current pre-implantation genetic screening practices among U.S. ART clinics.

Sarah M Capelouto1, Sydney R Archer2, Jerrine R Morris3, Jennifer F Kawwass4, Heather S Hipp4.   

Abstract

PURPOSE: This study aimed to determine the current percentage of United States (U.S.) assisted reproductive technology (ART) clinics offering sex selection via pre-implantation genetic screening (PGS) for non-medical purposes.
METHODS: The authors conducted website review and telephone interview survey of 493 U.S. ART clinics performing in vitro fertilization (IVF) in 2017. Main outcome measures were pre-implantation genetic screening (PGS)/pre-implantation genetic diagnosis (PGD) practices and non-medical sex selection practices including family balancing.
RESULTS: Of the 493 ART clinics in the USA, 482 clinics (97.8%) responded to our telephone interview survey. Among all U.S. ART clinics, 91.9% (n = 449) reported offering PGS and/or PGD. Furthermore, 476 clinics responded to survey questions about sex selection practices. Of those ART clinics, 72.7% (n = 346) reported offering sex selection. More specifically among those clinics offering sex selection, 93.6% (n = 324) reported performing sex selection for family balancing, and 81.2% (n = 281) reported performing for elective purposes (patient preference, regardless of rationale for the request). For couples without infertility, 83.5% (n = 289) of clinics offer sex selection for family balancing and 74.6% (n = 258) for non-specific elective reasons.
CONCLUSIONS: The majority of U.S. ART clinics offer non-medical sex selection, a percentage that has increased substantially since last reported in 2006.

Entities:  

Keywords:  Family balancing; Gender selection; Non-medical sex selection; Pre-implantation genetic diagnosis (PGD); Pre-implantation genetic screening (PGS)

Mesh:

Year:  2017        PMID: 29080968      PMCID: PMC5904054          DOI: 10.1007/s10815-017-1076-2

Source DB:  PubMed          Journal:  J Assist Reprod Genet        ISSN: 1058-0468            Impact factor:   3.412


  5 in total

1.  Use of reproductive technology for sex selection for nonmedical reasons.

Authors: 
Journal:  Fertil Steril       Date:  2015-05-05       Impact factor: 7.329

2.  In vitro fertilization with preimplantation genetic screening.

Authors:  Sebastiaan Mastenbroek; Moniek Twisk; Jannie van Echten-Arends; Birgit Sikkema-Raddatz; Johanna C Korevaar; Harold R Verhoeve; Niels E A Vogel; Eus G J M Arts; Jan W A de Vries; Patrick M Bossuyt; Charles H C M Buys; Maas Jan Heineman; Sjoerd Repping; Fulco van der Veen
Journal:  N Engl J Med       Date:  2007-07-04       Impact factor: 91.245

3.  Comprehensive embryo testing. Experts' opinions regarding future directions: an expert panel study on comprehensive embryo testing.

Authors:  Kristien Hens; Wybo J Dondorp; Joep P M Geraedts; Guido M de Wert
Journal:  Hum Reprod       Date:  2013-02-15       Impact factor: 6.918

4.  ACOG Committee Opinion No. 360: Sex selection.

Authors: 
Journal:  Obstet Gynecol       Date:  2007-02       Impact factor: 7.661

5.  Genetic testing of embryos: practices and perspectives of US in vitro fertilization clinics.

Authors:  Susannah Baruch; David Kaufman; Kathy L Hudson
Journal:  Fertil Steril       Date:  2007-07-12       Impact factor: 7.329

  5 in total
  10 in total

Review 1.  Transitioning from Infertility-Based (ART 1.0) to Elective (ART 2.0) Use of Assisted Reproductive Technologies and the DOHaD Hypothesis: Do We Need to Change Consenting?

Authors:  Paolo Rinaudo; Amanda Adeleye
Journal:  Semin Reprod Med       Date:  2019-03-13       Impact factor: 1.303

2.  Perceptions towards sex selection among Jordanian population: A survey study.

Authors:  Saleem Ali Banihani; Karem H Alzoubi; Mohammad S Shawaqfeh; Senthilvel Vasudevan
Journal:  Andrologia       Date:  2022-06-20       Impact factor: 2.532

3.  Evaluating standards for 'serious' disease for preimplantation genetic testing: a multi-case study on regulatory frameworks in Japan, the UK, and Western Australia.

Authors:  Kate Nakasato; Beverley Anne Yamamoto; Kazuto Kato
Journal:  Hum Genomics       Date:  2022-05-18       Impact factor: 6.481

4.  Pre-implantation genetic testing alters the sex ratio: an analysis of 91,805 embryo transfer cycles.

Authors:  Kathryn Shaia; Tracy Truong; Carl Pieper; Anne Steiner
Journal:  J Assist Reprod Genet       Date:  2020-03-25       Impact factor: 3.412

Review 5.  Regulating Preimplantation Genetic Testing across the World: A Comparison of International Policy and Ethical Perspectives.

Authors:  Margaret E C Ginoza; Rosario Isasi
Journal:  Cold Spring Harb Perspect Med       Date:  2020-05-01       Impact factor: 6.915

Review 6.  Cross border reproductive care (CBRC): a growing global phenomenon with multidimensional implications (a systematic and critical review).

Authors:  Mahmoud Salama; Vladimir Isachenko; Evgenia Isachenko; Gohar Rahimi; Peter Mallmann; Lynn M Westphal; Marcia C Inhorn; Pasquale Patrizio
Journal:  J Assist Reprod Genet       Date:  2018-05-28       Impact factor: 3.412

7.  Embryo quality, ploidy, and transfer outcomes in male versus female blastocysts.

Authors:  Christopher P Moutos; William G Kearns; Sarah E Farmer; Jon P Richards; Antonio F Saad; John R Crochet
Journal:  J Assist Reprod Genet       Date:  2021-06-04       Impact factor: 3.357

8.  The effect of religious background on the attitude towards sex selection.

Authors:  Anastasia A Salame; Jospeh Nassif; Ghina S Ghazeeri; Elie M Moubarak; Antoine Hannoun; Antoine A Abu Musa
Journal:  Eur J Obstet Gynecol Reprod Biol X       Date:  2019-05-17

9.  Disparities among infertility patients regarding genetic carrier screening, sex selection, and gene editing.

Authors:  Dana B McQueen; Christopher M Warren; Alexander H Xiao; Lee P Shulman; Tarun Jain
Journal:  J Assist Reprod Genet       Date:  2021-06-25       Impact factor: 3.357

Review 10.  Sex selection and non-invasive prenatal testing: A review of current practices, evidence, and ethical issues.

Authors:  Hilary Bowman-Smart; Julian Savulescu; Christopher Gyngell; Cara Mand; Martin B Delatycki
Journal:  Prenat Diagn       Date:  2019-10-10       Impact factor: 3.050

  10 in total

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