Literature DB >> 2895189

Absence of close linkage between benign hereditary chorea and the locus D4S10 (probe G8).

O W Quarrell1, S Youngman, M Sarfarazi, P S Harper.   

Abstract

A genetic linkage study between benign hereditary chorea and the locus D4S10 using the DNA probe G8 has shown two recombinations in five small families. There were negative lod scores at recombination fractions that show conclusive evidence of linkage in 16 larger British Huntington's disease families. We suggest that although benign hereditary chorea and Huntington's disease may have some clinical similarities they are probably at two different loci.

Entities:  

Mesh：

Year:  1988        PMID： 2895189      PMCID： PMC1015485          DOI： 10.1136/jmg.25.3.191

Source DB:  PubMed          Journal:  J Med Genet        ISSN： 0022-2593            Impact factor:   6.318


  13 in total

1.  Benign hereditary non-progressive chorea of early onset. Clinical genetics of the syndrome and report of a new family.

Authors:  J Burns; G Neuhäuser; L Tomasi
Journal:  Neuropadiatrie       Date:  1976-11

2.  Genetic linkage between Huntington's disease and the DNA polymorphism G8 in South Wales families.

Authors:  P S Harper; S Youngman; M A Anderson; M Sarfarazi; O Quarrell; R Tanzi; D Shaw; P Wallace; P M Conneally; J F Gusella
Journal:  J Med Genet       Date:  1985-12       Impact factor: 6.318

3.  Studies of a DNA marker (G8) genetically linked to Huntington disease in British families.

Authors:  S Youngman; M Sarfarazi; O W Quarrell; P M Conneally; K Gibbons; P S Harper; D J Shaw; R E Tanzi; M R Wallace; J F Gusella
Journal:  Hum Genet       Date:  1986-08       Impact factor: 4.132

4.  Familial benign chorea with intention tremor: a clinical entity.

Authors:  J H Pincus; A Chutorian
Journal:  J Pediatr       Date:  1967-05       Impact factor: 4.406

5.  A polymorphic DNA marker genetically linked to Huntington's disease.

Authors:  J F Gusella; N S Wexler; P M Conneally; S L Naylor; M A Anderson; R E Tanzi; P C Watkins; K Ottina; M R Wallace; A Y Sakaguchi
Journal:  Nature       Date:  1983 Nov 17-23       Impact factor: 49.962

6.  Localisation of the Becker muscular dystrophy gene on the short arm of the X chromosome by linkage to cloned DNA sequences.

Authors:  H M Kingston; M Sarfarazi; N S Thomas; P S Harper
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

7.  Strategies for multilocus linkage analysis in humans.

Authors:  G M Lathrop; J M Lalouel; C Julier; J Ott
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

8.  Benign familial chorea: an association with intellectual impairment.

Authors:  D A Leli; T W Furlow; J C Falgout
Journal:  J Neurol Neurosurg Psychiatry       Date:  1984-05       Impact factor: 10.154

9.  Huntington's disease: two families with differing clinical features show linkage to the G8 probe.

Authors:  S E Folstein; J A Phillips; D A Meyers; G A Chase; M H Abbott; M L Franz; P G Waber; H H Kazazian; P M Conneally; W Hobbs
Journal:  Science       Date:  1985-08-23       Impact factor: 47.728

10.  Deletion of Huntington's disease-linked G8 (D4S10) locus in Wolf-Hirschhorn syndrome.

Authors:  J F Gusella; R E Tanzi; P I Bader; M C Phelan; R Stevenson; M R Hayden; K J Hofman; A G Faryniarz; K Gibbons
Journal:  Nature       Date:  1985 Nov 7-13       Impact factor: 49.962
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  4 in total

1.  Benign hereditary chorea of early onset maps to chromosome 14q.

Authors:  B B de Vries; W F Arts; G J Breedveld; J J Hoogeboom; M F Niermeijer; P Heutink
Journal:  Am J Hum Genet       Date:  2000-01       Impact factor: 11.025

Review 2.  A specific mutation for Huntington's disease.

Authors:  P S Harper
Journal:  J Med Genet       Date:  1993-12       Impact factor: 6.318

3.  Identification of an expanded CAG repeat in the Huntington's disease gene (IT15) in a family reported to have benign hereditary chorea.

Authors:  J C MacMillan; P J Morrison; N C Nevin; D J Shaw; P S Harper; O W Quarrell; R G Snell
Journal:  J Med Genet       Date:  1993-12       Impact factor: 6.318

4.  The epidemiology of Huntington's disease in Northern Ireland.

Authors:  P J Morrison; W P Johnston; N C Nevin
Journal:  J Med Genet       Date:  1995-07       Impact factor: 6.318
  4 in total

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