Literature DB >> 6316146

A polymorphic DNA marker genetically linked to Huntington's disease.

J F Gusella, N S Wexler, P M Conneally, S L Naylor, M A Anderson, R E Tanzi, P C Watkins, K Ottina, M R Wallace, A Y Sakaguchi.   

Abstract

Family studies show that the Huntington's disease gene is linked to a polymorphic DNA marker that maps to human chromosome 4. The chromosomal localization of the Huntington's disease gene is the first step in using recombinant DNA technology to identify the primary genetic defect in this disorder.

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Year:  1983        PMID： 6316146     DOI： 10.1038/306234a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  467 in total

1.  Huntington's disease: a clinical, genetic and molecular model for polyglutamine repeat disorders.

Authors:  P S Harper
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1999-06-29       Impact factor: 6.237

2.  Bayesian fine-scale mapping of disease loci, by hidden Markov models.

Authors:  A P Morris; J C Whittaker; D J Balding
Journal:  Am J Hum Genet       Date:  2000-06-01       Impact factor: 11.025

3.  A coalescent approach to study linkage disequilibrium between single-nucleotide polymorphisms.

Authors:  S Zöllner; A von Haeseler
Journal:  Am J Hum Genet       Date:  2000-02       Impact factor: 11.025

Review 4.  Psychological impact of genetic testing for Huntington's disease: an update of the literature.

Authors:  B Meiser; S Dunn
Journal:  J Neurol Neurosurg Psychiatry       Date:  2000-11       Impact factor: 10.154

Review 5.  Huntington's disease.

Authors:  S Davies; D B Ramsden
Journal:  Mol Pathol       Date:  2001-12

6.  A perspective on epistasis: limits of models displaying no main effect.

Authors:  Robert Culverhouse; Brian K Suarez; Jennifer Lin; Theodore Reich
Journal:  Am J Hum Genet       Date:  2002-01-08       Impact factor: 11.025

Review 7.  Psychological effect of genetic testing for Huntington's disease: an update of the literature.

Authors:  B Meiser; S Dunn
Journal:  West J Med       Date:  2001-05

8.  Predictive testing for Huntington's disease: ten years' experience in two Italian centres.

Authors:  P Mandich; G Jacopini; E Di Maria; G Sabbadini; G Abbruzzese; F Chimirri; E Bellone; A Novelletto; F Ajmar; M Frontali
Journal:  Ital J Neurol Sci       Date:  1998-04

9.  Intelligence indices in people with a high/low risk for developing Huntington's disease.

Authors:  G M de Boo; A Tibben; J B Lanser; A Jennekens-Schinkel; J Hermans; M Vegter-van der Vlis; R A Roos
Journal:  J Med Genet       Date:  1997-07       Impact factor: 6.318

10.  The Huntington disease locus is most likely within 325 kilobases of the chromosome 4p telomere.

Authors:  N A Doggett; J F Cheng; C L Smith; C R Cantor
Journal:  Proc Natl Acad Sci U S A       Date:  1989-12       Impact factor: 11.205
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