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Literature DB >> 28827223

Long Noncoding RNA Facilitated Gene Therapy Reduces Atherosclerosis in a Murine Model of Familial Hypercholesterolemia.

Peter Tontonoz¹, Xiaohui Wu¹, Marius Jones¹, Zhengyi Zhang¹, David Salisbury¹, Tamer Sallam².

Abstract

Entities: Chemical

Keywords: RNA, long noncoding; atherosclerosis; cholesterol; genetic therapy

Mesh：

Substances：

Year: 2017 PMID： 28827223 PMCID： PMC5657526 DOI： 10.1161/CIRCULATIONAHA.117.029002

Source DB: PubMed Journal: Circulation ISSN： 0009-7322 Impact factor: 29.690

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5 in total

Review 1. Unique features of long non-coding RNA biogenesis and function.

Authors: Jeffrey J Quinn; Howard Y Chang
Journal: Nat Rev Genet Date: 2016-01 Impact factor: 53.242

2. Lipid-lowering treatment for homozygous familial hypercholesterolaemia--authors' reply.

Authors: Marina Cuchel; Daniel J Rader
Journal: Lancet Date: 2013-04-06 Impact factor: 79.321

3. Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis.

Authors: Katey J Rayner; Frederick J Sheedy; Christine C Esau; Farah N Hussain; Ryan E Temel; Saj Parathath; Janine M van Gils; Alistair J Rayner; Aaron N Chang; Yajaira Suarez; Carlos Fernandez-Hernando; Edward A Fisher; Kathryn J Moore
Journal: J Clin Invest Date: 2011-06-06 Impact factor: 14.808

4. Treatment Gaps in Adults With Heterozygous Familial Hypercholesterolemia in the United States: Data From the CASCADE-FH Registry.

Authors: Emil M deGoma; Zahid S Ahmad; Emily C O'Brien; Iris Kindt; Peter Shrader; Connie B Newman; Yashashwi Pokharel; Seth J Baum; Linda C Hemphill; Lisa C Hudgins; Catherine D Ahmed; Samuel S Gidding; Danielle Duffy; William Neal; Katherine Wilemon; Matthew T Roe; Daniel J Rader; Christie M Ballantyne; MacRae F Linton; P Barton Duell; Michael D Shapiro; Patrick M Moriarty; Joshua W Knowles
Journal: Circ Cardiovasc Genet Date: 2016-03-24

5. Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis.

Authors: Tamer Sallam; Marius C Jones; Thomas Gilliland; Li Zhang; Xiaohui Wu; Ascia Eskin; Jaspreet Sandhu; David Casero; Thomas Q de Aguiar Vallim; Cynthia Hong; Melanie Katz; Richard Lee; Julian Whitelegge; Peter Tontonoz
Journal: Nature Date: 2016-05-11 Impact factor: 49.962

5 in total

22 in total

1. Targeting epigenetics and non-coding RNAs in atherosclerosis: from mechanisms to therapeutics.

Authors: Suowen Xu; Danielle Kamato; Peter J Little; Shinichi Nakagawa; Jaroslav Pelisek; Zheng Gen Jin
Journal: Pharmacol Ther Date: 2018-11-13 Impact factor: 12.310

Review 2. LncRNAs in vascular biology and disease.

Authors: Viorel Simion; Stefan Haemmig; Mark W Feinberg
Journal: Vascul Pharmacol Date: 2018-02-06 Impact factor: 5.773

Review 3. Long intergenic noncoding RNAs in cardiovascular diseases: Challenges and strategies for physiological studies and translation.

Authors: Xuan Zhang; Daniel Y Li; Muredach P Reilly
Journal: Atherosclerosis Date: 2018-09-29 Impact factor: 5.162

Review 10. Decoding LncRNAs.

Authors: Lidia Borkiewicz; Joanna Kalafut; Karolina Dudziak; Alicja Przybyszewska-Podstawka; Ilona Telejko
Journal: Cancers (Basel) Date: 2021-05-27 Impact factor: 6.639

Long Noncoding RNA Facilitated Gene Therapy Reduces Atherosclerosis in a Murine Model of Familial Hypercholesterolemia.

Review 1. Unique features of long non-coding RNA biogenesis and function.

2. Lipid-lowering treatment for homozygous familial hypercholesterolaemia--authors' reply.

3. Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis.

4. Treatment Gaps in Adults With Heterozygous Familial Hypercholesterolemia in the United States: Data From the CASCADE-FH Registry.

5. Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis.

1. Targeting epigenetics and non-coding RNAs in atherosclerosis: from mechanisms to therapeutics.

Review 2. LncRNAs in vascular biology and disease.

Review 3. Long intergenic noncoding RNAs in cardiovascular diseases: Challenges and strategies for physiological studies and translation.

Review 4. Genetics-driven discovery of novel regulators of lipid metabolism.

5. Hypothalamic long noncoding RNA AK044061 is involved in the development of dietary obesity in mice.

Review 6. Long noncoding RNAs in lipid metabolism.

Review 7. Long Noncoding RNAs in Atherosclerosis and Vascular Injury: Pathobiology, Biomarkers, and Targets for Therapy.

Review 8. Long Noncoding RNAs in Atherosclerosis: JACC Review Topic of the Week.

Review 9. Regulation of Long Non-Coding RNAs by Statins in Atherosclerosis.

Review 10. Decoding LncRNAs.