Humberto Fernández-Olarte1,2, Andrés Gómez-Delgado3,4,5, Dayan López-Dávila6, Rodolfo Rangel-Perdomo6, Gloria Inés Lafaurie7,8, Leandro Chambrone7,9. 1. Oral and Maxillofacial Surgery Residency Program, Universidad El Bosque, Bogotá, Colombia. 2. Department of Oral and Maxillofacial Surgery, Clínica El Bosque and Hospital Simón Bolívar, Bogotá, Colombia. 3. Universidad El Bosque, Bogotá, Colombia. 4. Private Practice, San José, Costa Rica. 5. Departamento de Cirugía Oral y Maxilofacial, Universidad El Bosque, Carrera 7 B Bis No. 132-11, Bogotá, Código Postal 110121 Colombia. 6. Department of Oral and Maxillofacial Surgery, Universidad El Bosque, Bogotá, Colombia. 7. Unit of Basic Oral Investigations (UIBO), School of Dentistry, Universidad El Bosque, Bogotá, Colombia. 8. Department of Periodontics, School of Dentistry, Universidad El Bosque, Bogotá, Colombia. 9. Department of Periodontics, College of Dentisty, The University of Iowa, Iowa City, IA USA.
Abstract
PURPOSE: The purpose of this systematic review was to evaluate, in animal model-based studies, whether there are mandibular growth alterations, after open reduction and internal rigid fixation with titanium plates and screws. METHODS: A literature search was conducted using the MEDLINE, EMBASE, and LILACS databases, up to and including August 2015. Surgical reduction and internal rigid fixation (IRF) of induced fractures were compared to non-invasive procedures, in order to investigate if there were alterations in the mandibular growth patterns. RESULTS: Of a total of 624 potentially relevant papers identified through the searching process, five were eligible for inclusion. Three studies using 3-month old New Zealand white rabbits induced fractures of mandibular body or symphysis and internal fixation with titanium microplates and screws, whereas two were based on 6-month old goats with condylar fracture. None of the studies showed statistically significant difference between experimental and control groups. CONCLUSION: As literature regarding this subject is scarce, and the included studies show low level of evidence, it is not possible to conclude that open reduction and internal rigid fixation with titanium plates and screws cause significant growing alteration of the mandible.
PURPOSE: The purpose of this systematic review was to evaluate, in animal model-based studies, whether there are mandibular growth alterations, after open reduction and internal rigid fixation with titanium plates and screws. METHODS: A literature search was conducted using the MEDLINE, EMBASE, and LILACS databases, up to and including August 2015. Surgical reduction and internal rigid fixation (IRF) of induced fractures were compared to non-invasive procedures, in order to investigate if there were alterations in the mandibular growth patterns. RESULTS: Of a total of 624 potentially relevant papers identified through the searching process, five were eligible for inclusion. Three studies using 3-month old New Zealand white rabbits induced fractures of mandibular body or symphysis and internal fixation with titanium microplates and screws, whereas two were based on 6-month old goats with condylar fracture. None of the studies showed statistically significant difference between experimental and control groups. CONCLUSION: As literature regarding this subject is scarce, and the included studies show low level of evidence, it is not possible to conclude that open reduction and internal rigid fixation with titanium plates and screws cause significant growing alteration of the mandible.
Entities:
Keywords:
Animal model; Internal fixation; Mandibular growth; Open reduction
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