Literature DB >> 27826610

Identification of Long Bone Fractures in Radiology Reports Using Natural Language Processing to support Healthcare Quality Improvement.

Robert W Grundmeier1, Aaron J Masino, T Charles Casper, Jonathan M Dean, Jamie Bell, Rene Enriquez, Sara Deakyne, James M Chamberlain, Elizabeth R Alpern.   

Abstract

BACKGROUND: Important information to support healthcare quality improvement is often recorded in free text documents such as radiology reports. Natural language processing (NLP) methods may help extract this information, but these methods have rarely been applied outside the research laboratories where they were developed.
OBJECTIVE: To implement and validate NLP tools to identify long bone fractures for pediatric emergency medicine quality improvement.
METHODS: Using freely available statistical software packages, we implemented NLP methods to identify long bone fractures from radiology reports. A sample of 1,000 radiology reports was used to construct three candidate classification models. A test set of 500 reports was used to validate the model performance. Blinded manual review of radiology reports by two independent physicians provided the reference standard. Each radiology report was segmented and word stem and bigram features were constructed. Common English "stop words" and rare features were excluded. We used 10-fold cross-validation to select optimal configuration parameters for each model. Accuracy, recall, precision and the F1 score were calculated. The final model was compared to the use of diagnosis codes for the identification of patients with long bone fractures.
RESULTS: There were 329 unique word stems and 344 bigrams in the training documents. A support vector machine classifier with Gaussian kernel performed best on the test set with accuracy=0.958, recall=0.969, precision=0.940, and F1 score=0.954. Optimal parameters for this model were cost=4 and gamma=0.005. The three classification models that we tested all performed better than diagnosis codes in terms of accuracy, precision, and F1 score (diagnosis code accuracy=0.932, recall=0.960, precision=0.896, and F1 score=0.927).
CONCLUSIONS: NLP methods using a corpus of 1,000 training documents accurately identified acute long bone fractures from radiology reports. Strategic use of straightforward NLP methods, implemented with freely available software, offers quality improvement teams new opportunities to extract information from narrative documents.

Entities:  

Keywords:  Natural language processing; emergency medicine; machine learning; pediatrics; quality improvement

Mesh:

Year:  2016        PMID: 27826610      PMCID: PMC5228143          DOI: 10.4338/ACI-2016-08-RA-0129

Source DB:  PubMed          Journal:  Appl Clin Inform        ISSN: 1869-0327            Impact factor:   2.342


  22 in total

1.  PhysioBank, PhysioToolkit, and PhysioNet: components of a new research resource for complex physiologic signals.

Authors:  A L Goldberger; L A Amaral; L Glass; J M Hausdorff; P C Ivanov; R G Mark; J E Mietus; G B Moody; C K Peng; H E Stanley
Journal:  Circulation       Date:  2000-06-13       Impact factor: 29.690

2.  Evaluation of biomedical text-mining systems: lessons learned from information retrieval.

Authors:  William Hersh
Journal:  Brief Bioinform       Date:  2005-12       Impact factor: 11.622

Review 3.  Natural language processing: an introduction.

Authors:  Prakash M Nadkarni; Lucila Ohno-Machado; Wendy W Chapman
Journal:  J Am Med Inform Assoc       Date:  2011 Sep-Oct       Impact factor: 4.497

4.  Information extraction from multi-institutional radiology reports.

Authors:  Saeed Hassanpour; Curtis P Langlotz
Journal:  Artif Intell Med       Date:  2015-10-03       Impact factor: 5.326

5.  Regularization Paths for Generalized Linear Models via Coordinate Descent.

Authors:  Jerome Friedman; Trevor Hastie; Rob Tibshirani
Journal:  J Stat Softw       Date:  2010       Impact factor: 6.440

6.  A comparison of two approaches to text processing: facilitating chart reviews of radiology reports in electronic medical records.

Authors:  Julie A Womack; Matthew Scotch; Cynthia Gibert; Wendy Chapman; Michael Yin; Amy C Justice; Cynthia Brandt
Journal:  Perspect Health Inf Manag       Date:  2010-10-01

7.  Normalization and standardization of electronic health records for high-throughput phenotyping: the SHARPn consortium.

Authors:  Jyotishman Pathak; Kent R Bailey; Calvin E Beebe; Steven Bethard; David C Carrell; Pei J Chen; Dmitriy Dligach; Cory M Endle; Lacey A Hart; Peter J Haug; Stanley M Huff; Vinod C Kaggal; Dingcheng Li; Hongfang Liu; Kyle Marchant; James Masanz; Timothy Miller; Thomas A Oniki; Martha Palmer; Kevin J Peterson; Susan Rea; Guergana K Savova; Craig R Stancl; Sunghwan Sohn; Harold R Solbrig; Dale B Suesse; Cui Tao; David P Taylor; Les Westberg; Stephen Wu; Ning Zhuo; Christopher G Chute
Journal:  J Am Med Inform Assoc       Date:  2013-11-04       Impact factor: 4.497

8.  Caveats for the use of operational electronic health record data in comparative effectiveness research.

Authors:  William R Hersh; Mark G Weiner; Peter J Embi; Judith R Logan; Philip R O Payne; Elmer V Bernstam; Harold P Lehmann; George Hripcsak; Timothy H Hartzog; James J Cimino; Joel H Saltz
Journal:  Med Care       Date:  2013-08       Impact factor: 2.983

9.  Automated outcome classification of emergency department computed tomography imaging reports.

Authors:  Kabir Yadav; Efsun Sarioglu; Meaghan Smith; Hyeong-Ah Choi
Journal:  Acad Emerg Med       Date:  2013-08       Impact factor: 3.451

Review 10.  The impact of eHealth on the quality and safety of health care: a systematic overview.

Authors:  Ashly D Black; Josip Car; Claudia Pagliari; Chantelle Anandan; Kathrin Cresswell; Tomislav Bokun; Brian McKinstry; Rob Procter; Azeem Majeed; Aziz Sheikh
Journal:  PLoS Med       Date:  2011-01-18       Impact factor: 11.069

View more
  14 in total

1.  The Pediatric Emergency Care Applied Research Network Registry: A Multicenter Electronic Health Record Registry of Pediatric Emergency Care.

Authors:  Sara J Deakyne Davies; Robert W Grundmeier; Diego A Campos; Katie L Hayes; Jamie Bell; Evaline A Alessandrini; Lalit Bajaj; James M Chamberlain; Marc H Gorelick; Rene Enriquez; T Charles Casper; Beth Scheid; Marlena Kittick; J Michael Dean; Elizabeth R Alpern
Journal:  Appl Clin Inform       Date:  2018-05-23       Impact factor: 2.342

2.  Opioid Prescription Patterns at Emergency Department Discharge for Children with Fractures.

Authors:  Amy L Drendel; David C Brousseau; T Charles Casper; Lalit Bajaj; Evaline A Alessandrini; Robert W Grundmeier; James M Chamberlain; Monika K Goyal; Cody S Olsen; Elizabeth R Alpern
Journal:  Pain Med       Date:  2020-09-01       Impact factor: 3.750

3.  Interactive NLP in Clinical Care: Identifying Incidental Findings in Radiology Reports.

Authors:  Gaurav Trivedi; Esmaeel R Dadashzadeh; Robert M Handzel; Wendy W Chapman; Shyam Visweswaran; Harry Hochheiser
Journal:  Appl Clin Inform       Date:  2019-09-04       Impact factor: 2.342

Review 4.  Making Sense of Big Textual Data for Health Care: Findings from the Section on Clinical Natural Language Processing.

Authors:  A Névéol; P Zweigenbaum
Journal:  Yearb Med Inform       Date:  2017-09-11

Review 5.  "Minimally invasive research?" Use of the electronic health record to facilitate research in pediatric urology.

Authors:  Vijaya M Vemulakonda; Ruth A Bush; Michael G Kahn
Journal:  J Pediatr Urol       Date:  2018-06-09       Impact factor: 1.830

6.  Racial and Ethnic Differences in Emergency Department Pain Management of Children With Fractures.

Authors:  Monika K Goyal; Tiffani J Johnson; James M Chamberlain; Lawrence Cook; Michael Webb; Amy L Drendel; Evaline Alessandrini; Lalit Bajaj; Scott Lorch; Robert W Grundmeier; Elizabeth R Alpern
Journal:  Pediatrics       Date:  2020-04-20       Impact factor: 7.124

7.  Machine Learning for Detection of Correct Peripherally Inserted Central Catheter Tip Position from Radiology Reports in Infants.

Authors:  Manan Shah; Derek Shu; V B Surya Prasath; Yizhao Ni; Andrew H Schapiro; Kevin R Dufendach
Journal:  Appl Clin Inform       Date:  2021-09-08       Impact factor: 2.762

8.  A Web Application for Adrenal Incidentaloma Identification, Tracking, and Management Using Machine Learning.

Authors:  Wasif Bala; Jackson Steinkamp; Timothy Feeney; Avneesh Gupta; Abhinav Sharma; Jake Kantrowitz; Nicholas Cordella; James Moses; Frederick Thurston Drake
Journal:  Appl Clin Inform       Date:  2020-09-16       Impact factor: 2.342

9.  Natural language processing of radiology reports for the identification of patients with fracture.

Authors:  Nithin Kolanu; A Shane Brown; Amanda Beech; Jacqueline R Center; Christopher P White
Journal:  Arch Osteoporos       Date:  2021-01-06       Impact factor: 2.617

10.  Natural language processing of radiology reports for identification of skeletal site-specific fractures.

Authors:  Yanshan Wang; Saeed Mehrabi; Sunghwan Sohn; Elizabeth J Atkinson; Shreyasee Amin; Hongfang Liu
Journal:  BMC Med Inform Decis Mak       Date:  2019-04-04       Impact factor: 2.796

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.