Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Influence of two quinolones, ofloxacin and pefloxacin, on human myelopoiesis in vitro.

Literature DB >> 2712545

Influence of two quinolones, ofloxacin and pefloxacin, on human myelopoiesis in vitro.

F Pallavicini¹, A Antinori, G Federico, M Fantoni, P Nervo.

Abstract

The influence of ofloxacin and pefloxacin on human myelopoiesis in vitro was investigated. Drug concentrations varied from 0.5 to 50 micrograms/ml, and the effect on granulomonocyte precursors was evaluated on cell cultures in agar. Our results indicate that ofloxacin and pefloxacin do not induce inhibition of myelopoiesis.

Entities: Chemical Species

Mesh：

Substances：
Pefloxacin
Ofloxacin

Year: 1989 PMID： 2712545 PMCID： PMC171436 DOI： 10.1128/AAC.33.1.122

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

18 in total

1. Aryl-fluoroquinolone derivatives A-56619 (difloxacin) and A-56620 inhibit mitogen-induced human mononuclear cell proliferation.

Authors: S V Gollapudi; B Vayuvegula; S Gupta; M Fok; H Thadepalli
Journal: Antimicrob Agents Chemother Date: 1986-09 Impact factor: 5.191

2. Influence of ofloxacin, norfloxacin, nalidixic acid, pyromidic acid and pipemidic acid on human gamma-interferon production and blastogenesis.

Authors: C De Simone; L Baldinelli; M Ferrazzi; S De Santis; L Pugnaloni; F Sorice
Journal: J Antimicrob Chemother Date: 1986-06 Impact factor: 5.790

3. Influence of ofloxacin and pefloxacin on human lymphocyte immunoglobulin secretion and on polymorphonuclear leucocyte superoxide anion production.

Authors: M Fantoni; E Tamburrini; F Pallavicini; A Antinori; P Nervo
Journal: J Antimicrob Chemother Date: 1988-08 Impact factor: 5.790

4. The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro.

Authors: J S Wolfson; D C Hooper
Journal: Antimicrob Agents Chemother Date: 1985-10 Impact factor: 5.191

5. Human bone marrow colony growth in agar-gel.

Authors: B L Pike; W A Robinson
Journal: J Cell Physiol Date: 1970-08 Impact factor: 6.384

6. Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase alpha primase complex, topoisomerases I and II, and growth of mammalian lymphoblasts.

Authors: P Hussy; G Maass; B Tümmler; F Grosse; U Schomburg
Journal: Antimicrob Agents Chemother Date: 1986-06 Impact factor: 5.191

Influence of two quinolones, ofloxacin and pefloxacin, on human myelopoiesis in vitro.

1. Aryl-fluoroquinolone derivatives A-56619 (difloxacin) and A-56620 inhibit mitogen-induced human mononuclear cell proliferation.

2. Influence of ofloxacin, norfloxacin, nalidixic acid, pyromidic acid and pipemidic acid on human gamma-interferon production and blastogenesis.

3. Influence of ofloxacin and pefloxacin on human lymphocyte immunoglobulin secretion and on polymorphonuclear leucocyte superoxide anion production.

4. The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro.

5. Human bone marrow colony growth in agar-gel.

6. Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase alpha primase complex, topoisomerases I and II, and growth of mammalian lymphoblasts.

7. Effects of ciprofloxacin on the humoral and cellular immune responses in Balb/c-mice.

8. Effect of ciprofloxacin on phagocytosis.

9. Quinolones affect thymidine incorporation into the DNA of human lymphocytes.

10. Effect of ciprofloxacin on mitogen-stimulated lymphocyte proliferation.

Review 1. Immunological aspects of new quinolones.

2. Inhibitory effects of quinolones on DNA gyrase of Escherichia coli and topoisomerase II of fetal calf thymus.

Review 3. Pefloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

4. Modification of immune response in mice by ciprofloxacin.