Literature DB >> 3090010

Influence of ofloxacin, norfloxacin, nalidixic acid, pyromidic acid and pipemidic acid on human gamma-interferon production and blastogenesis.

C De Simone, L Baldinelli, M Ferrazzi, S De Santis, L Pugnaloni, F Sorice.   

Abstract

Several new quinolone derivatives were investigated for their influence on human lymphocyte blastogenesis and gamma-interferon production following concanavalin A stimulation. All the antimicrobials induced inhibition of lymphocyte DNA synthesis. The gamma-interferon measurements showed that nalidixic acid and norfloxacin have a negative influence on lymphokine production and release.

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Year:  1986        PMID： 3090010     DOI： 10.1093/jac/17.6.811

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN： 0305-7453            Impact factor:   5.790


  9 in total

1.  Selective enhancement of synthesis of interleukin-2 in lymphocytes in the presence of ciprofloxacin.

Authors:  K Riesbeck; A Forsgren
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1990-06       Impact factor: 3.267

Review 2.  Immunological aspects of new quinolones.

Authors:  I Shalit
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1991-04       Impact factor: 3.267

3.  In vitro effect of ciprofloxacin on HT-29 human colon carcinoma cell line: assessment of cell proliferation by thymidine uptake and silver nucleolar organizer regions (AgNOR) histomorphometry.

Authors:  M Rabau; A Nyska; D Dayan
Journal:  Arch Toxicol       Date:  1995       Impact factor: 5.153

4.  Influence of two quinolones, ofloxacin and pefloxacin, on human myelopoiesis in vitro.

Authors:  F Pallavicini; A Antinori; G Federico; M Fantoni; P Nervo
Journal:  Antimicrob Agents Chemother       Date:  1989-01       Impact factor: 5.191

5.  Assessment of immunomodulating activity of ofloxacin and three other quinolones in human plasma.

Authors:  C De Simone; V Vullo; M Grassi; S Di Fabio; L Baldinelli; F Sorice
Journal:  Infection       Date:  1986       Impact factor: 3.553

Review 6.  Ofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  J P Monk; D M Campoli-Richards
Journal:  Drugs       Date:  1987-04       Impact factor: 9.546

7.  Effect of quinolones and other antimicrobial agents on cell-associated Legionella pneumophila.

Authors:  D Havlichek; L Saravolatz; D Pohlod
Journal:  Antimicrob Agents Chemother       Date:  1987-10       Impact factor: 5.191

8.  4-Quinolone drugs affect cell cycle progression and function of human lymphocytes in vitro.

Authors:  A Forsgren; S F Schlossman; T F Tedder
Journal:  Antimicrob Agents Chemother       Date:  1987-05       Impact factor: 5.191

9.  Prophylactic ciprofloxacin treatment prevented high mortality, and modified systemic and intestinal immune function in tumour-bearing rats receiving dose-intensive CPT-11 chemotherapy.

Authors:  H Xue; C J Field; M B Sawyer; L A Dieleman; V E Baracos
Journal:  Br J Cancer       Date:  2009-04-28       Impact factor: 7.640
  9 in total

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