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Literature DB >> 3717944

Quinolones affect thymidine incorporation into the DNA of human lymphocytes.

A Forsgren, A K Bergh, M Brandt, G Hansson.

Abstract

The incorporation of [3H]thymidine into DNA was increased in phytohemagglutinin-stimulated human lymphocytes exposed to four of the new quinolone derivatives (ciprofloxacin, norfloxacin, ofloxacin, and A 56620) at concentrations achievable in clinical situations. However, proliferation of phytohemagglutinin-stimulated lymphocytes was not influenced by ciprofloxacin at concentrations of 0.5 to 10 micrograms/ml.

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Year: 1986 PMID： 3717944 PMCID： PMC180422 DOI： 10.1128/AAC.29.3.506

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

12 in total

1. Many bacterial species are mitogenic for human blood B lymphocytes.

Authors: G Banck; A Forsgren
Journal: Scand J Immunol Date: 1978 Impact factor: 3.487

2. Antibiotics and suppression of lymphocyte function in vitro.

Authors: G Banck; A Forsgren
Journal: Antimicrob Agents Chemother Date: 1979-11 Impact factor: 5.191

3. Formation of bacteriolytic enzymes in batch and continuous culture of Staphylococcus aureus.

Authors: S Arvidson; T Holme; T Wadström
Journal: J Bacteriol Date: 1970-10 Impact factor: 3.490

4. Effect of doxycycline on immune response in mice.

Authors: A Bellahsene; A Forsgren
Journal: Infect Immun Date: 1985-05 Impact factor: 3.441

5. Effect of fusidic acid on the immune response in mice.

Authors: A Bellahsène; A Forsgren
Journal: Infect Immun Date: 1980-09 Impact factor: 3.441

6. Lymphocyte stimulation by protein A of Staphylococcus aureus.

Authors: A Forsgren; A Svedjelund; H Wigzell
Journal: Eur J Immunol Date: 1976-03 Impact factor: 5.532

7. The immune system of cyprinid fish. Oxytetracycline and the regulation of humoral immunity in carp (Cyprinus carpio).

Authors: G T Rijkers; R Van Oosterom; W B Van Muiswinkel
Journal: Vet Immunol Immunopathol Date: 1981-06 Impact factor: 2.046

8. Effect of tetracycline treatment on immunological responses in mice.

Authors: Y H Thong; A Ferrante
Journal: Clin Exp Immunol Date: 1980-03 Impact factor: 4.330

9. Comparative in vitro activity of three new quinolone antibiotics against recent clinical isolates.

Authors: A Forsgren
Journal: Scand J Infect Dis Date: 1985

10. Antibiotic-host defence interactions in vitro and in vivo.

Authors: A Forsgren; G Banck; H Beckman; A Bellahsène
Journal: Scand J Infect Dis Suppl Date: 1980

14 in total

1. Selective enhancement of synthesis of interleukin-2 in lymphocytes in the presence of ciprofloxacin.

Authors: K Riesbeck; A Forsgren
Journal: Eur J Clin Microbiol Infect Dis Date: 1990-06 Impact factor: 3.267

Review 2. Immunological aspects of new quinolones.

Authors: I Shalit
Journal: Eur J Clin Microbiol Infect Dis Date: 1991-04 Impact factor: 3.267

3. In vitro effect of ciprofloxacin on HT-29 human colon carcinoma cell line: assessment of cell proliferation by thymidine uptake and silver nucleolar organizer regions (AgNOR) histomorphometry.

Authors: M Rabau; A Nyska; D Dayan
Journal: Arch Toxicol Date: 1995 Impact factor: 5.153

9. Stimulation of DNA repair synthesis of rat thymocytes by novobiocin and nalidixic acid in vitro without detectable DNA damage.

Authors: K Tempel; A Spath
Journal: Arch Toxicol Date: 1987-06 Impact factor: 5.153

10. No cytogenetic effects of quinolone treatment in humans.

Authors: F Mitelman; A M Kolnig; B Strömbeck; R Norrby; B Kromann-Andersen; P Sommer; J Wadstein
Journal: Antimicrob Agents Chemother Date: 1988-06 Impact factor: 5.191