Literature DB >> 2940967

Effect of ciprofloxacin on mitogen-stimulated lymphocyte proliferation.

S V Gollapudi, R H Prabhala, H Thadepalli.   

Abstract

Ciprofloxacin was tested for its inhibitory or stimulatory effects on concanavalin A- and phytohemagglutinin-stimulated proliferation (measured by [3H]thymidine uptake) of human peripheral blood mononuclear cells and murine splenocytes. Ciprofloxacin did not diminish or enhance mononuclear cell proliferation at concentrations of 5 to 125 micrograms/ml. Further, the proliferative response of splenocytes of mice previously treated with ciprofloxacin (40 mg/kg, twice daily for 5 days) was essentially similar to that of untreated controls.

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Year:  1986        PMID： 2940967      PMCID： PMC176404          DOI： 10.1128/AAC.29.2.337

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

1.  Antibiotics and suppression of lymphocyte function in vitro.

Authors:  G Banck; A Forsgren
Journal:  Antimicrob Agents Chemother       Date:  1979-11       Impact factor: 5.191

2.  Simplified, accurate method for antibiotic assay of clinical specimens.

Authors:  J V Bennett; J L Brodie; E J Benner; W M Kirby
Journal:  Appl Microbiol       Date:  1966-03

3.  Suppression of lymphocyte responses by cephalosporins.

Authors:  E A Chaperon; W E Sanders
Journal:  Infect Immun       Date:  1978-02       Impact factor: 3.441

4.  Nonresponsiveness of immature B lymphocytes to anti-immunoglobulin is reversed by pronase.

Authors:  S V Gollapudi; M Ramanadham; M Kern
Journal:  Biochem Biophys Res Commun       Date:  1984-02-29       Impact factor: 3.575

Review 5.  Effect of antibiotics on the immune response.

Authors:  W E Hauser; J S Remington
Journal:  Am J Med       Date:  1982-05       Impact factor: 4.965

6.  Inhibition of mitogen-induced human lymphocyte proliferative responses by tetracycline analogues.

Authors:  Y H Thong; A Ferrante
Journal:  Clin Exp Immunol       Date:  1979-03       Impact factor: 4.330

7.  A novel mitogen released by lipid A-stimulated bone marrow cells.

Authors:  S V Gollapudi; M Kern
Journal:  J Immunol       Date:  1982-05       Impact factor: 5.422

8.  Quinolone antibiotics inhibit eucaryotic DNA polymerase alpha and beta, terminal deoxynucleotidyl transferase but not DNA ligase.

Authors:  R Rusquet; M Bonhommet; J C David
Journal:  Biochem Biophys Res Commun       Date:  1984-06-29       Impact factor: 3.575

9.  In vitro effects of doxycycline and tetracycline on mitogen stimulated lymphocyte growth.

Authors:  R C Potts; H A Hassan; R A Brown; A MacConnachie; J H Gibbs; A J Robertson; J S Beck
Journal:  Clin Exp Immunol       Date:  1983-08       Impact factor: 4.330

10.  Effects of moxalactam and cefuroxime on mitogen-stimulated human mononuclear leukocytes.

Authors:  J P Manzella; J K Clark
Journal:  Antimicrob Agents Chemother       Date:  1983-03       Impact factor: 5.191
  10 in total
  13 in total

1.  Selective enhancement of synthesis of interleukin-2 in lymphocytes in the presence of ciprofloxacin.

Authors:  K Riesbeck; A Forsgren
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1990-06       Impact factor: 3.267

2.  Aryl-fluoroquinolone derivatives A-56619 (difloxacin) and A-56620 inhibit mitogen-induced human mononuclear cell proliferation.

Authors:  S V Gollapudi; B Vayuvegula; S Gupta; M Fok; H Thadepalli
Journal:  Antimicrob Agents Chemother       Date:  1986-09       Impact factor: 5.191

Review 3.  Immunological aspects of new quinolones.

Authors:  I Shalit
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1991-04       Impact factor: 3.267

4.  In vitro effect of ciprofloxacin on HT-29 human colon carcinoma cell line: assessment of cell proliferation by thymidine uptake and silver nucleolar organizer regions (AgNOR) histomorphometry.

Authors:  M Rabau; A Nyska; D Dayan
Journal:  Arch Toxicol       Date:  1995       Impact factor: 5.153

5.  Influence of two quinolones, ofloxacin and pefloxacin, on human myelopoiesis in vitro.

Authors:  F Pallavicini; A Antinori; G Federico; M Fantoni; P Nervo
Journal:  Antimicrob Agents Chemother       Date:  1989-01       Impact factor: 5.191

Review 6.  Ciprofloxacin. A review of its pharmacological profile and therapeutic use in the elderly.

Authors:  L R Wiseman; J A Balfour
Journal:  Drugs Aging       Date:  1994-02       Impact factor: 3.923

Review 7.  Ciprofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  D M Campoli-Richards; J P Monk; A Price; P Benfield; P A Todd; A Ward
Journal:  Drugs       Date:  1988-04       Impact factor: 9.546

8.  Lack of in vitro antiviral activity of fluoroquinolones against herpes simplex virus type 2.

Authors:  A Pessina; E Mineo; L Gribaldo; M G Neri
Journal:  Arch Virol       Date:  1992       Impact factor: 2.574

9.  4-Quinolone drugs affect cell cycle progression and function of human lymphocytes in vitro.

Authors:  A Forsgren; S F Schlossman; T F Tedder
Journal:  Antimicrob Agents Chemother       Date:  1987-05       Impact factor: 5.191

10.  Effects of fluoroquinolones on the migration of human phagocytes through Chlamydia pneumoniae-infected and tumor necrosis factor alpha-stimulated endothelial cells.

Authors:  Silvia M Uriarte; Robert E Molestina; Richard D Miller; Jorge Bernabo; Alicia Farinati; Kumiko Eiguchi; Julio A Ramirez; James T Summersgill
Journal:  Antimicrob Agents Chemother       Date:  2004-07       Impact factor: 5.191
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