Literature DB >> 3788352

Effects of ciprofloxacin on the humoral and cellular immune responses in Balb/c-mice.

W Roszkowski, H L Ko, K Roszkowski, P Ciborowski, J Jeljaszewicz, G Pulverer.   

Abstract

The effects of a 7 days chemotherapy with ciprofloxacin on the humoral and cellular immune responses in Balb/c-mice were examined. Ciprofloxacin-doses used were calculated on a body weight basis from therapeutic dosages in humans. In a dose-dependent way IgM as well as IgG responses were significantly increased. The delayed-type hypersensitivity reaction to oxazolone was not significantly changed. In in vivo as well in vitro experiments ciprofloxacin showed no modulatory activity on the concanavalin A and LPS-induced proliferative activities of mouse spleen cells.

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Year:  1986        PMID: 3788352     DOI: 10.1016/s0176-6724(86)80013-x

Source DB:  PubMed          Journal:  Zentralbl Bakteriol Mikrobiol Hyg A        ISSN: 0176-6724


  4 in total

Review 1.  Immunological aspects of new quinolones.

Authors:  I Shalit
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1991-04       Impact factor: 3.267

2.  Influence of two quinolones, ofloxacin and pefloxacin, on human myelopoiesis in vitro.

Authors:  F Pallavicini; A Antinori; G Federico; M Fantoni; P Nervo
Journal:  Antimicrob Agents Chemother       Date:  1989-01       Impact factor: 5.191

3.  Effects of cefodizime and cefotaxime on cellular and humoral immune responses.

Authors:  G Pulverer
Journal:  Infection       Date:  1992       Impact factor: 3.553

4.  Modification of immune response in mice by ciprofloxacin.

Authors:  M Jimenez-Valera; A Sampedro; E Moreno; A Ruiz-Bravo
Journal:  Antimicrob Agents Chemother       Date:  1995-01       Impact factor: 5.191

  4 in total

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