Literature DB >> 27098413

A Structures for Lossless Ion Manipulations (SLIM) Module for Collision Induced Dissociation.

Ian K Webb1, Sandilya V B Garimella1, Randolph V Norheim1, Erin S Baker1, Yehia M Ibrahim1, Richard D Smith2.   

Abstract

A collision induced dissociation (CID) structure for lossless ion manipulations (SLIM) module is introduced and coupled to a quadrupole time-of-flight (QTOF) mass spectrometer. The SLIM CID module was mounted after an ion mobility (IM) drift tube to enable IM/CID/MS studies. The efficiency of CID was studied by using the model peptide leucine enkephalin. CID efficiencies (62%) compared favorably with other beam-type CID methods. Additionally, the SLIM CID module was used to fragment a mixture of nine peptides after IM separation. This work also represents the first application of SLIM in the 0.3 to 0.5 Torr pressure regime, an order of magnitude lower in pressure than previously studied. Graphical Abstract ᅟ.

Entities:  

Keywords:  Collision induced dissociation; Conveyor; Ion mobility spectrometry; Ion optics; Manipulation; Peptide fragmentation; rf Confinement

Year:  2016        PMID: 27098413      PMCID: PMC4899216          DOI: 10.1007/s13361-016-1397-x

Source DB:  PubMed          Journal:  J Am Soc Mass Spectrom        ISSN: 1044-0305            Impact factor:   3.109


  34 in total

Review 1.  Proteome analysis by mass spectrometry.

Authors:  P Lee Ferguson; Richard D Smith
Journal:  Annu Rev Biophys Biomol Struct       Date:  2003-01-28

Review 2.  Selected reaction monitoring-based proteomics: workflows, potential, pitfalls and future directions.

Authors:  Paola Picotti; Ruedi Aebersold
Journal:  Nat Methods       Date:  2012-05-30       Impact factor: 28.547

Review 3.  Top-down MS, a powerful complement to the high capabilities of proteolysis proteomics.

Authors:  Fred W McLafferty; Kathrin Breuker; Mi Jin; Xuemei Han; Giuseppe Infusini; Honghai Jiang; Xianglei Kong; Tadhg P Begley
Journal:  FEBS J       Date:  2007-11-16       Impact factor: 5.542

4.  Simultaneous fragmentation of multiple ions using IMS drift time dependent collision energies.

Authors:  Erin Shammel Baker; Keqi Tang; William F Danielson; David C Prior; Richard D Smith
Journal:  J Am Soc Mass Spectrom       Date:  2007-12-04       Impact factor: 3.109

5.  Ion Trapping, Storage, and Ejection in Structures for Lossless Ion Manipulations.

Authors:  Xinyu Zhang; Sandilya V B Garimella; Spencer A Prost; Ian K Webb; Tsung-Chi Chen; Keqi Tang; Aleksey V Tolmachev; Randolph V Norheim; Erin S Baker; Gordon A Anderson; Yehia M Ibrahim; Richard D Smith
Journal:  Anal Chem       Date:  2015-05-26       Impact factor: 6.986

Review 6.  Protein analysis by shotgun/bottom-up proteomics.

Authors:  Yaoyang Zhang; Bryan R Fonslow; Bing Shan; Moon-Chang Baek; John R Yates
Journal:  Chem Rev       Date:  2013-02-26       Impact factor: 60.622

7.  Infrared Spectroscopy of Mobility-Selected H+-Gly-Pro-Gly-Gly (GPGG).

Authors:  Antoine Masson; Michael Z Kamrath; Marta A S Perez; Matthew S Glover; U Rothlisberger; David E Clemmer; Thomas R Rizzo
Journal:  J Am Soc Mass Spectrom       Date:  2015-06-20       Impact factor: 3.109

8.  Implementation of dipolar resonant excitation for collision induced dissociation with ion mobility/time-of-flight MS.

Authors:  Ian K Webb; Tsung-Chi Chen; William F Danielson; Yehia M Ibrahim; Keqi Tang; Gordon A Anderson; Richard D Smith
Journal:  J Am Soc Mass Spectrom       Date:  2014-01-28       Impact factor: 3.109

9.  Experimental evaluation and optimization of structures for lossless ion manipulations for ion mobility spectrometry with time-of-flight mass spectrometry.

Authors:  Ian K Webb; Sandilya V B Garimella; Aleksey V Tolmachev; Tsung-Chi Chen; Xinyu Zhang; Randolph V Norheim; Spencer A Prost; Brian LaMarche; Gordon A Anderson; Yehia M Ibrahim; Richard D Smith
Journal:  Anal Chem       Date:  2014-09-05       Impact factor: 6.986

10.  Mobility-resolved ion selection in uniform drift field ion mobility spectrometry/mass spectrometry: dynamic switching in structures for lossless ion manipulations.

Authors:  Ian K Webb; Sandilya V B Garimella; Aleksey V Tolmachev; Tsung-Chi Chen; Xinyu Zhang; Jonathan T Cox; Randolph V Norheim; Spencer A Prost; Brian LaMarche; Gordon A Anderson; Yehia M Ibrahim; Richard D Smith
Journal:  Anal Chem       Date:  2014-09-26       Impact factor: 6.986

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  6 in total

1.  New frontiers for mass spectrometry based upon structures for lossless ion manipulations.

Authors:  Yehia M Ibrahim; Ahmed M Hamid; Liulin Deng; Sandilya V B Garimella; Ian K Webb; Erin S Baker; Richard D Smith
Journal:  Analyst       Date:  2017-03-27       Impact factor: 4.616

2.  Benchmark Comparison for a Multi-Processing Ion Mobility Calculator in the Free Molecular Regime.

Authors:  Vaibhav Shrivastav; Minal Nahin; Christopher J Hogan; Carlos Larriba-Andaluz
Journal:  J Am Soc Mass Spectrom       Date:  2017-05-05       Impact factor: 3.109

3.  Ion Elevators and Escalators in Multilevel Structures for Lossless Ion Manipulations.

Authors:  Yehia M Ibrahim; Ahmed M Hamid; Jonathan T Cox; Sandilya V B Garimella; Richard D Smith
Journal:  Anal Chem       Date:  2017-01-19       Impact factor: 6.986

4.  A Hybrid Constant and Oscillatory Field Ion Mobility Analyzer Using Structures for Lossless Ion Manipulations.

Authors:  Aneesh Prabhakaran; Ahmed M Hamid; Sandilya V B Garimella; Blandina R Valenzuela; Robert G Ewing; Yehia M Ibrahim; Richard D Smith
Journal:  J Am Soc Mass Spectrom       Date:  2017-12-12       Impact factor: 3.109

5.  Compression Ratio Ion Mobility Programming (CRIMP) Accumulation and Compression of Billions of Ions for Ion Mobility-Mass Spectrometry Using Traveling Waves in Structures for Lossless Ion Manipulations (SLIM).

Authors:  Liulin Deng; Sandilya V B Garimella; Ahmed M Hamid; Ian K Webb; Isaac K Attah; Randolph V Norheim; Spencer A Prost; Xueyun Zheng; Jeremy A Sandoval; Erin S Baker; Yehia M Ibrahim; Richard D Smith
Journal:  Anal Chem       Date:  2017-05-25       Impact factor: 6.986

6.  Identification of Mobility-Resolved N-Glycan Isomers.

Authors:  Ahmed Ben Faleh; Stephan Warnke; Priyanka Bansal; Robert P Pellegrinelli; Irina Dyukova; Thomas R Rizzo
Journal:  Anal Chem       Date:  2022-07-07       Impact factor: 8.008

  6 in total

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