Literature DB >> 25971536

Ion Trapping, Storage, and Ejection in Structures for Lossless Ion Manipulations.

Xinyu Zhang1, Sandilya V B Garimella1, Spencer A Prost1, Ian K Webb1, Tsung-Chi Chen1, Keqi Tang1, Aleksey V Tolmachev1, Randolph V Norheim1, Erin S Baker1, Gordon A Anderson1, Yehia M Ibrahim1, Richard D Smith1.   

Abstract

A new Structures for Lossless Ion Manipulations (SLIM) module, having electrode arrays patterned on a pair of parallel printed circuit boards (PCB), was constructed and utilized to investigate capabilities for ion trapping at a pressure of 4 Torr. Positive ions were confined by application of RF voltages to a series of inner rung electrodes with alternating phase on adjacent electrodes, in conjunction with positive DC potentials on surrounding guard electrodes on each PCB. An axial DC field was also introduced by stepwise varying the DC potentials applied to the inner rung electrodes to control the ion transport and accumulation inside the ion trapping region. We show that ions can be trapped and accumulated with up to 100% efficiency, stored for at least 5 h with no significant losses, and then could be rapidly ejected from the SLIM trap. The present results provide a foundation for the development of much more complex SLIM devices that facilitate extended ion manipulations.

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Year:  2015        PMID: 25971536      PMCID: PMC4523076          DOI: 10.1021/acs.analchem.5b00214

Source DB:  PubMed          Journal:  Anal Chem        ISSN: 0003-2700            Impact factor:   6.986


  23 in total

1.  Radial stratification of ions as a function of mass to charge ratio in collisional cooling radio frequency multipoles used as ion guides or ion traps.

Authors:  A V Tolmachev; H R Udseth; R D Smith
Journal:  Rapid Commun Mass Spectrom       Date:  2000       Impact factor: 2.419

2.  Development of high-sensitivity ion trap ion mobility spectrometry time-of-flight techniques: a high-throughput nano-LC-IMS-TOF separation of peptides arising from a Drosophila protein extract.

Authors:  Sunnie Myung; Young Jin Lee; Myeong Hee Moon; John Taraszka; Rena Sowell; Stormy Koeniger; Amy E Hilderbrand; Stephen J Valentine; Lucy Cherbas; Peter Cherbas; Thomas C Kaufmann; David F Miller; Yehia Mechref; Milos V Novotny; Michael A Ewing; C Ray Sporleder; David E Clemmer
Journal:  Anal Chem       Date:  2003-10-01       Impact factor: 6.986

3.  Size-dependent electron-impact detachment of internally cold Cn- and Aln- clusters.

Authors:  A Diner; Y Toker; D Strasser; O Heber; I Ben-Itzhak; P D Witte; A Wolf; D Schwalm; M L Rappaport; K G Bhushan; D Zajfman
Journal:  Phys Rev Lett       Date:  2004-08-04       Impact factor: 9.161

4.  Ion mobility spectrometry-mass spectrometry performance using electrodynamic ion funnels and elevated drift gas pressures.

Authors:  Erin Shammel Baker; Brian H Clowers; Fumin Li; Keqi Tang; Aleksey V Tolmachev; David C Prior; Mikhail E Belov; Richard D Smith
Journal:  J Am Soc Mass Spectrom       Date:  2007-04-06       Impact factor: 3.109

5.  Enhanced ion utilization efficiency using an electrodynamic ion funnel trap as an injection mechanism for ion mobility spectrometry.

Authors:  Brian H Clowers; Yehia M Ibrahim; David C Prior; William F Danielson; Mikhail E Belov; Richard D Smith
Journal:  Anal Chem       Date:  2008-01-01       Impact factor: 6.986

6.  Collisional focusing effects in radio frequency quadrupoles.

Authors:  D J Douglas; J B French
Journal:  J Am Soc Mass Spectrom       Date:  1992-05       Impact factor: 3.109

7.  Ion trap mass analysis at high pressure: an experimental characterization.

Authors:  Qingyu Song; Wei Xu; Scott A Smith; Liang Gao; William J Chappell; R Graham Cooks; Zheng Ouyang
Journal:  J Mass Spectrom       Date:  2010-01       Impact factor: 1.982

8.  Experimental evaluation and optimization of structures for lossless ion manipulations for ion mobility spectrometry with time-of-flight mass spectrometry.

Authors:  Ian K Webb; Sandilya V B Garimella; Aleksey V Tolmachev; Tsung-Chi Chen; Xinyu Zhang; Randolph V Norheim; Spencer A Prost; Brian LaMarche; Gordon A Anderson; Yehia M Ibrahim; Richard D Smith
Journal:  Anal Chem       Date:  2014-09-05       Impact factor: 6.986

9.  Characterization of ion dynamics in structures for lossless ion manipulations.

Authors:  Aleksey V Tolmachev; Ian K Webb; Yehia M Ibrahim; Sandilya V B Garimella; Xinyu Zhang; Gordon A Anderson; Richard D Smith
Journal:  Anal Chem       Date:  2014-09-04       Impact factor: 6.986

10.  Mobility-resolved ion selection in uniform drift field ion mobility spectrometry/mass spectrometry: dynamic switching in structures for lossless ion manipulations.

Authors:  Ian K Webb; Sandilya V B Garimella; Aleksey V Tolmachev; Tsung-Chi Chen; Xinyu Zhang; Jonathan T Cox; Randolph V Norheim; Spencer A Prost; Brian LaMarche; Gordon A Anderson; Yehia M Ibrahim; Richard D Smith
Journal:  Anal Chem       Date:  2014-09-26       Impact factor: 6.986

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  28 in total

1.  Structural Elucidation of cis/trans Dicaffeoylquinic Acid Photoisomerization Using Ion Mobility Spectrometry-Mass Spectrometry.

Authors:  Xueyun Zheng; Ryan S Renslow; Mpho M Makola; Ian K Webb; Liulin Deng; Dennis G Thomas; Niranjan Govind; Yehia M Ibrahim; Mwadham M Kabanda; Ian A Dubery; Heino M Heyman; Richard D Smith; Ntakadzeni E Madala; Erin S Baker
Journal:  J Phys Chem Lett       Date:  2017-03-15       Impact factor: 6.475

Review 2.  Miniature and Fieldable Mass Spectrometers: Recent Advances.

Authors:  Dalton T Snyder; Christopher J Pulliam; Zheng Ouyang; R Graham Cooks
Journal:  Anal Chem       Date:  2015-10-21       Impact factor: 6.986

3.  New frontiers for mass spectrometry based upon structures for lossless ion manipulations.

Authors:  Yehia M Ibrahim; Ahmed M Hamid; Liulin Deng; Sandilya V B Garimella; Ian K Webb; Erin S Baker; Richard D Smith
Journal:  Analyst       Date:  2017-03-27       Impact factor: 4.616

Review 4.  Common cases of improper lipid annotation using high-resolution tandem mass spectrometry data and corresponding limitations in biological interpretation.

Authors:  Jeremy P Koelmel; Candice Z Ulmer; Christina M Jones; Richard A Yost; John A Bowden
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2017-03-02       Impact factor: 4.698

5.  Spatial Ion Peak Compression and its Utility in Ion Mobility Spectrometry.

Authors:  Sandilya V B Garimella; Yehia M Ibrahim; Keqi Tang; Ian K Webb; Erin S Baker; Aleksey V Tolmachev; Tsung-Chi Chen; Gordon A Anderson; Richard D Smith
Journal:  J Am Soc Mass Spectrom       Date:  2016-04-06       Impact factor: 3.109

6.  Ion Elevators and Escalators in Multilevel Structures for Lossless Ion Manipulations.

Authors:  Yehia M Ibrahim; Ahmed M Hamid; Jonathan T Cox; Sandilya V B Garimella; Richard D Smith
Journal:  Anal Chem       Date:  2017-01-19       Impact factor: 6.986

7.  Dual Polarity Ion Confinement and Mobility Separations.

Authors:  Isaac K Attah; Sandilya V B Garimella; Ian K Webb; Gabe Nagy; Randolph V Norheim; Colby E Schimelfenig; Yehia M Ibrahim; Richard D Smith
Journal:  J Am Soc Mass Spectrom       Date:  2019-03-04       Impact factor: 3.109

8.  Mobility-Selected Ion Trapping and Enrichment Using Structures for Lossless Ion Manipulations.

Authors:  Tsung-Chi Chen; Yehia M Ibrahim; Ian K Webb; Sandilya V B Garimella; Xing Zhang; Ahmed M Hamid; Liulin Deng; William E Karnesky; Spencer A Prost; Jeremy A Sandoval; Randolph V Norheim; Gordon A Anderson; Aleksey V Tolmachev; Erin S Baker; Richard D Smith
Journal:  Anal Chem       Date:  2016-01-21       Impact factor: 6.986

9.  Characterization of Traveling Wave Ion Mobility Separations in Structures for Lossless Ion Manipulations.

Authors:  Ahmed M Hamid; Yehia M Ibrahim; Sandilya V B Garimella; Ian K Webb; Liulin Deng; Tsung-Chi Chen; Gordon A Anderson; Spencer A Prost; Randolph V Norheim; Aleksey V Tolmachev; Richard D Smith
Journal:  Anal Chem       Date:  2015-10-28       Impact factor: 6.986

10.  Design of a TW-SLIM Module for Dual Polarity Confinement, Transport, and Reactions.

Authors:  Sandilya V B Garimella; Ian K Webb; Aneesh Prabhakaran; Isaac K Attah; Yehia M Ibrahim; Richard D Smith
Journal:  J Am Soc Mass Spectrom       Date:  2017-05-30       Impact factor: 3.109

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