Literature DB >> 27037609

Doubly robust survival trees.

Jon Arni Steingrimsson1, Liqun Diao2, Annette M Molinaro3, Robert L Strawderman4.   

Abstract

Estimating a patient's mortality risk is important in making treatment decisions. Survival trees are a useful tool and employ recursive partitioning to separate patients into different risk groups. Existing 'loss based' recursive partitioning procedures that would be used in the absence of censoring have previously been extended to the setting of right censored outcomes using inverse probability censoring weighted estimators of loss functions. In this paper, we propose new 'doubly robust' extensions of these loss estimators motivated by semiparametric efficiency theory for missing data that better utilize available data. Simulations and a data analysis demonstrate strong performance of the doubly robust survival trees compared with previously used methods.
Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Entities:  

Keywords:  CART; censored data; inverse probability of censoring weighted estimation; loss estimation; regression trees; semiparametric estimation

Mesh:

Year:  2016        PMID: 27037609      PMCID: PMC7286558          DOI: 10.1002/sim.6949

Source DB:  PubMed          Journal:  Stat Med        ISSN: 0277-6715            Impact factor:   2.373


  6 in total

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