| Literature DB >> 27037609 |
Jon Arni Steingrimsson1, Liqun Diao2, Annette M Molinaro3, Robert L Strawderman4.
Abstract
Estimating a patient's mortality risk is important in making treatment decisions. Survival trees are a useful tool and employ recursive partitioning to separate patients into different risk groups. Existing 'loss based' recursive partitioning procedures that would be used in the absence of censoring have previously been extended to the setting of right censored outcomes using inverse probability censoring weighted estimators of loss functions. In this paper, we propose new 'doubly robust' extensions of these loss estimators motivated by semiparametric efficiency theory for missing data that better utilize available data. Simulations and a data analysis demonstrate strong performance of the doubly robust survival trees compared with previously used methods.Entities:
Keywords: CART; censored data; inverse probability of censoring weighted estimation; loss estimation; regression trees; semiparametric estimation
Mesh:
Year: 2016 PMID: 27037609 PMCID: PMC7286558 DOI: 10.1002/sim.6949
Source DB: PubMed Journal: Stat Med ISSN: 0277-6715 Impact factor: 2.373