Literature DB >> 35755402

ANALYSIS OF REGRESSION DISCONTINUITY DESIGNS USING CENSORED DATA.

Youngjoo Cho1, Chen Hu2, Debashis Ghosh3.   

Abstract

In many medical and scientific settings, the choice of treatment or intervention may be determined by a covariate threshold. For example, elderly men may receive more thorough diagnosis if their prostate-specific antigen (PSA) level is high. In these cases, the causal treatment effect is often of great interest, especially when there is a lack of evidence from randomized clinical trials. From the social science literature, a class of methods known as regression discontinuity (RD) designs can be used to estimate the treatment effect in this situation. Under certain assumptions, such an estimand enjoys a causal interpretation. We show how to estimate causal effects under the regression discontinuity design for censored data. The proposed estimation procedure employs a class of censoring unbiased transformations that includes inverse probability censored weighting and doubly robust transformation schemes. Simulation studies are used to evaluate the finite-sample properties of the proposed estimator. We also illustrate the proposed method by evaluating the causal effect of PSA-dependent screening strategies.

Entities:  

Keywords:  Causal effect; Double robustness; Instrumental variable; Observational studies; Survival analysis

Year:  2021        PMID: 35755402      PMCID: PMC9221554     

Source DB:  PubMed          Journal:  J Stat Res        ISSN: 0256-422X


  9 in total

1.  Efficacy of Prostate-Specific Antigen Screening: Use of Regression Discontinuity in the PLCO Cancer Screening Trial.

Authors:  Jonathan Shoag; Joshua Halpern; Brian Eisner; Richard Lee; Sameer Mittal; Christopher E Barbieri; Daniel Shoag
Journal:  JAMA Oncol       Date:  2015-10       Impact factor: 31.777

2.  A doubly robust censoring unbiased transformation.

Authors:  Daniel Rubin; Mark J van der Laan
Journal:  Int J Biostat       Date:  2007       Impact factor: 0.968

Review 3.  Regression discontinuity designs are underutilized in medicine, epidemiology, and public health: a review of current and best practice.

Authors:  Ellen Moscoe; Jacob Bor; Till Bärnighausen
Journal:  J Clin Epidemiol       Date:  2015-02       Impact factor: 6.437

4.  Doubly-robust estimators of treatment-specific survival distributions in observational studies with stratified sampling.

Authors:  Xiaofei Bai; Anastasios A Tsiatis; Sean M O'Brien
Journal:  Biometrics       Date:  2013-10-11       Impact factor: 2.571

5.  Censoring Unbiased Regression Trees and Ensembles.

Authors:  Jon Arni Steingrimsson; Liqun Diao; Robert L Strawderman
Journal:  J Am Stat Assoc       Date:  2018-07-09       Impact factor: 5.033

6.  Mortality results from a randomized prostate-cancer screening trial.

Authors:  Gerald L Andriole; E David Crawford; Robert L Grubb; Saundra S Buys; David Chia; Timothy R Church; Mona N Fouad; Edward P Gelmann; Paul A Kvale; Douglas J Reding; Joel L Weissfeld; Lance A Yokochi; Barbara O'Brien; Jonathan D Clapp; Joshua M Rathmell; Thomas L Riley; Richard B Hayes; Barnett S Kramer; Grant Izmirlian; Anthony B Miller; Paul F Pinsky; Philip C Prorok; John K Gohagan; Christine D Berg
Journal:  N Engl J Med       Date:  2009-03-18       Impact factor: 91.245

7.  Doubly robust survival trees.

Authors:  Jon Arni Steingrimsson; Liqun Diao; Annette M Molinaro; Robert L Strawderman
Journal:  Stat Med       Date:  2016-03-31       Impact factor: 2.373

8.  Regression discontinuity designs in epidemiology: causal inference without randomized trials.

Authors:  Jacob Bor; Ellen Moscoe; Portia Mutevedzi; Marie-Louise Newell; Till Bärnighausen
Journal:  Epidemiology       Date:  2014-09       Impact factor: 4.822

9.  Double propensity-score adjustment: A solution to design bias or bias due to incomplete matching.

Authors:  Peter C Austin
Journal:  Stat Methods Med Res       Date:  2016-09-30       Impact factor: 3.021

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.