Literature DB >> 2703234

Fragile sites and statistics.

T Mariani1.   

Abstract

A simple and reliable statistical method is proposed to distinguish real fragile sites from the casual accumulation of aberrations that can occur as a consequence of random distribution. It is based on a study of the expected random distribution, assumed to be equal to a Poisson distribution, with the expected value of events per band as the mean.

Mesh：

Year:  1989        PMID： 2703234     DOI： 10.1007/BF00283683

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  9 in total

1.  Fragile sites induced by FUdR, caffeine, and aphidicolin. Their frequency, distribution, and analysis.

Authors:  P N Rao; N A Heerema; C G Palmer
Journal:  Hum Genet       Date:  1988-01       Impact factor: 4.132

2.  Fragile sites are targets of diverse mutagens and carcinogens.

Authors:  J J Yunis; A L Soreng; A E Bowe
Journal:  Oncogene       Date:  1987-03       Impact factor: 9.867

3.  Site-specific chromosomal rearrangements induced in human diploid cells by x-irradiation.

Authors:  Y Kano; J B Little
Journal:  Cytogenet Cell Genet       Date:  1986

4.  Comparison of expression of the fragile site at Xq27 in T and B lymphocytes.

Authors:  C A Marchese; M S Lin; M G Wilson
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

5.  Nonrandom distribution of methotrexate-induced aberrations on human chromosomes. Detection of further folic acid sensitive fragile sites.

Authors:  G Barbi; P Steinbach; W Vogel
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

6.  Variation in the expression of aphidicolin-induced fragile sites in human lymphocyte cultures.

Authors:  A P Craig-Holmes; L C Strong; A Goodacre; S Pathak
Journal:  Hum Genet       Date:  1987-06       Impact factor: 4.132

7.  The effect of 1-beta-D-arabinofuranosyl-cytosine on the expression of the common fragile site at 3p14.

Authors:  X Z Li; Z A Yan; X T Zhou
Journal:  Hum Genet       Date:  1986-12       Impact factor: 4.132

8.  DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes.

Authors:  T W Glover; C Berger; J Coyle; B Echo
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

9.  Human chromosome hot points. V. The effect of four nucleosides on chromosomes in folate-free medium.

Authors:  N Li; Y Wu; X T Zhou
Journal:  Hum Genet       Date:  1986-09       Impact factor: 4.132
  9 in total
  5 in total

1.  Fragile sites and statistics.

Authors:  M De Braekeleer
Journal:  Hum Genet       Date:  1989-12       Impact factor: 4.132

2.  Variability in expression of common fragile sites: in search of a new criterion.

Authors:  D K Jordan; T L Burns; J E Divelbiss; R F Woolson; S R Patil
Journal:  Hum Genet       Date:  1990-10       Impact factor: 4.132

3.  Identifying chromosomal fragile sites from individuals: a multinomial statistical model.

Authors:  U Böhm; P F Dahm; B F McAllister; I F Greenbaum
Journal:  Hum Genet       Date:  1995-03       Impact factor: 4.132

Review 4.  Fragile sites in cancer: more than meets the eye.

Authors:  Thomas W Glover; Thomas E Wilson; Martin F Arlt
Journal:  Nat Rev Cancer       Date:  2017-07-25       Impact factor: 60.716

5.  Association between Genomic Instability and Evolutionary Chromosomal Rearrangements in Neotropical Primates.

Authors:  Fiona Puntieri; Nancy B Andrioli; Mariela Nieves
Journal:  Genome Biol Evol       Date:  2018-07-01       Impact factor: 3.416
  5 in total

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