Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Comparison of expression of the fragile site at Xq27 in T and B lymphocytes.

Literature DB >> 6611290

Comparison of expression of the fragile site at Xq27 in T and B lymphocytes.

Abstract

We compared the fragile X (fraX) expression in T and B lymphocytes from four hemizygous males with fraX. Blood cultures were stimulated with a T cell mitogen (phytohemagglutinin:PHA) and with a B cell mitogen (pokeweed mitogen:PWM). A significant decrease in fraX expression was observed in cultures stimulated with PWM when compared to PHA-stimulated ones.

Entities: Disease Species

Mesh：

Substances：

Year: 1984 PMID： 6611290 DOI： 10.1007/bf00273003

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

6 in total

1. Replication of human chromosomes in human-mouse hybrids: evidence that the timing of DNA synthesis is determined independently in each human chromosome.

Authors: M S Lin; R L Davidson
Journal: Somatic Cell Genet Date: 1975-01

2. Heritable fragile sites on human chromosomes I. Factors affecting expression in lymphocyte culture.

Authors: G R Sutherland
Journal: Am J Hum Genet Date: 1979-03 Impact factor: 11.025

3. The fragile X(q27) form of X-linked mental retardation: FUdR as an inducing agent for fra(X)(q27) expression in lymphocytes, fibroblasts, and amniocytes.

Authors: R Brookwell; A Daniel; G Turner; J Fishburn
Journal: Am J Med Genet Date: 1982-10

4. Expression of the marker (X) (q28) in lymphoblastoid cell lines.

Authors: P A Jacobs; P A Hunt; M Mayer; J C Wang; G R Boss; R W Erbe
Journal: Am J Hum Genet Date: 1982-07 Impact factor: 11.025

5. Kinetics of mitogen-induced proliferation and differentiation of human peripheral blood B lymphocytes.

Authors: T V Shankey; R P Daniele; P C Nowell
Journal: Clin Exp Immunol Date: 1981-04 Impact factor: 4.330

6. The fragile X: a scanning electron microscope study.

Authors: C J Harrison; E M Jack; T D Allen; R Harris
Journal: J Med Genet Date: 1983-08 Impact factor: 6.318

6 in total

4 in total

Comparison of expression of the fragile site at Xq27 in T and B lymphocytes.

1. Replication of human chromosomes in human-mouse hybrids: evidence that the timing of DNA synthesis is determined independently in each human chromosome.

2. Heritable fragile sites on human chromosomes I. Factors affecting expression in lymphocyte culture.

3. The fragile X(q27) form of X-linked mental retardation: FUdR as an inducing agent for fra(X)(q27) expression in lymphocytes, fibroblasts, and amniocytes.

4. Expression of the marker (X) (q28) in lymphoblastoid cell lines.

5. Kinetics of mitogen-induced proliferation and differentiation of human peripheral blood B lymphocytes.

6. The fragile X: a scanning electron microscope study.

1. Fragile sites and statistics.

2. Studies on three rare fragile sites. 2q13, 12q13, and 17p12 segregating in one family.

3. Fragile X syndrome: clinical, cytogenetic, biochemical and molecular features.

4. Replication status of fragile X(q27.3) in 13 female heterozygotes.